Is tooth pain relief for adults profitable to sell on Amazon United States?

The niche generates $2.7M/yr across 18 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is +0.3%. Flapen's verdict: Worth a look (54/100).

How competitive is the tooth pain relief for adults niche?

9 brands and 108 sellers compete. The top 5 products take 64% of clicks and top 5 brands hold 93% of demand.

What do buyers complain about in tooth pain relief for adults?

Top complaints mined from reviews: Functionality-Overall, Oral Hygiene, Pain Relief-Overall. The return rate is 0.2%.

When does demand for tooth pain relief for adults peak?

Demand is steady year-round — the busiest month runs 1.3× the quietest.

What does it cost to enter the tooth pain relief for adults niche?

Listings span $6.06–$21.35; the average listing price is $10.11 (sweet spot $15–$100). The average incumbent carries 6,957 reviews — the moat a new listing must climb.

tooth pain relief for adults

Worth a look

Shows low returns (0.2%), but brand-locked demand (top 5 brands take 93% of clicks) keeps it on the watch list.

Returns

Incredible0.2%

return rate — above 5% kills the launch gate

Conversion

Incredible16.6%

search→purchase rate — share of searches ending in a sale

Market size

Incredible$2.7M

$2.7M/yr · 1.6M searches

Price range

Okay$6.06–$21.35

cheapest to priciest tracked listing — scored on the share inside $15–$100

Quality gap

Okay4.5★

avg incumbent rating — lower means beatable quality

Competition

Okay64%

top-5 click share — leaders hold, buyers still browse

Avg price

Okay$10.11

avg listing price — sweet spot $15–$100

Growth

Okay+0.3%

90-day search growth — must beat 0% to launch

Review moat

Bad6,957.22

avg incumbent reviews — the moat a new listing must climb

Brand share

Bad93%

top-5 brand share — brand-locked demand

According to Flapen's Amazon United States niche tracking, tooth pain relief for adults is a $2.7M/yr Amazon United States market (1.6M searches/yr). The top 5 brands hold 93% of demand. Verdict: Worth a look — 54/100.

Data updated Jul 14, 2026 · scored weekly · How we score niches

tooth pain relief for adults market data

Units sold / yr: 250K–300K; avg 15,000–20,000/product
Revenue / yr: $2.5M–$3.0M; units × avg price
Conversion rate: 16.6%
Avg BSR: #23
Page quality: 0%
Prime: 100%
Sponsored: 78%
Out of stock: 0.0%
Avg brand age: 71 months
Avg seller age: 145 days

Competition & brand share

The top 5 products take 64% of clicks — established leaders, but buyers still shop beyond them.

Brands

9 rising

Sellers

108

Top-5 brand share

93%

Top 20: 100%

Top-5 click share

64%

Top 20: 100%

Open market

Orajel66%
DenTek11%
Anbesol11%
Generic3%
MENTHOLATUM COMPANY INC ***2%
Boiron2%
Open — no brand owns it (3 brands, 5%)

Demand & seasonality

Weekly Amazon search volume, last 104 weeks — +0.3% search growth over the last 90 days.

No pronounced peak months · busiest ÷ quietest = 1.3×

Open Trend

Top tooth pain relief for adults search terms

orajel347K/yr +3.7%19.3% conv.
orajel toothache pain relief gel169K/yr -2.2%24.4% conv.
tooth pain relief for adults158K/yr +0.1%12.0% conv.
toothache pain relief adult severe134K/yr -4.2%14.0% conv.
oragel88K/yr +5.1%21.2% conv.
tooth pain93K/yr -8.5%10.3% conv.
toothache pain relief86K/yr +9.9%8.3% conv.
oragel maximum strength nighttime toothache pain relief cream67K/yr +8.1%25.7% conv.
tooth ache nerve pain medicine62K/yr -17.6%14.2% conv.
toothache54K/yr +8.2%8.4% conv.

All search terms

Top tooth pain relief for adults products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 18 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Orajel 4X for Toothache & Gum Pain: Severe Cream Tube 0.33oz- From Oral Pain Relief Brand

Orajel$7.784.7★12,342 rev

DenTek Instant Oral Pain Relief with Benzocaine for Toothache Pain Relief 50 Disposable Applicators

DenTek$6.814.4★19,477 rev

Orajel 3X for Mouth Sores: Maximum Strength Gel Tube 0.42oz- from #1 Oral Pain Relief Brand

Orajel$6.664.6★6,967 rev

Orajel 3X Medicated Toothache & Gum Pain Gel Immediate Pain Relief Extra Strength 0.42 oz

Orajel$6.794.7★6,555 rev

Anbesol Maximum Strength Gel - Instant Oral Pain Relief for Toothaches Gums Braces & Denture Pain and Mouth Sores* Canker Sore Treatment Inside Mouth ADA Accepted 0.33 oz

Anbesol$6.794.6★18,044 rev

Newest

by launch date

Tooth Pain Relief for Adults Spray Treatment Toothache Nerve Pain Medicine Quicklynumbs Nerve Wisdom Tooth Inflammation Red and Swollen Gums and Other Types of Dental1Pcs

Generic$18.68243 rev

11mo ago

Orajel Rescue Relief Pen with Menthol Cooling Gel for Instant Pain Relief of Tooth & Gum Mouth Sores Braces and Denture Irritation Touch-Free Silicone Applicator 0.07 oz (2-Pack)

Orajel$16.28598 rev

1y ago

HIQILI Clove Essential Oil for Teeth and Gums Oral Care Diffuser Skin

HIQILI$6.953,690 rev

3y ago

Anbesol Maximum Strength Liquid - Instant Oral Pain Relief for Toothaches Gums Braces & Denture Pain and Mouth Sores* Canker Sore Treatment Inside Mouth ADA Accepted 0.41 oz

Anbesol$6.833,562 rev

3y ago

Dentemp Maximum Strength Loose Cap and Lost Filling Repair - Dental Repair Kit for Instant Pain Relief - Value Pack (Packaging May Vary)

Dentemp$10.335,315 rev

4y ago

What buyers say about tooth pain relief for adults

What buyers praise and complain about, mined from review topics.

What buyers love

Tooth Sensitivity19%

“It really helped to calm my severe toothache”

Efficiency13%

“Works well”

Oral Hygiene12%

“Great for your gums”

Quality-Overall9%

“EXCELLENT product”

Advertised Vs Actual Product5%

“As advertised”

Value For Money5%

“great value”

Ease Of Use4%

“It was easy to put on”

Ease Of Application3%

“Easy to apply”

Taste-Overall2%

“Strong taste”

Strength2%

“Strong and effective”

What buyers complain about

Functionality-Overall12%

“Not very effective”

Oral Hygiene12%

“cant get to a dentist”

Pain Relief-Overall10%

“Hurts”

Taste-Overall7%

“It tastes really weird”

Value For Money5%

“Waste of money”

Tooth Sensitivity4%

“doesn't help tooth-aches at all”

Durability4%

“Has to break in to it”

Ease Of Use3%

“Very hard to open the tube”

Smell2%

“It smelled like a chemical”

Side Effects2%

“Bad for body”

Top return reasons

Advertised Vs Actual Product25%

Smell11%

Functionality-Overall9%

Leak-Proof8%

Size-Overall5%

Oral Hygiene5%