nrf2
Skip itBrand-locked demand (top 5 brands take 94% of clicks) — this niche doesn't clear our bar today.
Returns
Incredible0.0%return rate — above 5% kills the launch gate
Review moat
Great206.14avg incumbent reviews — the moat a new listing must climb
Avg price
Great$79.00avg listing price — sweet spot $15–$100
Price range
Okay$22.59–$189.17cheapest to priciest tracked listing — scored on the share inside $15–$100
Conversion
Okay3.4%search→purchase rate — share of searches ending in a sale
Quality gap
Okay4.5★avg incumbent rating — lower means beatable quality
Market size
Okay$219K$219K/yr · 81K searches
Growth
Okay+5.3%90-day search growth — must beat 0% to launch
Competition
Okay70%top-5 click share — leaders hold, buyers still browse
Brand share
Bad94%top-5 brand share — brand-locked demand
According to Flapen's Amazon United States niche tracking, nrf2 is a $219K/yr Amazon United States market (81K searches/yr). The top 5 brands hold 94% of demand. Demand peaks in Oct. Verdict: Skip it — 46/100.
Data updated Jul 25, 2026 · scored weekly · How we score niches
nrf2 market data
- Units sold / yr
- 3K–4K
- avg 100–250/product
- Revenue / yr
- $237K–$316K
- units × avg price
- Conversion rate
- 3.4%
- Avg BSR
- #5,243
- Page quality
- 0%
- Prime
- 93%
- Sponsored
- 86%
- Out of stock
- 2.1%
- Avg brand age
- 55 months
- Avg seller age
- 152 days
Competition & brand share
The top 5 products take 70% of clicks — established leaders, but buyers still shop beyond them.Brands
8 rising
Sellers
9
Top-5 brand share
94%
Top 20: 100%
Top-5 click share
70%
Top 20: 100%
Open market
4%
- LifeVantage70%
- Pure Encapsulations9%
- Xontravix8%
- Superior Formulas LLC4%
- Pure Therapro Rx3%
- Allergy Research Group2%
- Open — no brand owns it (2 brands, 4%)
Demand & seasonality
Weekly Amazon search volume, last 104 weeks — +5.3% search growth over the last 90 days.Peak months: Oct · busiest ÷ quietest = 1.6×
Top nrf2 search terms
- protandim23K/yr
- nrf218K/yr
- protandim nrf215K/yr
- protandim nrf2 synergizer lifevantage7K/yr
- lifevantage6K/yr
- nrf2 supplement7K/yr
- nrf2 activator4K/yr
- protandim supplement2K/yr
Top nrf2 products on Amazon
Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.
All 14 tracked products in this niche — three views at once, no toggling.
Top sellers
by 90-day click share
Protandim Nrf2 Synergizer Cellular Health & Antioxidant Support Supplement Healthy Aging Formula with Turmeric Ashwagandha Green Tea & Milk Thistle 30 Capsules
LifeVantage$76.604.5★818 rev

Protandim Nrf2 Synergizer Cellular Health & Antioxidant Support Supplement Healthy Aging Formula with Turmeric Ashwagandha Green Tea & Milk Thistle 30 Capsules
LifeVantage$186.794.5★818 rev

LifeVantage Protandim NRF1 Synergizer NRF1 Activator for Cellular Health Function ATP Production Mitochondrial Supplements for Energy Vitality & Aging Support 60 Capsules
LifeVantage$76.404.3★122 rev

Pure Encapsulations Nrf2 Detox | Nrf2 and Detoxification Support* | 60 Capsules
Pure Encapsulations$62.554.7★136 rev

LifeVantage Protandim Dual Synergizer NRF1 (60 Caps) + Nrf2 (30 Caps) Activators Healthy Aging Antioxidant Cellular Energy Boost Heart Health Ashwagandha Turmeric CoQ10
LifeVantage$128.134.4★258 rev
Newest
by launch date
NRF1 & NRF2 Supplement 1500mg | Dual Activator with CoQ10 Curcumin Trans Resveratrol & Ashwagandha | Antioxidant for Oxidative Stress Wellness Aging & Cellular Energy | 60 Capsules (2 Bottle)
Xontravix$34.0819 rev

NRF1 & NRF2 Supplement 1500mg | Dual Activator with CoQ10 Curcumin Trans Resveratrol & Ashwagandha | Antioxidant for Oxidative Stress Wellness Aging & Cellular Energy | 60 Capsules (1 Bottle)
Xontravix$22.5915 rev

NRF2 COMPLEX Supplement Capsules (120 Capsules) 4 Months Supply
Florida Herbal Pharmacy$40.9928 rev

Superior Formulas Nrf2 Activator Supplement Antioxidant Support for Cellular Health Healthspan and Longevity Helps Reduce Oxidative Stress 60 Capsules Made in USA Non-GMO
Superior Formulas LLC$43.3239 rev

NRF2 Activator Antioxidant Supplements for Cell Vitality by Waybest 60 Capsules(1 Bottle) Reduce Oxidative Stress by 40% in 30 Days Blend of 5 Herbal Phytonutrients Ingredients Support Immune Skin DNA
EBAT$38.4750 rev
Trending
90-day click momentum
LifeVantage Protandim NRF1 Synergizer NRF1 Activator for Cellular Health Function ATP Production Mitochondrial Supplements for Energy Vitality & Aging Support 60 Capsules
LifeVantage$76.404.3★

Allergy Research Group ARG Nrf2 Renew - Sulforaphane Supplement - NRF2 Activator with Antioxidant & Cellular Support - Botanical Formula - 60 Servings - 120 Capsules
Allergy Research Group$72.494.7★

LifeVantage Protandim NAD Synergizer NAD Supplement for Energy Mood Healthy Aging Support Sirtuin Activation Cellular Energy & Vascular Support Remove Cellular Waste 60 Capsules
LifeVantage$76.564.4★

NRF2 COMPLEX Supplement Capsules (120 Capsules) 4 Months Supply
Florida Herbal Pharmacy$40.994.4★

Pure Encapsulations Nrf2 Detox | Nrf2 and Detoxification Support* | 60 Capsules
Pure Encapsulations$62.554.7★
What buyers say about nrf2
What buyers praise and complain about, mined from review topics.What buyers love
“Since Ive taking this supplement I feel with more energy”
“doesnt interfere with other supplements I take”
“Seems good quality”
“doesnt interfere with other supplements I take”
“have not had any negative reactions with any of the other supplements I take”
“The ingredients include alot of the basics for good health”
“Inexpensive compared to competitive brands of Nerf1 and Nerf2”
“For whatever reason protandim was the only product out of approximately 10 that I tried that would reduce inflammation”
“This is my go to for better sleep, skin, and energy”
“Cellular health and antioxidant protection”
What buyers complain about
“Waste of money”
“And stress is what causes so many health issues”
“I was also experiencing severe nerve pain in my arms”
“No effects, positive or negative, felt from consuming these products”
“Blood test showed my cortisol level at 47”
“poor sleep”
Common questions
- Is nrf2 profitable to sell on Amazon United States?
- The niche generates $219K/yr across 14 tracked products. 1 of 2 products launched in the last 360 days are still selling. 90-day search growth is +5.3%. Flapen's verdict: Skip it (46/100).
- How competitive is the nrf2 niche?
- 8 brands and 9 sellers compete. The top 5 products take 70% of clicks and top 5 brands hold 94% of demand.
- What do buyers complain about in nrf2?
- Top complaints mined from reviews: Value For Money, Stress/Anxiety, Pain Relief-Overall. The return rate is 0.0%.
- When does demand for nrf2 peak?
- Demand peaks in Oct; the busiest month runs 1.6× the quietest.
- What does it cost to enter the nrf2 niche?
- Listings span $22.59–$189.17; the average listing price is $79.00 (sweet spot $15–$100). The average incumbent carries 206 reviews — the moat a new listing must climb.