Is folate and b12 supplement profitable to sell on Amazon United States?

The niche generates $793K/yr across 14 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is +11.4%. Flapen's verdict: Worth a look (53/100).

How competitive is the folate and b12 supplement niche?

6 brands and 546 sellers compete. The top 5 products take 65% of clicks and top 5 brands hold 99% of demand.

What do buyers complain about in folate and b12 supplement?

Top complaints mined from reviews: Dosage, Vitamin, Side Effects. The return rate is 0.0%.

When does demand for folate and b12 supplement peak?

Demand peaks in Mar; the busiest month runs 1.8× the quietest.

What does it cost to enter the folate and b12 supplement niche?

Listings span $5.79–$47.51; the average listing price is $21.96 (sweet spot $15–$100). The average incumbent carries 3,921 reviews — the moat a new listing must climb.

folate and b12 supplement

Worth a look

Shows low returns (0.0%), but brand-locked demand (top 5 brands take 99% of clicks) keeps it on the watch list.

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Conversion

Incredible12.1%

search→purchase rate — share of searches ending in a sale

Avg price

Great$21.96

avg listing price — sweet spot $15–$100

Price range

Great$5.79–$47.51

cheapest to priciest tracked listing — scored on the share inside $15–$100

Market size

Good$793K

$793K/yr · 298K searches

Growth

Okay+11.4%

90-day search growth — must beat 0% to launch

Competition

Okay65%

top-5 click share — leaders hold, buyers still browse

Review moat

Okay3,921.29

avg incumbent reviews — the moat a new listing must climb

Quality gap

Bad4.7★

avg incumbent rating — lower means beatable quality

Brand share

Bad99%

top-5 brand share — brand-locked demand

According to Flapen's Amazon United States niche tracking, folate and b12 supplement is a $793K/yr Amazon United States market (298K searches/yr). The top 5 brands hold 99% of demand. Demand peaks in Mar. Verdict: Worth a look — 53/100.

Data updated Jul 28, 2026 · scored weekly · How we score niches

folate and b12 supplement market data

Units sold / yr: 30K–40K; avg 2,000–2,500/product
Revenue / yr: $659K–$878K; units × avg price
Conversion rate: 12.1%
Avg BSR: #276
Page quality: 0%
Prime: 100%
Sponsored: 93%
Out of stock: 0.0%
Avg brand age: 84 months
Avg seller age: 145 days

Competition & brand share

The top 5 products take 65% of clicks — established leaders, but buyers still shop beyond them.

Brands

6 falling

Sellers

546

Top-5 brand share

99%

Top 20: 100%

Top-5 click share

65%

Top 20: 100%

Open market

Pure Encapsulations56%
Life Extension19%
Jarrow Formulas14%
Nutricost7%
Triquetra Health4%
NOW Foods1%

Demand & seasonality

Weekly Amazon search volume, last 100 weeks — +11.4% search growth over the last 90 days.

Peak months: Mar · busiest ÷ quietest = 1.8×

Open Trend

Top folate and b12 supplement search terms

folate and b12 supplement72K/yr +16.0%9.1% conv.
pure encapsulations b1238K/yr +22.1%10.3% conv.
b12 folate35K/yr +5.1%14.7% conv.
pure b1229K/yr +16.4%10.7% conv.
b12 and folate14K/yr +46.2%11.5% conv.
b12 and folate supplement20K/yr -17.3%9.9% conv.
pure vitamin b1213K/yr +12.1%8.7% conv.
b12 folate supplement14K/yr -4.5%12.1% conv.
b12 with folate11K/yr +5.7%8.6% conv.
b12 pure encapsulations9K/yr +1.1%11.0% conv.

All search terms

Top folate and b12 supplement products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 14 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Pure Encapsulations B12 Folate - Energy Supplement to Support Nerves Energy Metabolism & Cognitive Support* - with Vitamin B Folate as Metafolin - 60 Capsules

Pure Encapsulations$21.254.8★3,407 rev

Life Extension BioActive Folate & Vitamin B12 Promotes Heart Brain & GI Tract Health Non-GMO Gluten-Free Vegetarian 90 Capsules

Life Extension$8.354.7★3,684 rev

Jarrow Formulas Methyl B-12 & Methyl Folate Bioactive Vitamin B9 & Vitamin B12 Supplement Supports Cellular Energy Production Healthy Brain Function & Metabolism 100 Chewable Tablets 100 Servings

Jarrow Formulas$13.684.6★7,791 rev

Pure Encapsulations Methylcobalamin 1 000 mcg - Vitamin B12 Supplement to Support Memory & Nerve Health* - Premium Vitamin B12 Capsules - 180 Capsules

Pure Encapsulations$47.514.7★3,267 rev

Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps

Nutricost$11.104.7★154 rev

Newest

by launch date

Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps

Nutricost$11.10154 rev

11mo ago

Pure Encapsulations B12 Folate - Energy Supplement to Support Nerves Energy Metabolism & Cognitive Support* - with Vitamin B Folate as Metafolin - 30 Capsules

Pure Encapsulations$14.143,407 rev

3y ago

Life Extension BioActive Folate & Vitamin B12 150 Vegetarian Capsules - Non GMO Gluten Free Supplement

Life Extension$15.75410 rev

3y ago

L Methyl Folate 15mg Plus Methyl B12 Cofactor High Potency Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms of Vitamin B9 & B12 (60 Capsules 60 Servings)

Triquetra Health$21.679,407 rev

5y ago

Jarrow Formulas Methyl B-12 & Methyl Folate Bioactive Vitamin B9 & Vitamin B12 Supplement Supports Cellular Energy Production Healthy Brain Function & Metabolism 100 Chewable Tablets 100 Servings

Jarrow Formulas$13.687,791 rev

10y ago

What buyers say about folate and b12 supplement

What buyers praise and complain about, mined from review topics.

What buyers love

Quality-Overall20%

“Excellent product”

Vitamin13%

“Excellent vitamin”

Advertised Vs Actual Product8%

“As advertised”

Value For Money7%

“GOOD VALUE”

Energy Level6%

“GREAT ENERGY”

Efficiency6%

“They seem effective”

Taste-Overall5%

“Not unpleasant tasting”

Focus Enhancement3%

“These have helped tremendously with my mood”

Ease Of Chewing/Swallowing3%

“Easy to swallow pill”

Ease Of Use3%

“Easy to use”

What buyers complain about

Dosage10%

“is commonly overdosed on”

Vitamin8%

“Way too much Vitamin B9 and B12”

Side Effects7%

“it did say that this was a side effect”

Functionality-Overall7%

“No results”

Taste-Overall4%

“However, the taste is off”

Value For Money4%

“Waste of money”

Sleep Quality3%

“Did not make me feel any better more tired”

Size-Overall3%

“unfortunately this one just doesnt seem to be a good fit”

Ingredients-Overall3%

“disappointed about the ingredients”

Quality-Overall3%

“Filing formal complaints”

Top return reasons

Product Condition20%

Color10%

Ingredients-Overall10%

Dosage10%

Advertised Vs Actual Product10%

Quality-Overall10%

Value For Money10%

Magnesium10%

Vitamin10%

Common questions

Is folate and b12 supplement profitable to sell on Amazon United States?: The niche generates $793K/yr across 14 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is +11.4%. Flapen's verdict: Worth a look (53/100).
How competitive is the folate and b12 supplement niche?: 6 brands and 546 sellers compete. The top 5 products take 65% of clicks and top 5 brands hold 99% of demand.
What do buyers complain about in folate and b12 supplement?: Top complaints mined from reviews: Dosage, Vitamin, Side Effects. The return rate is 0.0%.
When does demand for folate and b12 supplement peak?: Demand peaks in Mar; the busiest month runs 1.8× the quietest.
What does it cost to enter the folate and b12 supplement niche?: Listings span $5.79–$47.51; the average listing price is $21.96 (sweet spot $15–$100). The average incumbent carries 3,921 reviews — the moat a new listing must climb.