Is nattokinase profitable to sell on Amazon United States?

The niche generates $5.7M/yr across 35 tracked products. 7 of 7 products launched in the last 360 days are still selling. 90-day search growth is +7.2%. Flapen's verdict: Launch it (73/100).

How competitive is the nattokinase niche?

27 brands and 62 sellers compete. The top 5 products take 41% of clicks and top 5 brands hold 54% of demand.

What do buyers complain about in nattokinase?

Top complaints mined from reviews: Dosage, Ingredients-Overall, Value For Money. The return rate is 0.0%.

When does demand for nattokinase peak?

Demand peaks in Mar–Apr–May; the busiest month runs 2.2× the quietest.

What does it cost to enter the nattokinase niche?

Listings span $9.57–$80.03; the average listing price is $28.04 (sweet spot $15–$100). The average incumbent carries 1,446 reviews — the moat a new listing must climb.

Nattokinase

Launch it

A $5.7M/yr market growing +7.2% this quarter with returns at 0.0% — clears our launch bar.

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Market size

Incredible$5.7M

$5.7M/yr · 2.1M searches

Avg price

Incredible$28.04

avg listing price — sweet spot $15–$100

Price range

Great$9.57–$80.03

cheapest to priciest tracked listing — scored on the share inside $15–$100

Conversion

Great9.5%

search→purchase rate — share of searches ending in a sale

Brand share

Great54%

top-5 brand share — no brand owns this niche

Competition

Good41%

top-5 click share — leaders hold, buyers still browse

Review moat

Good1,445.86

avg incumbent reviews — the moat a new listing must climb

Quality gap

Okay4.5★

avg incumbent rating — lower means beatable quality

Growth

Okay+7.2%

90-day search growth — must beat 0% to launch

Signals No Dominant Brand

Is nattokinase profitable on Amazon?

According to Flapen's Amazon United States niche tracking, nattokinase is a $5.7M/yr Amazon United States market (2.1M searches/yr). The top 5 brands hold 54% of demand. Demand peaks in Mar–Apr–May. Verdict: Launch it — 73/100.

Data updated Jul 26, 2026 · scored weekly · How we score niches

nattokinase market size & sales

Units sold, revenue, conversion and listing quality across the tracked shelf.

Units sold / yr: 200K–250K; avg 6,000–8,000/product
Revenue / yr: $5.6M–$7.0M; units × avg price
Conversion rate: 9.5%
Avg BSR: #700
Page quality: 0%
Prime: 100%
Sponsored: 94%
Out of stock: 0.0%
Avg brand age: 56 months
Avg seller age: 149 days

Competition: brands, sellers & click share

The top 5 products take 41% of clicks — established leaders, but buyers still shop beyond them.

Brands

27 rising

Sellers

Top-5 brand share

54%

Top 20: 94%

Top-5 click share

41%

Top 20: 86%

Open market

41%

Double Wood Supplements19%
Micro Ingredients12%
Nutricost10%
Doctor's BEST8%
Luma Nutrition5%
MEGNETA5%

nattokinase demand & seasonality

Weekly Amazon search volume, last 104 weeks — +7.2% search growth over the last 90 days.

Peak months: Mar, Apr, May · busiest ÷ quietest = 2.2×

Open Trend

Top nattokinase search terms shoppers use

The exact queries shoppers type, with yearly volume, growth and conversion.

nattokinase1.2M/yr +34.1%8.1% conv.
nattokinase supplement483K/yr -40.5%7.9% conv.
nattokinase 10000 fu120K/yr -17.1%6.5% conv.
nattokinase 12000 fu35K/yr +91.0%5.1% conv.
nattokinase 4000 fu74K/yr +7.0%11.1% conv.
nattokinase supplement organic78K/yr -37.1%4.9% conv.
nattokinase 2000 fu39K/yr +17.6%9.6% conv.
nattokinase organic22K/yr +55.6%3.7% conv.
organic nattokinase20K/yr +17.8%1.6% conv.
doctors best nattokinase14K/yr +9.0%14.5% conv.

All search terms

Top nattokinase products & what they sell for

Every tracked product — its share of the shelf, its review moat, and what it sells for.

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 24 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Nattokinase Supplement 4 000 FU Servings 120 Capsules (Derived from Japanese Natto) Systemic Enzymes for Cardiovascular and Circulatory Support by Double Wood

Double Wood Supplements$18.994.6★3,538 rev

Nutricost Nattokinase 2 000FU 120 Capsules - Gluten Free Non-GMO Vegetarian Friendly

Nutricost$14.614.7★2,590 rev

Micro Ingredients Nattokinase 10 000 FU Per Serving (Natural Natto Extract) 240 Vegetarian Capsules | with CoQ10 Turmeric Aged Garlic & Pine Bark Extract | Non-GMO Lab Tested cGMP Manufactured

Micro Ingredients$29.604.4★175 rev

Nattokinase Supplement 4 000 FU Servings 240 Capsules (Derived from Japanese Natto) Systemic Enzymes for Cardiovascular and Circulatory Support by Double Wood

Double Wood Supplements$33.054.6★3,538 rev

Micro Ingredients Nattokinase 240 Softgels 200mg (4 000 FU) Per Serving | 7-in-1 Nattokinase Supplement with CoQ10 Bromelain Turmeric Ginger Olive Leaf & White Willow Bark | Non-GMO

Micro Ingredients$28.704.6★517 rev

Newest

by launch date

Ultimate Nattokinase 10800 FU Supplement Natural Support for Circulation & Cardiovascular Health Odorless Fermented Soy Enzyme Easy Daily Routine 60 Capsules

zdiwond$35.22129 rev

4mo ago

MEGNETA Nattokinase Supplement 12 000 FU with Serrapeptase 360 000 sPU Lumbrokinase 10 000 FUV & CoQ10 Multi-Enzyme Formula for Daily Circulatory Digestive & Antioxidant Wellness 100 Capsules

MEGNETA$48.50144 rev

5mo ago

Micro Ingredients Nattokinase 10 000 FU Per Serving (Natural Natto Extract) 240 Vegetarian Capsules | with CoQ10 Turmeric Aged Garlic & Pine Bark Extract | Non-GMO Lab Tested cGMP Manufactured

Micro Ingredients$29.60175 rev

8mo ago

Nattokinase Supplement 4 000 FU Servings 240 Capsules (Derived from Japanese Natto) Systemic Enzymes for Cardiovascular and Circulatory Support by Double Wood

Double Wood Supplements$33.053,538 rev

12mo ago

Gyumolics Nattokinase Supplement 10000FU with Organic Nattokinase Serrapeptase Bromelain Curcumin Vitamin E & Ginseng Movement Comfort 90 Capsules

Gyumolics$20.63467 rev

1y ago

What reviews say buyers love and hate about nattokinase

What buyers praise and complain about, mined from review topics.

What buyers love

Quality-Overall18%

“Excellent Product”

Heart Health8%

“Lowered cholesterol”

Value For Money7%

“Great deal”

Advertised Vs Actual Product6%

“AS DESCRIBED”

Vitamin6%

“it boosts the vitamins So they can absorb faster”

Blood Pressure5%

“Great for my blood pressure”

Ease Of Chewing/Swallowing4%

“Easy swallow, appears to be as advertised”

Efficiency4%

“Effective”

Dosage4%

“effective dosage”

Side Effects4%

“it doesnt give me any side effects I really recommend this product I would been buying this product again”

What buyers complain about

Dosage10%

“Wrong dosage listed”

Ingredients-Overall7%

“Misleading ingredients”

Value For Money6%

“Price too high”

Blood Pressure5%

“it makes my blood pressure go really high”

Heart Health5%

“My cholesterol. bad”

Functionality-Overall4%

“Not effective”

Advertised Vs Actual Product4%

“Completely misleading”

Side Effects3%

“Absolutely horrible intestinal pain that almost had me throwing up”

Quality-Overall3%

“Bad quality control”

Certifications2%

“The seller does not provide a certificate of analysis”

Top return reasons

Side Effects31%

Value For Money15%

Leak-Proof8%

Fever Relief8%

Thin8%

Blood Pressure8%

Joint Pain8%

Certifications8%

Ingredients-Overall4%