Is serrapeptase profitable to sell on Amazon United States?

The niche generates $652K/yr across 17 tracked products. 90-day search growth is -6.8%. Flapen's verdict: Worth a look (56/100).

How competitive is the serrapeptase niche?

15 brands and 30 sellers compete. The top 5 products take 67% of clicks and top 5 brands hold 74% of demand.

What do buyers complain about in serrapeptase?

Top complaints mined from reviews: Ingredients-Overall, Dosage, Regulates Digestion. The return rate is 0.0%.

When does demand for serrapeptase peak?

Demand is steady year-round — the busiest month runs 1.2× the quietest.

What does it cost to enter the serrapeptase niche?

Listings span $9.73–$39.03; the average listing price is $22.10 (sweet spot $15–$100). The average incumbent carries 1,393 reviews — the moat a new listing must climb.

serrapeptase

Worth a look

Shows low returns (0.0%), but a failed launch gate (market size, growth, or returns) keeps it on the watch list.

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Avg price

Great$22.10

avg listing price — sweet spot $15–$100

Conversion

Great9.0%

search→purchase rate — share of searches ending in a sale

Price range

Great$9.73–$39.03

cheapest to priciest tracked listing — scored on the share inside $15–$100

Market size

Good$652K

$652K/yr · 326K searches

Review moat

Good1,393.35

avg incumbent reviews — the moat a new listing must climb

Brand share

Good74%

top-5 brand share — brands hold most of the demand

Quality gap

Okay4.5★

avg incumbent rating — lower means beatable quality

Competition

Okay67%

top-5 click share — leaders hold, buyers still browse

Growth

Bad-6.8%

90-day search growth — must beat 0% to launch

According to Flapen's Amazon United States niche tracking, serrapeptase is a $652K/yr Amazon United States market (326K searches/yr). The top 5 brands hold 74% of demand. Verdict: Worth a look — 56/100.

Data updated Jul 11, 2026 · scored weekly · How we score niches

serrapeptase market data

Units sold / yr: 30K–40K; avg 1,500–2,000/product
Revenue / yr: $663K–$884K; units × avg price
Conversion rate: 9.0%
Avg BSR: #607
Page quality: 0%
Prime: 100%
Sponsored: 94%
Out of stock: 0.4%
Avg brand age: 83 months
Avg seller age: 170 days

Competition & brand share

The top 5 products take 67% of clicks — established leaders, but buyers still shop beyond them.

Brands

15 falling

Sellers

Top-5 brand share

74%

Top 20: 100%

Top-5 click share

67%

Top 20: 100%

Open market

20%

Double Wood Supplements27%
Doctor's BEST23%
Vitamatic9%
Nutricost8%
NOW Foods7%
MARYRUTH'S5%

Demand & seasonality

Weekly Amazon search volume, last 104 weeks — -6.8% search growth over the last 90 days.

No pronounced peak months · busiest ÷ quietest = 1.2×

Open Trend

Top serrapeptase search terms

serrapeptase206K/yr -7.0%8.4% conv.
serrapeptase supplement62K/yr -3.8%7.4% conv.
serapeptase supplement25K/yr -13.6%9.0% conv.
serapeptase9K/yr -7.2%8.2% conv.
serrapeptase enteric-coated4K/yr +34.3%5.8% conv.
enteric serrapeptase3K/yr +44.2%0.7% conv.
serrapeptase 1200007K/yr -33.0%7.1% conv.
serratiopeptidase5K/yr -16.1%6.0% conv.
serrapaptase4K/yr -34.1%5.9% conv.

All search terms

Top serrapeptase products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 17 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Serrapeptase 240 000 SPU Max Potency (120 Veggie Capsules) Proteolytic Enzyme for Sinus Respiratory and Joint Health (Non-GMO Gluten Free Vegetarian Safe) by Double Wood

Double Wood Supplements$19.564.5★1,270 rev

Doctors Best Serrapeptase Supplement for Men & Women - Proteolytic Enzyme for Sinus & Immune Health Support 120 000 SPU per Veggie Capsule High Potency Formula Non-GMO Vegan - 90 Veg Caps

Doctor's BEST$28.614.4★9,702 rev

Nutricost Serrapeptase 120 000 SPU 120 Capsules - Gluten Free Non-GMO and Vegetarian Friendly

Nutricost$17.664.6★450 rev

NOW Foods Supplements Serrapeptase 60 000 Units of Activity Promotes Respiratory Health and Immune Function* 60 Veg Capsules

NOW Foods$14.054.6★777 rev

Vitamatic Serrapeptase 240 000 SPU Servings 120 Delayed Released Capsules - Enteric Coated - Non-GMO- Made in the USA (120 Count (Pack of 1))

Vitamatic$14.594.5★345 rev

Newest

by launch date

Potent Nattokinase 4000 FU Serrapeptase 240000 SPU Lumbrokinase 2000 FU Supplement - Proteolytic Enzymes Capsules for Energy Support Digestion Detox Cognition & Gut Health for Men & Women

Etta Vita$29.35673 rev

2y ago

Nutramedix Serrapeptase Supplement - Proteolytic Enzymes for Digestion + Inulin - Made to Support Digestive Health Support - Gluten Soy and Dairy-Free (60 Capsules)

NutraMedix$35.36180 rev

2y ago

Vitamatic Serrapeptase 240 000 SPU Servings 120 Delayed Released Capsules - Enteric Coated - Non-GMO- Made in the USA (120 Count (Pack of 1))

Vitamatic$14.59345 rev

2y ago

Vitamatic Serrapeptase 240 000 SPU Servings 120 Delayed Released Capsules - Enteric Coated - Non-GMO- Made in the USA (120 Count (Pack of 2))

Vitamatic$21.32114 rev

2y ago

Best Naturals Serrapeptase 120000 SPUs 90 Vegetarain Capsules - Supports Sinus Health

Best Naturals$9.73156 rev

2y ago

What buyers say about serrapeptase

What buyers praise and complain about, mined from review topics.

What buyers love

Quality-Overall24%

“It feels like good quality and arrived quickly”

Value For Money8%

“good price”

Vitamin7%

“it boosts the vitamins So they can absorb faster”

Efficiency6%

“Works well”

Advertised Vs Actual Product5%

“As advertised”

Inflammation3%

“it definitely helps with inflammation”

Regulates Digestion3%

“Sure helps with my digestion issues”

Joint Pain3%

“Helps with joint pain”

Heart Health3%

“Reduces carotid buildup”

Sinus Relief3%

“I use serrapeptase to treat sinus infection and do recommend”

What buyers complain about

Ingredients-Overall14%

“Also milk and soy are additives they are not supposed to be included in serrapeptase”

Dosage8%

“After 2 doses it literally destroyed my digestive system”

Regulates Digestion7%

“After 2 doses it literally destroyed my digestive system”

Functionality-Overall6%

“Did not work for me”

Taste-Overall5%

“This item 'tastes' like mold”

Side Effects4%

“causing great pain”

Ease Of Use3%

“Not usable”

Adhesion/Stickiness3%

“adhesions are loosening up”

Inflammation3%

“not for inflammation or scar tissue”

Advertised Vs Actual Product3%

“Very deceiving marketing”

Top return reasons

Sensitivity-Overall50%

Ingredients-Overall25%

Advertised Vs Actual Product25%

Common questions

Is serrapeptase profitable to sell on Amazon United States?: The niche generates $652K/yr across 17 tracked products. 90-day search growth is -6.8%. Flapen's verdict: Worth a look (56/100).
How competitive is the serrapeptase niche?: 15 brands and 30 sellers compete. The top 5 products take 67% of clicks and top 5 brands hold 74% of demand.
What do buyers complain about in serrapeptase?: Top complaints mined from reviews: Ingredients-Overall, Dosage, Regulates Digestion. The return rate is 0.0%.
When does demand for serrapeptase peak?: Demand is steady year-round — the busiest month runs 1.2× the quietest.
What does it cost to enter the serrapeptase niche?: Listings span $9.73–$39.03; the average listing price is $22.10 (sweet spot $15–$100). The average incumbent carries 1,393 reviews — the moat a new listing must climb.

serrapeptase

serrapeptase market data

Competition & brand share

Demand & seasonality

Top serrapeptase search terms

Top serrapeptase products on Amazon

Top sellers

Newest

Trending

What buyers say about serrapeptase

What buyers love

What buyers complain about

Top return reasons

Common questions

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