Protease
MaybeAn estimated 0.0% of orders come back. But shoppers spend an estimated $51K a year here, so Protease is a Maybe.
- Flapen Score
- 50 / 100Top 44% of 14,768 Health & Household niches · +1 vs the category median of 4950
- Market size
- $51K/yr40K searches / yr
- 90-day growth
- +9.6%search demand this quarter
- Competition
- 51%top-5 click share · 17 brands · 586 sellers
Flapen Score
Protease against its category
The dotted line is the Health & Household average. Past it, Protease is stronger. Inside it, weaker.
Market
The Protease market on Amazon at a glance
Shoppers on Amazon United States searched for Protease 40K times last year and spent an estimated $51K. The top 5 brands take 72% of clicks. Flapen scores it 50 out of 100, a Maybe.
01 · Demand
An estimated 3.9% of those searches ended in a purchase.
Shoppers searched for this 40K times in the last 12 months. That counts every search on Amazon United States for this niche's terms. An estimated 3.9% of those searches ended in a purchase. Searches in the last 90 days moved +9.6% against the 90 days before. Searches, conversion and average price together put the market at an estimated $51K a year.
- Searches, last 12 months
- 40K
- Growth, 90 days vs prior 90
- +9.6%
- Conversion, latest week
- 3.9%
- Market size, estimated
- $51Ka year
- Peak month
- August1.2× the quietest month
- Top search term
- protease16K searches a year
02 · Price
A sale here is worth $32.75.
Listings sell for $32.75 on average, from $9.96 to $86.87. Amazon reports units sold in ranges. This niche sold 2K to 2K a year. The average listing sells 0 to 100 of them. At $32.75 that is $0 to $3K a year per listing.
- Average price
- $32.75inside the $15 to $100 sweet spot
- Price range
- $9.96–$86.87
- Amazon United States median price
- $24.38across 115,062 niches
- Units sold a year
- 2K–2K
- Units per listing a year
- 0–100
- Revenue per listing a year
- $0–$3K
- Returns
- 0.0%of orders · Amazon United States median 2.1%
03 · Entry bar
The bar here is reviews.
81% of listings pay for placement with sponsored ads. 96% ship with Prime. On an average day, 0.0% of listings are out of stock. The average listing ranks #713 within Enzymes. It carries 3,641 reviews at 4.54 stars, so a new listing needs social proof before a better product.
- Sponsored listings
- 81%
- Prime listings
- 96%
- Out of stock, average day
- 0.0%
- Average rank
- #713in Enzymes
- Average rating
- 4.54 starsAmazon United States average 4.42 stars
- Average reviews
- 3,641per listing
- Listings tracked
- 27
04 · Newcomers
0 of last year's 1 launches cleared the first-year sales bar.
1 products launched here in the last 12 months. 0 of them cleared the first-year sales bar, our mark for a successful launch. The brands on the shelf have sold for 99 months on average, so the names here are established.
- Launched, last 12 months
- 1
- Successful launches
- 0Amazon's first-year sales bar
- Average brand age
- 99 months
Products
Top Protease products & what they sell for
The products selling here, as shoppers see them on Amazon. Shelf share and sales are our estimates.
Prices and ratings read from Amazon on Jul 26, 2026. The live listing can differ.
Top sellers
by estimated 90-day click share
TRANSFORMATION THE GENESIS OF GOOD HEALTH Protease 375K Enzyme Blend Supplement High-Potency Formula for Protein Absorption & Gut Health Advanced Enzym Support Non-GMO 60 Capsules
- Price
- $45.14
- Rating
- 4.4/5
- Reviews
- 205
- Age
- 15y ago

NOW Supplements Pancreatin 10X 200 mg with naturally occurring Protease (Protein Digesting) Amylase (Carbohydrate Digesting) and Lipase (Fat Digesting) Enzymes 100 Capsules
- Price
- $11.86
- Rating
- 4.6/5
- Reviews
- 4,659
- Age
- 17y ago

Physicians CHOICE Digestive Enzymes for Bloating & Digestion - Fast-Acting 16 Enzyme Formula with Organic Prebiotics & Probiotics for Gut & Digestive Health - Meal Time Discomfort Relief - 60 CT
- Price
- $19.08
- Rating
- 4.5/5
- Reviews
- 18,747
- Age
- 3y ago

Ness Protease | Single Enzyme Digestive Supplement | Supports Protein Digestion | 180 Vegetarian Capsules
- Price
- $25.16
- Rating
- 4.4/5
- Reviews
- 39
- Age
- 17y ago

TRANSFORMATION THE GENESIS OF GOOD HEALTH Enzymes - Protease Digestive Supplement Advanced Formula Supports Healthy Digestion Immunity Nutrient Absorption Improve Tolerance On an Empty Stomach
- Price
- $86.87
- Rating
- 4.5/5
- Reviews
- 209
- Age
- 14y ago
Trending
estimated 90-day click momentum
Digestive Enzymes Supplement for Men High Potency Pancreatin 4X Formula with Amylase Protease & Lipase Enzymes for Digestion Bloating Relief & Gut Health 50 Capsules
- Price
- $16.49
- Rating
- 4.6/5
- Reviews
- 27
- Age
- 3mo ago

Enzymedica Digest Complete - Helps Gas & Bloating - 90 Caps
- Price
- $27.77
- Rating
- 4.7/5
- Reviews
- 1,146
- Age
- 18y ago

Enzymedica Lypo Gold - Protease Amylase & Lipase Digestive Enzymes for Women & Men Enzyme Supplement for Fat Digestion Gut Health & Gallbladder Support Helps Gas & Bloating Gluten Free - 60 Caps
- Price
- $22.37
- Rating
- 4.4/5
- Reviews
- 1,840
- Age
- 17y ago

BSG Amylase Enzyme Formula 1 lb
- Price
- $13.06
- Rating
- 4.7/5
- Reviews
- 1,281
- Age
- 9y ago

Nutricost Digestive Enzymes (620mg) 120 Capsules
- Price
- $19.31
- Rating
- 4.6/5
- Reviews
- 1,239
- Age
- 8y ago
Newest
by launch date
Digestive Enzymes Supplement for Men High Potency Pancreatin 4X Formula with Amylase Protease & Lipase Enzymes for Digestion Bloating Relief & Gut Health 50 Capsules
- Price
- $16.49
- Rating
- 4.6/5
- Reviews
- 27
- Age
- 3mo ago

TRANSFORMATION THE GENESIS OF GOOD HEALTH Protease 375K Enzyme Blend Supplement High-Potency Formula for Protein Absorption & Gut Health Advanced Enzym Support for Nuttrient Absorption Non-GMO 120
- Price
- $82.21
- Rating
- 4.4/5
- Reviews
- 205
- Age
- 2y ago

Physicians CHOICE Digestive Enzymes for Bloating & Digestion - Fast-Acting 16 Enzyme Formula with Organic Prebiotics & Probiotics for Gut & Digestive Health - Meal Time Discomfort Relief - 60 CT
- Price
- $19.08
- Rating
- 4.5/5
- Reviews
- 18,747
- Age
- 3y ago

Digestive Enzymes - 800mg Blend of All 10 Most Essential Digestive and Pancreatic Enzymes (Amylase Lipase Bromelain Lactase Papain Protease Cellulase Maltase Invertase) by Double Wood
- Price
- $18.12
- Rating
- 4.6/5
- Reviews
- 3,836
- Age
- 5y ago

Wonder Laboratories Proteolytic Enzymes | Bromelain Papain Pancreatin Trypsin 550 mg Total with Standardized Amylase Lipase and Protease 100 Tablets
- Price
- $9.96
- Rating
- 4.6/5
- Reviews
- 787
- Age
- 6y ago
Competition
Competition: brands, sellers & click share
The top 5 products take an estimated 51% of clicks. Leaders hold, but buyers still shop past them.
Brands
17 falling
Sellers
586
Est. top-5 brand share
72%
Top 20: 100%
Est. top-5 click share
51%
Top 20: 93%
Open market
22%
- TRANSFORMATION29%
- NOW Foods19%
- Physician's CHOICE9%
- Pure Encapsulations8%
- NESS7%
- Double Wood Supplements6%
Demand
Protease search demand
Weekly searches over the year, seasonality beneath. Pick a range.
No pronounced peak months · busiest ÷ quietest = 1.2×
Search terms
Top Protease search terms shoppers use
The exact words shoppers type, with estimated yearly volume, growth, and conversion.
- protease16K/yr
- protease enzyme supplement13K/yr
- protease enzyme4K/yr
- amylase lipase protease enzyme3K/yr
- protease enzymes4K/yr
Reviews and returns
What reviews say buyers love and hate about Protease
We read the reviews and the return reasons for every product selling here.
“they dont work very well”
Every topic
Every topic buyers talk about, one row each.
Red shows the share of negative reviews and green the share of positive reviews, biggest topic first. Open a row to read what they wrote.
19 topics
Keep looking
Related niches
Niches in the same category that score near this one. Research these next.
Best Flapen score
The highest-scoring niches we track right now, across every category.
FAQ
Common Protease questions
Answered from the same tracked data.
Figures on this page are estimates modeled from public Amazon pages and third-party keyword data. Amazon does not supply them, and no connected seller's data is used. How we handle Amazon data









