Is ondansetron profitable to sell on Amazon United States?

The niche generates $523K/yr across 9 tracked products. 0 of 1 products launched in the last 360 days are still selling. 90-day search growth is -0.9%. Flapen's verdict: Skip it (43/100).

How competitive is the ondansetron niche?

2 brands and 38 sellers compete. The top 5 products take 82% of clicks and top 5 brands hold 100% of demand.

What do buyers complain about in ondansetron?

Top complaints mined from reviews: Taste-Overall, Functionality-Overall, Acid Regulator/Stomach Ache Relief. The return rate is 0.0%.

When does demand for ondansetron peak?

Demand is steady year-round — the busiest month runs 1.3× the quietest.

What does it cost to enter the ondansetron niche?

Listings span $6.66–$17.02; the average listing price is $11.51 (sweet spot $15–$100). The average incumbent carries 1,971 reviews — the moat a new listing must climb.

Ondansetron

Skip it

Brand-locked demand (top 5 brands take 100% of clicks) — this niche doesn't clear our bar today.

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Conversion

Incredible16.8%

search→purchase rate — share of searches ending in a sale

Market size

Good$523K

$523K/yr · 271K searches

Avg price

Okay$11.51

avg listing price — sweet spot $15–$100

Review moat

Okay1,970.67

avg incumbent reviews — the moat a new listing must climb

Growth

Bad-0.9%

90-day search growth — must beat 0% to launch

Quality gap

Bad4.6★

avg incumbent rating — lower means beatable quality

Price range

Bad$6.66–$17.02

cheapest to priciest tracked listing — scored on the share inside $15–$100

Competition

Bad82%

top-5 click share — a locked-up shelf

Brand share

Bad100%

top-5 brand share — brand-locked demand

Is ondansetron profitable on Amazon?

According to Flapen's Amazon United States niche tracking, ondansetron is a $523K/yr Amazon United States market (271K searches/yr). The top 5 brands hold 100% of demand. Verdict: Skip it — 43/100.

Data updated Jul 11, 2026 · scored weekly · How we score niches

ondansetron market size & sales

Units sold, revenue, conversion and listing quality across the tracked shelf.

Units sold / yr: 40K–50K; avg 3,000–4,000/product
Revenue / yr: $460K–$576K; units × avg price
Conversion rate: 16.8%
Avg BSR: #50
Page quality: 0%
Prime: 100%
Sponsored: 67%
Out of stock: 0.0%
Avg brand age: 75 months
Avg seller age: 152 days

Competition: brands, sellers & click share

The top 5 products capture 82% of clicks — a locked-up shelf that new listings rarely crack.

Brands

2 falling

Sellers

Top-5 brand share

100%

Top 20: 100%

Top-5 click share

82%

Top 20: 100%

Open market

Emetrol92%
Boiron9%

ondansetron demand & seasonality

Weekly Amazon search volume, last 66 weeks — -0.9% search growth over the last 90 days.

No pronounced peak months · busiest ÷ quietest = 1.3×

Open Trend

Top ondansetron search terms shoppers use

The exact queries shoppers type, with yearly volume, growth and conversion.

emetrol95K/yr +1.7%20.4% conv.
emetrol rapid nausea relief63K/yr -10.1%22.6% conv.
ondansetron42K/yr +10.0%0.5% conv.
ondansetron 4 mg23K/yr -18.6%0.0% conv.
emetrol chewables16K/yr +5.5%20.6% conv.
motion calm6K/yr +35.8%17.6% conv.
boiron motion sickness5K/yr +27.8%13.7% conv.
emetrol liquid7K/yr -32.5%20.7% conv.
hylands motion sickness tablets4K/yr +8.4%6.9% conv.
boiron motion calm3K/yr +9.1%21.0% conv.

All search terms

Top ondansetron products & what they sell for

Every tracked product — its share of the shelf, its review moat, and what it sells for.

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 9 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Emetrol Non-Drowsy Nausea Relief - Chewable Medicine for Upset Stomach - Pharmacist Recommended Nausea Relief - Mixed Berry Flavor 60 Tablets

Emetrol$9.854.5★922 rev

Emetrol Non-Drowsy Liquid Nausea Relief - Upset Stomach Medicine - Pharmacist Recommended Nausea Relief - Cherry Flavor - 4fl oz 2 Pack

Emetrol$12.654.7★4,547 rev

Emetrol Non-Drowsy Nausea Relief - Liquid Medicine for Upset Stomach Relief - Pharmacist Recommended Nausea Medicine - Cherry Flavor - 12 fl oz

Emetrol$16.844.7★4,547 rev

Emetrol Non-Drowsy Nausea Relief - Liquid Medicine for Upset Stomach Relief - Pharmacist Recommended Nausea Medicine - Cherry Flavor - 4fl oz

Emetrol$6.664.7★4,547 rev

Emetrol Non-Drowsy Nausea Relief - Chewable Medicine for Upset Stomach - Pharmacist Recommended Nausea Relief - Lemon Flavor 84 Tablets

Emetrol$17.024.8★278 rev

Newest

by launch date

Emetrol Daily Digestive Support Capsules Probiotic Prebiotic & Ginger Supplement for Gut Health Bloating Gas & Nausea Support #1 Pharmacist Recommended Brand 30 Capsules

Emetrol$9.7433 rev

3mo ago

Boiron MotionCalm On The Go Relief for Nausea Vomiting or Dizziness associated with Motion Sickness Due to Travel Amusement Rides and Video Games or VR - Non-Drowsy - 2 Count (160 Pellets)

Boiron$10.8459 rev

1y ago

Emetrol Non-Drowsy Nausea Relief - Liquid Medicine for Upset Stomach Relief - Pharmacist Recommended Nausea Medicine - Cherry Flavor - 12 fl oz

Emetrol$16.844,547 rev

1y ago

Emetrol Non-Drowsy Nausea Relief - Chewable Medicine for Upset Stomach - Pharmacist Recommended Nausea Relief - Mixed Berry Flavor 60 Tablets

Emetrol$9.85922 rev

3y ago

Emetrol Non-Drowsy Nausea Relief - Chewable Medicine for Upset Stomach - Pharmacist Recommended Nausea Relief - Lemon Flavor 84 Tablets

Emetrol$17.02278 rev

3y ago

What reviews say buyers love and hate about ondansetron

What buyers praise and complain about, mined from review topics.

What buyers love

Efficiency15%

“Effective”

Taste-Overall9%

“no funky aftertaste”

Acid Regulator/Stomach Ache Relief9%

“my stomach felt better”

Quality-Overall6%

“Excellent product”

Advertised Vs Actual Product6%

“Works as advertised”

Regulates Digestion5%

“It really helped with the bloating”

Ease Of Use5%

“Simple, Palatable, Effective”

Value For Money5%

“Its affordable”

Ease Of Chewing/Swallowing4%

“Chewable”

Side Effects4%

“No side effects”

What buyers complain about

Taste-Overall18%

“There was no taste, no aftertaste, and honestly no indication that I had taken anything at all”

Functionality-Overall14%

“Doesnt really work”

Acid Regulator/Stomach Ache Relief8%

“Ive been having difficulty with a lot of nausea issues lately”

Side Effects4%

“Unfortunately, this made me extremely nauseous and dizzy for most of the day”

Sweetness4%

“Its inate sweetness MIGHT distract from nausea”

Regulates Digestion4%

“Going from diarrhea to constipation”

Dosage3%

“If not mild will need to do multiple doses”

Value For Money3%

“I was tired of wasting money”

Durability3%

“While these are not designed for long term use”

Ease Of Use2%

“Hard to open”

Common ondansetron questions

Is ondansetron profitable to sell on Amazon United States?: The niche generates $523K/yr across 9 tracked products. 0 of 1 products launched in the last 360 days are still selling. 90-day search growth is -0.9%. Flapen's verdict: Skip it (43/100).
How competitive is the ondansetron niche?: 2 brands and 38 sellers compete. The top 5 products take 82% of clicks and top 5 brands hold 100% of demand.
What do buyers complain about in ondansetron?: Top complaints mined from reviews: Taste-Overall, Functionality-Overall, Acid Regulator/Stomach Ache Relief. The return rate is 0.0%.
When does demand for ondansetron peak?: Demand is steady year-round — the busiest month runs 1.3× the quietest.
What does it cost to enter the ondansetron niche?: Listings span $6.66–$17.02; the average listing price is $11.51 (sweet spot $15–$100). The average incumbent carries 1,971 reviews — the moat a new listing must climb.