Is methylfolate b12 profitable to sell on Amazon United States?

The niche generates $259K/yr across 14 tracked products. 3 of 3 products launched in the last 360 days are still selling. 90-day search growth is -9.6%. Flapen's verdict: Skip it (45/100).

How competitive is the methylfolate b12 niche?

9 brands and 558 sellers compete. The top 5 products take 75% of clicks and top 5 brands hold 94% of demand.

What do buyers complain about in methylfolate b12?

Top complaints mined from reviews: Dosage, Functionality-Overall, Taste-Overall. The return rate is 0.0%.

When does demand for methylfolate b12 peak?

Demand peaks in Jan–Feb–Mar–Sep; the busiest month runs 2.6× the quietest.

What does it cost to enter the methylfolate b12 niche?

Listings span $8.35–$28.54; the average listing price is $18.67 (sweet spot $15–$100). The average incumbent carries 4,325 reviews — the moat a new listing must climb.

Methylfolate B12

Skip it

Brand-locked demand (top 5 brands take 94% of clicks) — this niche doesn't clear our bar today.

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Conversion

Incredible13.1%

search→purchase rate — share of searches ending in a sale

Avg price

Great$18.67

avg listing price — sweet spot $15–$100

Price range

Good$8.35–$28.54

cheapest to priciest tracked listing — scored on the share inside $15–$100

Market size

Okay$259K

$259K/yr · 106K searches

Review moat

Bad4,324.93

avg incumbent reviews — the moat a new listing must climb

Competition

Bad75%

top-5 click share — a locked-up shelf

Growth

Bad-9.6%

90-day search growth — must beat 0% to launch

Quality gap

Bad4.7★

avg incumbent rating — lower means beatable quality

Brand share

Bad94%

top-5 brand share — brand-locked demand

Is methylfolate b12 profitable on Amazon?

According to Flapen's Amazon United States niche tracking, methylfolate b12 is a $259K/yr Amazon United States market (106K searches/yr). The top 5 brands hold 94% of demand. Demand peaks in Jan–Feb–Mar–Sep. Verdict: Skip it — 45/100.

Data updated Jul 28, 2026 · scored weekly · How we score niches

methylfolate b12 market size & sales

Units sold, revenue, conversion and listing quality across the tracked shelf.

Units sold / yr: 15K–20K; avg 1,250–1,500/product
Revenue / yr: $280K–$373K; units × avg price
Conversion rate: 13.1%
Avg BSR: #232
Page quality: 0%
Prime: 100%
Sponsored: 100%
Out of stock: 0.0%
Avg brand age: 79 months
Avg seller age: 169 days

Competition: brands, sellers & click share

The top 5 products capture 75% of clicks — a locked-up shelf that new listings rarely crack.

Brands

9 rising

Sellers

558

Top-5 brand share

94%

Top 20: 100%

Top-5 click share

75%

Top 20: 100%

Open market

Jarrow Formulas61%
Triquetra Health16%
Seeking Health7%
Nutricost6%
Pure Encapsulations4%
Life Extension2%
Open — no brand owns it (3 brands, 4%)

methylfolate b12 demand & seasonality

Weekly Amazon search volume, last 101 weeks — -9.6% search growth over the last 90 days.

Peak months: Jan, Feb, Mar, Sep · busiest ÷ quietest = 2.6×

Open Trend

Top methylfolate b12 search terms shoppers use

The exact queries shoppers type, with yearly volume, growth and conversion.

jarrow methyl b-12 & methyl folate39K/yr -24.1%16.6% conv.
methylfolate b1220K/yr +27.5%6.7% conv.
methyl b12 with l-methylfolate9K/yr -31.1%12.9% conv.
methylated b12 and folate11K/yr +4.6%6.8% conv.
methylated folate and b126K/yr +36.0%7.4% conv.
methyl folate b126K/yr -3.0%6.3% conv.
b12 methylfolate5K/yr +0.7%9.2% conv.
jarrow b12 folate3K/yr +34.5%21.9% conv.
methyl b12 folate4K/yr +0.4%7.9% conv.
jarrow b12 methyl folate chewable3K/yr -62.3%19.7% conv.

All search terms

Top methylfolate b12 products & what they sell for

Every tracked product — its share of the shelf, its review moat, and what it sells for.

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 14 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Jarrow Formulas Methyl B-12 & Methyl Folate Bioactive Vitamin B9 and Vitamin B12 Supplement Supports Cellular Energy Production Healthy Brain Function & Metabolism 60 Chewable Tablets 60 Servings

Jarrow Formulas$28.544.7★2,592 rev

Jarrow Formulas Methyl B-12 & Methyl Folate Bioactive Vitamin B9 & Vitamin B12 Supplement Supports Cellular Energy Production Healthy Brain Function & Metabolism 100 Chewable Tablets 100 Servings

Jarrow Formulas$13.684.6★7,791 rev

L Methyl Folate 15mg Plus Methyl B12 Cofactor High Potency Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms of Vitamin B9 & B12 (60 Capsules 60 Servings)

Triquetra Health$21.674.6★9,407 rev

Seeking Health Methyl B12 with L-Methylfolate - MTHFR Support Supplement - Methylation Support Supplement - Lozenges to Support Brain Health & Energy - 60 Lozenges

Seeking Health$25.444.7★2,664 rev

Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps

Nutricost$11.104.7★154 rev

Newest

by launch date

Sports Research 5-MTHF Methyl Folate w/Methylated B12 90 Count Plantgels

Sports Research$21.3825 rev

4mo ago

Vocks$12.4597 rev

5mo ago

Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps

Nutricost$11.10154 rev

11mo ago

Micro Ingredients L Methylfolate 15mg 240 Softgels | Active 5-MTHF with B6 & Methyl B12 | Methylated Vitamin B9 with Coconut Oil

Micro Ingredients$28.48289 rev

1y ago

L Methyl Folate 15mg Plus Methyl B12 Cofactor Organic Berry Flavor High Potency Liquid Sublingual Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms Vitamin B9 & B12 (1oz)

Triquetra Health$21.875,924 rev

4y ago

What reviews say buyers love and hate about methylfolate b12

What buyers praise and complain about, mined from review topics.

What buyers love

Quality-Overall16%

“Quality and ease of use”

Vitamin10%

“also has essential vitamins”

Taste-Overall9%

“It tastes pretty good”

Energy Level9%

“More energy”

Focus Enhancement6%

“feel like it improves my mood”

Advertised Vs Actual Product6%

“Just as advertised”

Efficiency6%

“Very effective”

Value For Money4%

“Worth Buying”

Ease Of Use3%

“Easy to use”

Dosage3%

“Good combination with the doses I needed”

What buyers complain about

Dosage9%

“This is an extremely high dose. was not aware”

Functionality-Overall7%

“No results”

Taste-Overall7%

“It tastes awful”

Side Effects6%

“Made me sick”

Vitamin5%

“my vitamin b levels were low”

Value For Money4%

“The price is a little high”

Allergies4%

“Allergic”

Quality-Overall4%

“Its not as good as they make it seem”

Sleep Quality3%

“I also couldnt sleep”

Ingredients-Overall2%

“Very disappointed to find this product has xylitol as the first other ingredient”

Top return reasons

Dosage29%

Advertised Vs Actual Product14%

Quality-Overall7%

Side Effects7%

Product Condition7%

Vegan/Organic7%

Color7%

Value For Money7%