Diphenhydramine
FailPrices span $4.12–$10.33, mostly outside the sweet spot, so Diphenhydramine is a Fail.
- Flapen Score
- 43 / 100Ranks 10,775 of 14,768 Health & Household niches · −6 vs the category median of 4943
- Market size
- $532K/yr533K searches / yr
- 90-day growth
- +0.3%search demand this quarter
- Competition
- 71%top-5 click share · 11 brands · 60 sellers
Flapen Score
Diphenhydramine against its category
The dotted line is the Health & Household average. Past it, Diphenhydramine is stronger. Inside it, weaker.
Market
The Diphenhydramine market on Amazon at a glance
Shoppers on Amazon United States searched for Diphenhydramine 533K times last year and spent an estimated $532K. The top 5 brands take 84% of clicks. Flapen scores it 43 out of 100, a Fail.
01 · Demand
An estimated 12.1% of those searches ended in a purchase.
Shoppers searched for this 533K times in the last 12 months. That counts every search on Amazon United States for this niche's terms. An estimated 12.1% of those searches ended in a purchase. Searches in the last 90 days moved +0.3% against the 90 days before. Searches, conversion and average price together put the market at an estimated $532K a year.
- Searches, last 12 months
- 533K
- Growth, 90 days vs prior 90
- +0.3%
- Conversion, latest week
- 12.1%
- Market size, estimated
- $532Ka year
- Peak month
- May1.3× the quietest month
- Top search term
- diphenhydramine249K searches a year
02 · Price
A sale here is worth $8.24.
Listings sell for $8.24 on average, from $4.12 to $10.33. Amazon reports units sold in ranges. This niche sold 60K to 80K a year. The average listing sells 4,000 to 5,000 of them. At $8.24 that is $33K to $41K a year per listing.
- Average price
- $8.24under the $15 to $100 sweet spot
- Price range
- $4.12–$10.33
- Amazon United States median price
- $24.38across 115,062 niches
- Units sold a year
- 60K–80K
- Units per listing a year
- 4,000–5,000
- Revenue per listing a year
- $33K–$41K
- Returns
- 0.0%of orders · Amazon United States median 2.1%
03 · Entry bar
The bar here is reviews.
80% of listings pay for placement with sponsored ads. 100% ship with Prime. On an average day, 0.0% of listings are out of stock. The average listing ranks #88 within Allergy, Sinus & Asthma. It carries 15,030 reviews at 4.73 stars, so a new listing needs social proof before a better product.
- Sponsored listings
- 80%
- Prime listings
- 100%
- Out of stock, average day
- 0.0%
- Average rank
- #88in Allergy, Sinus & Asthma
- Average rating
- 4.73 starsAmazon United States average 4.42 stars
- Average reviews
- 15,030per listing
- Listings tracked
- 15
04 · Newcomers
1 of last year's 2 launches cleared the first-year sales bar.
2 products launched here in the last 12 months. 1 of them cleared the first-year sales bar, our mark for a successful launch. The brands on the shelf have sold for 78 months on average, so the names here are established.
- Launched, last 12 months
- 2
- Successful launches
- 1Amazon's first-year sales bar
- Average brand age
- 78 months
Products
Top Diphenhydramine products & what they sell for
The products selling here, as shoppers see them on Amazon. Shelf share and sales are our estimates.
Prices and ratings read from Amazon on Jul 11, 2026. The live listing can differ.
Top sellers
by estimated 90-day click share
Amazon Basic Care Allergy Relief Diphenhydramine HCl 25 mg Antihistamine Tablets for Symptoms Due to Hay Fever and Upper Respiratory Allergies Mini-Tabs 100 Count
- Price
- $4.12
- Rating
- 4.8/5
- Reviews
- 54,786
- Age
- 7y ago

Amazon Basic Care Complete Allergy Relief Diphenhydramine HCl 25 mg Easy to Swallow Mini-Tabs Relieves Sneezing Itchy Eyes Runny Nose Itchy Throat 400 Count
- Price
- $8.12
- Rating
- 4.8/5
- Reviews
- 54,786
- Age
- 8y ago

HEALTH LFE Allergy Relief Medicine Diphenhydramine HCl Caplets 25 mg | Children and Adults | Relieves Sneezing Runny Nose Hay Fever Symptoms Itchy Eyes and Throat (Large 1000 Count)
- Price
- $10.12
- Rating
- 4.8/5
- Reviews
- 2,715
- Age
- 5y ago

MedPlus Allergy Relief Medicine Diphenhydramine HCl 25 mg 1000 Tablets Antihistamine Relief for Indoor & Outdoor Allergies Made in USA
- Price
- $10.33
- Rating
- 4.8/5
- Reviews
- 1,330
- Age
- 3y ago

TIME-Cap Labs 650 Caplets Diphenhydramine HCl 25mg Allergy Relief Antihistamine for Adults Helps Relieve Sneezing Runny Nose Itchy Watery Eyes & Itchy Throat
- Price
- $8.77
- Rating
- 4.8/5
- Reviews
- 5,236
- Age
- 4y ago
Trending
estimated 90-day click momentum
Safrel Allergy Relief Medication 25mg Diphenhydramine HCl Antihistamine for Sneezing Runny Nose Itchy Eyes and Throat Indoor and Outdoor Allergies (1000 Count)
- Price
- $10.11
- Rating
- 4.7/5
- Reviews
- 4,789
- Age
- 5y ago

GoodMeds Allergy Medicine Antihistamine Diphenhydramine HCl 25 mg | Children and Adults | Relieve Itchy Eyes Runny Nose Sneezing (25 mg 600 Tablets)
- Price
- $9.60
- Rating
- 4.8/5
- Reviews
- 534
- Age
- 6mo ago

Berkley Jensen Allergy Relief Tablets 25mg Diphenhydramine HCI 600 Count
- Price
- $8.00
- Rating
- 4.6/5
- Reviews
- 189
- Age
- 5mo ago

HEALTH LFE HealthLife Sleep Aid (Diphenhydramine HCl Caplets 25 mg Blue) 300 Count
- Price
- $7.03
- Rating
- 4.6/5
- Reviews
- 483
- Age
- 3y ago

MedPlus Allergy Relief Medicine Diphenhydramine HCl 25 mg 1000 Tablets Antihistamine Relief for Indoor & Outdoor Allergies Made in USA
- Price
- $10.33
- Rating
- 4.8/5
- Reviews
- 1,330
- Age
- 3y ago
Newest
by launch date
Berkley Jensen Allergy Relief Tablets 25mg Diphenhydramine HCI 600 Count
- Price
- $8.00
- Rating
- 4.6/5
- Reviews
- 189
- Age
- 5mo ago

GoodMeds Allergy Medicine Antihistamine Diphenhydramine HCl 25 mg | Children and Adults | Relieve Itchy Eyes Runny Nose Sneezing (25 mg 600 Tablets)
- Price
- $9.60
- Rating
- 4.8/5
- Reviews
- 534
- Age
- 6mo ago

HEALTH LFE HealthLife Sleep Aid (Diphenhydramine HCl Caplets 25 mg Blue) 300 Count
- Price
- $7.03
- Rating
- 4.6/5
- Reviews
- 483
- Age
- 3y ago

MedPlus Allergy Relief Medicine Diphenhydramine HCl 25 mg 1000 Tablets Antihistamine Relief for Indoor & Outdoor Allergies Made in USA
- Price
- $10.33
- Rating
- 4.8/5
- Reviews
- 1,330
- Age
- 3y ago

HealthA2Z Allergy Relief | Diphenhydramine HCL 25mg | Antihistamine | Relief from Itchy Throat Sneezing Runny Noses | Indoor & Outdoors Allergies (200 Caplets (Pack of 1))
- Price
- $5.45
- Rating
- 4.8/5
- Reviews
- 2,441
- Age
- 4y ago
Competition
Competition: brands, sellers & click share
The top 5 products take an estimated 71% of clicks. A locked shelf that new listings rarely crack.
Brands
11 rising
Sellers
60
Est. top-5 brand share
84%
Top 20: 100%
Est. top-5 click share
71%
Top 20: 100%
Open market
11%
- Amazon Basic Care51%
- HEALTH LFE11%
- HealthA2Z10%
- Generic7%
- TIME-CAP LABS, INC.5%
- ValuMeds4%
- Open — no brand owns it (5 brands, 11%)
Demand
Diphenhydramine search demand
Weekly searches over the year, seasonality beneath. Pick a range.
No pronounced peak months · busiest ÷ quietest = 1.3×
Search terms
Top Diphenhydramine search terms shoppers use
The exact words shoppers type, with estimated yearly volume, growth, and conversion.
- diphenhydramine249K/yr
- diphenhydramine 25mg113K/yr
- generic benadryl27K/yr
- amazon basic care34K/yr
- amazon health30K/yr
- diphenhydramine hcl13K/yr
- diphenhydramine hcl 25 mg8K/yr
- benadryl generic7K/yr
- amazon basics medicine10K/yr
- difenhidramina8K/yr
Reviews and returns
What reviews say buyers love and hate about Diphenhydramine
We read the reviews and the return reasons for every product selling here.
“Did not help me sleep”
Every topic
Every topic buyers talk about, one row each.
Red shows the share of negative reviews and green the share of positive reviews, biggest topic first. Open a row to read what they wrote.
16 topics
Keep looking
Related niches
Niches in the same category that score near this one. Research these next.
Best Flapen score
The highest-scoring niches we track right now, across every category.
FAQ
Common Diphenhydramine questions
Answered from the same tracked data.
Figures on this page are estimates modeled from public Amazon pages and third-party keyword data. Amazon does not supply them, and no connected seller's data is used. How we handle Amazon data









