Is medication profitable to sell on Amazon United States?

The niche generates $135K/yr across 19 tracked products. 90-day search growth is -7.9%. Flapen's verdict: Skip it (32/100).

How competitive is the medication niche?

7 brands and 103 sellers compete. The top 5 products take 69% of clicks and top 5 brands hold 96% of demand.

What do buyers complain about in medication?

Top complaints mined from reviews: Adhesion/Stickiness, Allergies, Skin Health. The return rate is 0.5%.

When does demand for medication peak?

Demand peaks in Jan; the busiest month runs 2.7× the quietest.

What does it cost to enter the medication niche?

Listings span $3.61–$24.37; the average listing price is $13.08 (sweet spot $15–$100). The average incumbent carries 36,041 reviews — the moat a new listing must climb.

medication

Skip it

A deep review moat (36,041 avg reviews) — this niche doesn't clear our bar today.

Returns

Incredible0.5%

return rate — above 5% kills the launch gate

Avg price

Good$13.08

avg listing price — sweet spot $15–$100

Price range

Okay$3.61–$24.37

cheapest to priciest tracked listing — scored on the share inside $15–$100

Market size

Okay$135K

$135K/yr · 532K searches

Competition

Okay69%

top-5 click share — leaders hold, buyers still browse

Conversion

Bad1.9%

search→purchase rate — share of searches ending in a sale

Growth

Bad-7.9%

90-day search growth — must beat 0% to launch

Quality gap

Bad4.7★

avg incumbent rating — lower means beatable quality

Brand share

Bad96%

top-5 brand share — brand-locked demand

Review moat

Bad36,040.95

avg incumbent reviews — the moat a new listing must climb

According to Flapen's Amazon United States niche tracking, medication is a $135K/yr Amazon United States market (532K searches/yr). The top 5 brands hold 96% of demand. Demand peaks in Jan. Verdict: Skip it — 32/100.

Data updated Jul 16, 2026 · scored weekly · How we score niches

medication market data

Units sold / yr: 15K–20K; avg 750–1,000/product
Revenue / yr: $196K–$262K; units × avg price
Conversion rate: 1.9%
Avg BSR: #16
Page quality: 0%
Prime: 100%
Sponsored: 89%
Out of stock: 0.0%
Avg brand age: 92 months
Avg seller age: 140 days

Competition & brand share

The top 5 products take 69% of clicks — established leaders, but buyers still shop beyond them.

Brands

7 falling

Sellers

103

Top-5 brand share

96%

Top 20: 100%

Top-5 click share

69%

Top 20: 100%

Open market

medicube61%
Amazon Basic Care20%
Tylenol9%
TUMS4%
Pepto Bismol3%
ProsourceFit2%
Open — no brand owns it (1 brand, 2%)

Demand & seasonality

Weekly Amazon search volume, last 104 weeks — -7.9% search growth over the last 90 days.

Peak months: Jan · busiest ÷ quietest = 2.7×

Open Trend

Top medication search terms

medicibe248K/yr +3.2%0.7% conv.
medication166K/yr -19.6%1.4% conv.
meds28K/yr +1.3%0.5% conv.
medications24K/yr -9.3%0.7% conv.
fsa eligible medication only list16K/yr -41.9%1.3% conv.
medicinas9K/yr -4.3%0.1% conv.
otc meds6K/yr +29.6%1.7% conv.
medicamento7K/yr -6.3%0.3% conv.
otc medications5K/yr +15.6%1.1% conv.
hsa store eligible medication3K/yr +27.2%1.2% conv.

All search terms

Top medication products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 19 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

medicube Toner Pads Zero Pore Pad 2.0 | Dual-Textured Facial Pad for Exfoliation and Pore Care with 4.5% AHA Lactic Acid 0.45% BHA Salicylic Acid | Ideal for All Korean Skin Care 70 Pads (1 Pack)

medicube$16.534.6★27,398 rev

medicube PDRN Pink Peptide Serum with Salmon DNA | Pink Glow Serum with Peptides & Niacinamide for Hydration & Firm-Looking Skin | Uneven Tone Care | Korean Skincare 1.01 fl. Oz

medicube$16.934.7★17,956 rev

Basic Care Ibuprofen Tablets 500 Count

Amazon Basic Care$8.834.8★96,192 rev

medicube Jelly Cream with Collagen Niacinamide | Freeze-Dried Hydrolyzed Collagen for Skin Barrier Hydration & 24H Glow | Plumper Firmer looking skin | 3.71 fl.oz

medicube$16.194.4★29,990 rev

Tylenol Rapid Release Extra Strength Gelcaps Acetaminophen 500 mg per Gel Laser Drilled Holes Allow Fast Strong Pain Relief Fever Reducer Gentle on Stomach 100 Count Size

Tylenol$12.024.8★89,013 rev

Newest

by launch date

medicube PDRN Pink Peptide Serum with Salmon DNA | Pink Glow Serum with Peptides & Niacinamide for Hydration & Firm-Looking Skin | Uneven Tone Care | Korean Skincare 1.01 fl. Oz

medicube$16.9317,956 rev

1y ago

medicube Capsule Cream with Deep Vitamin C | Liposome Vitamin C Golden Capsule for Radiance & Firm-Looking Skin | Hydrating Glow Gel Texture | Korean Skincare 1.94 oz

medicube$17.9213,956 rev

2y ago

medicube Jelly Cream with Collagen Niacinamide | Freeze-Dried Hydrolyzed Collagen for Skin Barrier Hydration & 24H Glow | Plumper Firmer looking skin | 3.71 fl.oz

medicube$16.1929,990 rev

2y ago

medicube Wrapping Mask Collagen Overnight Peel Off Facial Mask | Elasticity & Hydration Care Reduces Sagging & Dullness | Hydrolyzed Collagen For Glowing Skin | Korean Skin Care 2.53 fl.oz

medicube$16.3622,152 rev

3y ago

medicube Triple Collagen Cream - Hydrating & Firming Moisturizer with Hyaluronic Acid Premium Elastin Shea Butter - Wrinkle Care & Boosts Elasticity - Korean Skincare 1.69 oz

medicube$18.378,940 rev

3y ago

What buyers say about medication

What buyers praise and complain about, mined from review topics.

What buyers love

Suitability Combination Skin12%

“Good for sensitive skin”

Moist/Dry11%

“Super hydrating”

Quality-Overall10%

“Great quality the prices is affordable —I recommend this product”

Value For Money10%

“Very Economical”

Soft Feel9%

“Makes my skin so soft”

Brightness/Shine/Glow4%

“Gives a glow”

Suitability Dry Skin4%

“Effective exfoliation and smoother skin”

Efficiency4%

“Works perfectly”

Advertised Vs Actual Product3%

“AS ADVERTISED”

Ease Of Use3%

“Easier to open”

What buyers complain about

Adhesion/Stickiness10%

“then its not sticky anymore”

Allergies10%

“ALLERGIC REACTION”

Skin Health6%

“Burns my face”

Functionality-Overall6%

“No results”

Moist/Dry6%

“NOT moisturizing”

Smell4%

“Dont like the scent”

Suitability Dry Skin3%

“it may not be rich enough for very dry skin”

Value For Money3%

“Not worth the price”

Sensitivity-Overall3%

“Would not recommend if you have sensitive skin”

Ease Of Use2%

“Hard to open”

Top return reasons

Functionality-Overall14%

Adhesion/Stickiness10%

Advertised Vs Actual Product9%

Value For Money8%

Moist/Dry7%

Smell7%