Is progesterone profitable to sell on Amazon United States?

The niche generates $351K/yr across 17 tracked products. 3 of 3 products launched in the last 360 days are still selling. 90-day search growth is -4.9%. Flapen's verdict: Worth a look (54/100).

How competitive is the progesterone niche?

16 brands and 39 sellers compete. The top 5 products take 66% of clicks and top 5 brands hold 66% of demand.

What do buyers complain about in progesterone?

Top complaints mined from reviews: Functionality-Overall, Side Effects, Smell. The return rate is 0.2%.

When does demand for progesterone peak?

Demand is steady year-round — the busiest month runs 1.7× the quietest.

What does it cost to enter the progesterone niche?

Listings span $11.37–$69.39; the average listing price is $29.89 (sweet spot $15–$100). The average incumbent carries 902 reviews — the moat a new listing must climb.

progesterone

Worth a look

Shows low returns (0.2%), but soft demand (-4.9% this quarter) keeps it on the watch list.

Returns

Incredible0.2%

return rate — above 5% kills the launch gate

Avg price

Incredible$29.89

avg listing price — sweet spot $15–$100

Price range

Great$11.37–$69.39

cheapest to priciest tracked listing — scored on the share inside $15–$100

Brand share

Good66%

top-5 brand share — brands hold most of the demand

Quality gap

Good4.4★

avg incumbent rating — lower means beatable quality

Review moat

Good902.12

avg incumbent reviews — the moat a new listing must climb

Market size

Good$351K

$351K/yr · 639K searches

Competition

Okay66%

top-5 click share — leaders hold, buyers still browse

Growth

Bad-4.9%

90-day search growth — must beat 0% to launch

Conversion

Bad1.8%

search→purchase rate — share of searches ending in a sale

According to Flapen's Amazon United States niche tracking, progesterone is a $351K/yr Amazon United States market (639K searches/yr). The top 5 brands hold 66% of demand. Verdict: Worth a look — 54/100.

Data updated Jul 12, 2026 · scored weekly · How we score niches

progesterone market data

Units sold / yr: 13K–15K; avg 250–500/product
Revenue / yr: $374K–$448K; units × avg price
Conversion rate: 1.8%
Avg BSR: #362
Page quality: 0%
Prime: 100%
Sponsored: 76%
Out of stock: 3.4%
Avg brand age: 64 months
Avg seller age: 147 days

Competition & brand share

The top 5 products take 66% of clicks — established leaders, but buyers still shop beyond them.

Brands

16 flat

Sellers

Top-5 brand share

66%

Top 20: 100%

Top-5 click share

66%

Top 20: 100%

Open market

29%

Proov24%
Life Extension16%
SMNutrition9%
Equilife9%
Double Wood Supplements8%
Gaia Herbs PRO5%

Demand & seasonality

Weekly Amazon search volume, last 104 weeks — -4.9% search growth over the last 90 days.

No pronounced peak months · busiest ÷ quietest = 1.7×

Open Trend

Top progesterone search terms

progesterone311K/yr -0.5%1.7% conv.
progesterone supplements for women114K/yr -0.9%2.3% conv.
progesterone for women25K/yr +0.9%2.7% conv.
progesterona para mujer16K/yr +80.1%0.9% conv.
progesterona30K/yr -19.6%0.7% conv.
progesterone supplements23K/yr -48.7%1.4% conv.
progesterone pills14K/yr -8.8%2.0% conv.
natural progesterone10K/yr +21.8%1.1% conv.
progesterona natural slim9K/yr +47.6%0.5% conv.
micronized progesterone10K/yr -7.8%0.5% conv.

All search terms

Top progesterone products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 17 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Proov - Luteal Love - Promotes Progesterone Production Cortisol & Hormone Balance for Women -Fertility & Menopause Support -Vitex Ashwagandha Maca -Herbal Supplement -New Packaging - 1 Month Supply

Proov$29.074.3★580 rev

Life Extension Pregnenolone - Hormone Balance Supplement for Healthy Hormone Levels 100 mg - Hormone Balance Memory Focus Cognitive Health - Gluten-Free Non-GMO 100 Capsules

Life Extension$12.894.6★4,017 rev

Advanced Progesto-Life Balancing Skin Cream for Women 4oz | Cosmetic Skin Cream with 2000mg of Progesterone per Container | Dermatologist-Tested Hypoallergenic & Cruelty-Free | 96 Applications

SMNutrition$29.214.4★398 rev

Equilife Herbal Progesterone Support for Women with Black Cohosh & Passion Flower -Ease Menopausal Symptoms Promote Healthier Cycles Boost Mood Vegan Non-GMO Gluten Dairy & Soy Free 90 Capsules

Equilife$44.764.4★142 rev

Pregnenolone 100mg per Serving (Converted to Progesterone to Boost Progesterone Levels) - Third Party Tested - 120 Capsules (50mg per Capsule) Non-GMO by Double Wood

Double Wood Supplements$19.824.4★1,442 rev

Newest

by launch date

Olidiva Progesto+ Cream | Bioidentical Hormone Support & Synthetic Progesterone Free | For PMS & Menopausal Comfort 100g / 3.4 oz (3 Month Supply)

Olidiva$24.3187 rev

6mo ago

Advanced Progesto-Life Balancing Skin Cream for Women 4oz | Cosmetic Skin Cream with 2000mg of Progesterone per Container | Dermatologist-Tested Hypoallergenic & Cruelty-Free | 96 Applications

SMNutrition$29.21398 rev

11mo ago

Progesterone Balance Cream for Women - Infused with MSM Aloe Vera Coconut Oil & Shea Butter | 3.4 fl oz Gluten-Free Non-GMO Vegan-Friendly | Daily Skin Comfort & Balanced-Looking Skin Support

ZODENIS$17.1881 rev

11mo ago

Olidiva Wild Yam Cream Hormone Balance for Women | Natural Estrogen & Progesterone Free Hormone Support | For PMS & Menopausal Comfort | Day & Night Cream for Hot Flashes & Night Sweats (3.4 oz)

Olidiva$22.72343 rev

2y ago

BIOLABS PRO Progest MAXX Progesterone Oil Natural Bioidentical Progesterone for Women Hot Flashes & Menopause Support 2oz Bottle - Six Month Supply

BIOLABS PRO$69.39137 rev

2y ago

What buyers say about progesterone

What buyers praise and complain about, mined from review topics.

What buyers love

Quality-Overall12%

“Great product, great branding”

Hormonal Balance9%

“it has got my hormones in check”

Absorbency6%

“highly absorbent”

Smell5%

“fresh scent”

Efficiency5%

“the product seems effective”

Value For Money5%

“Great value”

Sleep Quality5%

“I'm sleeping better”

Ease Of Use4%

“Easy to use”

Menstrual Issues4%

“Helps with menopause symptoms”

Ease Of Application3%

“Easy Application”

What buyers complain about

Functionality-Overall13%

“Problem is 90% of the time I couldnt get anything to come out”

Side Effects7%

“Made me sick as crap”

Smell5%

“Smells horrible”

Ingredients-Overall4%

“beware of the other herbs in it not advertised”

Value For Money4%

“so the cost isn't sufficient for my value needs”

Allergies4%

“Caused painful rash”

Advertised Vs Actual Product3%

“False Advertising”

Dosage3%

“be careful and maybe start with lower dosage”

Ease Of Use3%

“I simply can't use it”

Quality-Overall2%

“without a perfect rating”

Top return reasons

Functionality-Overall28%

Motor Power23%

Advertised Vs Actual Product10%

Value For Money4%

Leak-Proof4%

Ingredients-Overall4%

Smell4%

Certifications3%

Texture/Consistency-Overall2%

Side Effects2%

Common questions

Is progesterone profitable to sell on Amazon United States?: The niche generates $351K/yr across 17 tracked products. 3 of 3 products launched in the last 360 days are still selling. 90-day search growth is -4.9%. Flapen's verdict: Worth a look (54/100).
How competitive is the progesterone niche?: 16 brands and 39 sellers compete. The top 5 products take 66% of clicks and top 5 brands hold 66% of demand.
What do buyers complain about in progesterone?: Top complaints mined from reviews: Functionality-Overall, Side Effects, Smell. The return rate is 0.2%.
When does demand for progesterone peak?: Demand is steady year-round — the busiest month runs 1.7× the quietest.
What does it cost to enter the progesterone niche?: Listings span $11.37–$69.39; the average listing price is $29.89 (sweet spot $15–$100). The average incumbent carries 902 reviews — the moat a new listing must climb.