Is guaifenesin 400mg profitable to sell on Amazon United States?

The niche generates $91K/yr across 10 tracked products. 90-day search growth is -10.0%. Flapen's verdict: Skip it (35/100).

How competitive is the guaifenesin 400mg niche?

7 brands and 10 sellers compete. The top 5 products take 84% of clicks and top 5 brands hold 95% of demand.

What do buyers complain about in guaifenesin 400mg?

Top complaints mined from reviews: Dosage, Size-Overall, Taste-Overall. The return rate is 0.0%.

When does demand for guaifenesin 400mg peak?

Demand is steady year-round — the busiest month runs 1.4× the quietest.

What does it cost to enter the guaifenesin 400mg niche?

Listings span $5.26–$14.65; the average listing price is $10.34 (sweet spot $15–$100). The average incumbent carries 4,948 reviews — the moat a new listing must climb.

guaifenesin 400mg

Skip it

Prices mostly outside the sweet spot ($5.26–$14.65) — this niche doesn't clear our bar today.

Conversion

Incredible21.5%

search→purchase rate — share of searches ending in a sale

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Avg price

Okay$10.34

avg listing price — sweet spot $15–$100

Quality gap

Okay4.6★

avg incumbent rating — lower means beatable quality

Review moat

Bad4,947.5

avg incumbent reviews — the moat a new listing must climb

Market size

Bad$91K

$91K/yr · 41K searches

Growth

Bad-10.0%

90-day search growth — must beat 0% to launch

Competition

Bad84%

top-5 click share — a locked-up shelf

Brand share

Bad95%

top-5 brand share — brand-locked demand

Price range

Bad$5.26–$14.65

cheapest to priciest tracked listing — scored on the share inside $15–$100

According to Flapen's Amazon United States niche tracking, guaifenesin 400mg is a $91K/yr Amazon United States market (41K searches/yr). The top 5 brands hold 95% of demand. Verdict: Skip it — 35/100.

Data updated Jul 11, 2026 · scored weekly · How we score niches

guaifenesin 400mg market data

Units sold / yr: 8K–10K; avg 750–1,000/product
Revenue / yr: $83K–$103K; units × avg price
Conversion rate: 21.5%
Avg BSR: #171
Page quality: 0%
Prime: 100%
Sponsored: 80%
Out of stock: 16.0%
Avg brand age: 85 months
Avg seller age: 182 days

Competition & brand share

The top 5 products capture 84% of clicks — a locked-up shelf that new listings rarely crack.

Brands

7 flat

Sellers

Top-5 brand share

95%

Top 20: 100%

Top-5 click share

84%

Top 20: 100%

Open market

HEALTH LFE37%
GenCare24%
HealthA2Z20%
ValuMeds10%
Safrel5%
NewVue3%
Open — no brand owns it (1 brand, 2%)

Demand & seasonality

Weekly Amazon search volume, last 104 weeks — -10.0% search growth over the last 90 days.

No pronounced peak months · busiest ÷ quietest = 1.4×

Open Trend

Top guaifenesin 400mg search terms

guaifenesin 400mg21K/yr -10.9%16.7% conv.
mucus relief 400mg16K/yr +1.1%22.2% conv.
guaifenesin 400 mg4K/yr -43.3%14.4% conv.

All search terms

Top guaifenesin 400mg products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 10 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

HEALTH LFE Mucus Relief Guaifenesin Caplets 400 mg Immediate Release Fast Acting Expectorant Thin and Loosens Mucus Relieves Chest Congestion Cough Cold and Flu (Medium 200 Count)

HEALTH LFE$9.904.6★3,317 rev

HealthA2Z Mucus Relief Guaifenesin 400mg 300 Counts Dye Free No Benzene Immediate Release Expectorant

HealthA2Z$14.654.6★6,328 rev

GenCare Mucus Relief Expectorant Guaifenesin 400 mg 200 Tablets Value Pack - Fast Acting Thinning of Mucus for Colds Chest Congestion Flu Coughing and Allergies

GenCare$9.904.6★9,209 rev

ValuMeds Mucus Relief Guaifenesin 400mg (200 Caplets) | Maximum Strength | Mucus Thinning for Colds Chest Congestion Flu Coughing | Expectorant & Decongestant

ValuMeds$8.234.6★4,830 rev

GenCare Mucus Relief Expectorant Guaifenesin 400 mg 300 Tablets Value Pack - Fast Acting Thinning of Mucus for Colds Chest Congestion Flu Coughing and Allergies

GenCare$12.844.6★9,209 rev

Newest

by launch date

NewVue Mucus Relief Guaifenesin 400mg Powerful Expectorant Loosens & Thins Mucus Cough Relief Compare to Mucinex Active Ingredients (Small 300 Count)

NewVue$11.84118 rev

2y ago

HealthA2Z Mucus Relief | Guaifenesin 400mg | Immediate Release | No Benzene | Expectorant (60 Counts)

HealthA2Z$5.266,328 rev

3y ago

HEALTH LFE Mucus Relief Guaifenesin Caplets 400 mg Immediate Release Fast Acting Expectorant Thin and Loosens Mucus Relieves Chest Congestion Cough Cold and Flu (Medium 200 Count)

HEALTH LFE$9.903,317 rev

4y ago

HealthLife Mucus Relief Guaifenesin Caplets 400 mg Immediate Release (300 Count) Fast Acting Expectorant Thin and Loosens Mucus Relieves Chest Congestion Cough Cold and Flu

HEALTH LFE$13.283,317 rev

5y ago

Safrel$9.544,021 rev

5y ago

What buyers say about guaifenesin 400mg

What buyers praise and complain about, mined from review topics.

What buyers love

Value For Money32%

“Great deal”

Efficiency14%

“Works well”

Quality-Overall13%

“This brand seems just as effective as others I have tried”

Cough Relief6%

“Works well for sinus/chest congestion”

Advertised Vs Actual Product5%

“Works as Advertised”

Dosage4%

“I HAVE USED THE 400MG AND IS GOOD ENOUGH FOR ME”

Ease Of Chewing/Swallowing3%

“Very effective, the pill is relatively small compared with other brands and they are shaped well for easy swallowing”

Sleep Quality2%

“Day/Night Time Relief”

Breathability2%

“my breathing is much better”

Cold Relief2%

“a must-have for colds or allergies”

What buyers complain about

Dosage15%

“Incorrect dosage instructions”

Size-Overall11%

“Why is the bottle so big”

Taste-Overall8%

“Tastes horrible”

Functionality-Overall7%

“This product does not help much”

Advertised Vs Actual Product7%

“Not as described”

Acid Regulator/Stomach Ache Relief5%

“My niece has a problem with congestion”

Allergies5%

“Take THAT, allergies”

Ease Of Chewing/Swallowing5%

“Hard To Swallow”

Side Effects4%

“It made me so nauseous that I couldnt take it anymore”

Moist/Dry3%

“Dries up mucus”

Common questions

Is guaifenesin 400mg profitable to sell on Amazon United States?: The niche generates $91K/yr across 10 tracked products. 90-day search growth is -10.0%. Flapen's verdict: Skip it (35/100).
How competitive is the guaifenesin 400mg niche?: 7 brands and 10 sellers compete. The top 5 products take 84% of clicks and top 5 brands hold 95% of demand.
What do buyers complain about in guaifenesin 400mg?: Top complaints mined from reviews: Dosage, Size-Overall, Taste-Overall. The return rate is 0.0%.
When does demand for guaifenesin 400mg peak?: Demand is steady year-round — the busiest month runs 1.4× the quietest.
What does it cost to enter the guaifenesin 400mg niche?: Listings span $5.26–$14.65; the average listing price is $10.34 (sweet spot $15–$100). The average incumbent carries 4,948 reviews — the moat a new listing must climb.