Is acetaminophen pm profitable to sell on Amazon United States?

The niche generates $396K/yr across 8 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is -6.9%. Flapen's verdict: Skip it (38/100).

How competitive is the acetaminophen pm niche?

6 brands and 25 sellers compete. The top 5 products take 89% of clicks and top 5 brands hold 97% of demand.

What do buyers complain about in acetaminophen pm?

Top complaints mined from reviews: Functionality-Overall, Sleep Quality, Size-Overall. The return rate is 0.0%.

When does demand for acetaminophen pm peak?

Demand peaks in Mar–Aug–Sep–Nov–Dec; the busiest month runs 7.4× the quietest.

What does it cost to enter the acetaminophen pm niche?

Listings span $5.87–$15.20; the average listing price is $10.91 (sweet spot $15–$100). The average incumbent carries 5,559 reviews — the moat a new listing must climb.

acetaminophen pm

Skip it

Prices mostly outside the sweet spot ($5.87–$15.20) — this niche doesn't clear our bar today.

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Conversion

Incredible18.7%

search→purchase rate — share of searches ending in a sale

Market size

Good$396K

$396K/yr · 194K searches

Avg price

Okay$10.91

avg listing price — sweet spot $15–$100

Review moat

Bad5,558.63

avg incumbent reviews — the moat a new listing must climb

Growth

Bad-6.9%

90-day search growth — must beat 0% to launch

Quality gap

Bad4.8★

avg incumbent rating — lower means beatable quality

Competition

Bad89%

top-5 click share — a locked-up shelf

Brand share

Bad97%

top-5 brand share — brand-locked demand

Price range

Bad$5.87–$15.20

cheapest to priciest tracked listing — scored on the share inside $15–$100

According to Flapen's Amazon United States niche tracking, acetaminophen pm is a $396K/yr Amazon United States market (194K searches/yr). The top 5 brands hold 97% of demand. Demand peaks in Mar–Aug–Sep–Nov–Dec. Verdict: Skip it — 38/100.

Data updated Jul 11, 2026 · scored weekly · How we score niches

acetaminophen pm market data

Units sold / yr: 40K–50K; avg 4,000–5,000/product
Revenue / yr: $436K–$546K; units × avg price
Conversion rate: 18.7%
Avg BSR: #56
Page quality: 0%
Prime: 100%
Sponsored: 100%
Out of stock: 0.0%
Avg brand age: 83 months
Avg seller age: 156 days

Competition & brand share

The top 5 products capture 89% of clicks — a locked-up shelf that new listings rarely crack.

Brands

6 falling

Sellers

Top-5 brand share

97%

Top 20: 100%

Top-5 click share

89%

Top 20: 100%

Open market

Amazon Basic Care37%
HealthA2Z19%
GoodMeds16%
TIME-CAP LABS, INC.13%
RIGHT REMEDIES13%
GenCare3%
Open — no brand owns it (0%)

Demand & seasonality

Weekly Amazon search volume, last 104 weeks — -6.9% search growth over the last 90 days.

Peak months: Mar, Aug, Sep, Nov, Dec · busiest ÷ quietest = 7.4×

Open Trend

Top acetaminophen pm search terms

acetaminophen pm77K/yr -6.9%18.4% conv.
pm pain reliever53K/yr -3.9%17.2% conv.
pain relief pm14K/yr -8.0%17.5% conv.
acetaminophen 500mg extra strength pm8K/yr +27.0%15.8% conv.
acetaminophen pm 500mg extra strength8K/yr -21.2%19.4% conv.
pain reliever pm5K/yr +4.6%15.9% conv.
pm pain reliever nighttime sleep-aid8K/yr -34.3%10.4% conv.
generic tylenol pm5K/yr -8.7%22.9% conv.
pm pills5K/yr -10.5%10.1% conv.
nighttime pain relief with sleep aid3K/yr -24.4%13.4% conv.

All search terms

Top acetaminophen pm products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 8 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Amazon Basic Care Acetaminophen PM Pain Reliever Plus Nighttime Sleep Aid Caplet 100 Count

Amazon Basic Care$5.874.8★11,116 rev

GoodMeds Compare to Tylenol PM Pain Reliever & Sleep Aid Generic Acetaminophen 500mg Fast-Acting Extra Strength for Headaches Migraines Aches | Non-Habit Forming (375 Count)

GoodMeds$12.004.8★261 rev

HealthA2Z Extra Strength Pain Relief PM| Acetaminophen 500mg | Diphenhydramine 25mg | Pain Reliever & Nighttime Sleep Aid | (365 Count (Pack of 1))

HealthA2Z$15.204.7★10,921 rev

TIME-Cap Labs 400 Caplets Extra Strength Acetaminophen 500mg PM & Diphenhydramine HCl 25mg - PM Pain Reliever & Sleep Aid Helps with Occasional Headaches & Minor Aches & Pains

TIME-CAP LABS, INC.$10.064.8★1,460 rev

RIGHT REMEDIES Extra Strength Pain Relief PM & Nighttime Sleep Aid Caplets 300 Count Acetaminophen 500 mg & Diphenhydramine HCl 25 mg Non-Habit Forming Compare to Active Ingredients of Tylenol PM

RIGHT REMEDIES$10.214.8★1,869 rev

Newest

by launch date

GoodMeds Compare to Tylenol PM Pain Reliever & Sleep Aid Generic Acetaminophen 500mg Fast-Acting Extra Strength for Headaches Migraines Aches | Non-Habit Forming (375 Count)

GoodMeds$12.00261 rev

8mo ago

RIGHT REMEDIES Extra Strength Pain Relief PM & Nighttime Sleep Aid Caplets 300 Count Acetaminophen 500 mg & Diphenhydramine HCl 25 mg Non-Habit Forming Compare to Active Ingredients of Tylenol PM

RIGHT REMEDIES$10.211,869 rev

2y ago

TIME-Cap Labs 400 Caplets Extra Strength Acetaminophen 500mg PM & Diphenhydramine HCl 25mg - PM Pain Reliever & Sleep Aid Helps with Occasional Headaches & Minor Aches & Pains

TIME-CAP LABS, INC.$10.061,460 rev

3y ago

Amazon Basic Care Ibuprofen PM Ibuprofen 200 mg and Diphenhydramine Citrate 38 mg Pain Reliever and Nighttime Sleep-Aid Capsule-Shaped Tablets 120 Count

Amazon Basic Care$10.884,368 rev

5y ago

GenCare Extra Strength Acetaminophen PM 500 mg (375 Tablets) | Ultimate Pain Relief & Sleep Support for Adults | Quick Acting & Non Habit Forming Headache Relief | Eases Aches & Joint Discomfort

GenCare$14.823,553 rev

6y ago

What buyers say about acetaminophen pm

What buyers praise and complain about, mined from review topics.

What buyers love

Value For Money31%

“Great deal”

Sleep Quality16%

“help me fall asleep”

Quality-Overall13%

“the quality is consistent”

Advertised Vs Actual Product13%

“As advertised”

Efficiency8%

“Effective”

Ease Of Use2%

“easy to use”

Ingredients-Overall2%

“The ingredients are clearly listed”

Side Effects2%

“Exactly the same effects as name brand T. PM”

Strength2%

“Effective”

Dosage1%

“These work just as good as Tylenol PM however”

What buyers complain about

Functionality-Overall28%

“I could not function”

Sleep Quality21%

“does not help with sleep”

Size-Overall6%

“The pills are rather large”

Taste-Overall5%

“Weird taste”

Pain Relief-Overall5%

“Pain”

Quality-Overall4%

“Cheap”

Value For Money2%

“much cheaper”

Allergies2%

“allergic to Benadryl”

Dosage2%

“since other generic brands don't work with the regular dose”

Advertised Vs Actual Product1%

“reading the bottle show it is not”

Common questions

Is acetaminophen pm profitable to sell on Amazon United States?: The niche generates $396K/yr across 8 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is -6.9%. Flapen's verdict: Skip it (38/100).
How competitive is the acetaminophen pm niche?: 6 brands and 25 sellers compete. The top 5 products take 89% of clicks and top 5 brands hold 97% of demand.
What do buyers complain about in acetaminophen pm?: Top complaints mined from reviews: Functionality-Overall, Sleep Quality, Size-Overall. The return rate is 0.0%.
When does demand for acetaminophen pm peak?: Demand peaks in Mar–Aug–Sep–Nov–Dec; the busiest month runs 7.4× the quietest.
What does it cost to enter the acetaminophen pm niche?: Listings span $5.87–$15.20; the average listing price is $10.91 (sweet spot $15–$100). The average incumbent carries 5,559 reviews — the moat a new listing must climb.