Is zofran profitable to sell on Amazon United States?

The niche generates $92K/yr across 11 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is +0.1%. Flapen's verdict: Skip it (30/100).

How competitive is the zofran niche?

7 brands and 65 sellers compete. The top 5 products take 83% of clicks and top 5 brands hold 96% of demand.

What do buyers complain about in zofran?

Top complaints mined from reviews: Smell, Taste-Overall, Functionality-Overall. The return rate is 0.0%.

When does demand for zofran peak?

Demand peaks in Jan–Feb; the busiest month runs 2.0× the quietest.

What does it cost to enter the zofran niche?

Listings span $5.57–$15.38; the average listing price is $9.36 (sweet spot $15–$100). The average incumbent carries 3,804 reviews — the moat a new listing must climb.

zofran

Skip it

Prices mostly outside the sweet spot ($5.57–$15.38) — this niche doesn't clear our bar today.

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Conversion

Okay3.7%

search→purchase rate — share of searches ending in a sale

Avg price

Okay$9.36

avg listing price — sweet spot $15–$100

Quality gap

Okay4.6★

avg incumbent rating — lower means beatable quality

Review moat

Okay3,803.64

avg incumbent reviews — the moat a new listing must climb

Growth

Okay+0.1%

90-day search growth — must beat 0% to launch

Market size

Bad$92K

$92K/yr · 266K searches

Competition

Bad83%

top-5 click share — a locked-up shelf

Brand share

Bad96%

top-5 brand share — brand-locked demand

Price range

Bad$5.57–$15.38

cheapest to priciest tracked listing — scored on the share inside $15–$100

According to Flapen's Amazon United States niche tracking, zofran is a $92K/yr Amazon United States market (266K searches/yr). The top 5 brands hold 96% of demand. Demand peaks in Jan–Feb. Verdict: Skip it — 30/100.

Data updated Jul 11, 2026 · scored weekly · How we score niches

zofran market data

Units sold / yr: 10K–13K; avg 1,250–1,500/product
Revenue / yr: $94K–$117K; units × avg price
Conversion rate: 3.7%
Avg BSR: #97
Page quality: 0%
Prime: 100%
Sponsored: 91%
Out of stock: 0.0%
Avg brand age: 105 months
Avg seller age: 164 days

Competition & brand share

The top 5 products capture 83% of clicks — a locked-up shelf that new listings rarely crack.

Brands

7 rising

Sellers

Top-5 brand share

96%

Top 20: 100%

Top-5 click share

83%

Top 20: 100%

Open market

Boiron38%
Nauzene37%
Dramamine13%
Emetrol5%
RUGBY LABORATORIES3%
Allclair2%
Open — no brand owns it (1 brand, 2%)

Demand & seasonality

Weekly Amazon search volume, last 104 weeks — +0.1% search growth over the last 90 days.

Peak months: Jan, Feb · busiest ÷ quietest = 2.0×

Open Trend

Top zofran search terms

zofran180K/yr +5.3%3.2% conv.
zofran anti nausea medicine65K/yr -10.9%5.1% conv.
ondansetron anti nausea medicine9K/yr -2.1%3.7% conv.
zofran dissolving tablets9K/yr -19.8%5.0% conv.
zofran anti nausea3K/yr -31.5%1.3% conv.

All search terms

Top zofran products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 11 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Nauzene Non-drowsy Upset Stomach & Nausea Relief Chewable Tablets - Fast-Acting Relief in 4 Minutes - Doctor Recommended - Wild Cherry Flavor 42 ct

Nauzene$5.574.5★5,913 rev

Boiron NauseaCalm Relief for Upset Stomach Nausea and Vomiting Due to Stomach Flu Overindulgence or Motion Sickness - Non-Drowsy - 60 Count

Boiron$10.634.5★2,529 rev

Dramamine Nausea Relief Tablets Long-Lasting Anti-Nausea Support with 25mg Meclizine HCI 10 Count Pack of 2

Dramamine$9.704.6★4,008 rev

Emetrol Non-Drowsy Nausea Relief - Chewable Medicine for Upset Stomach - Pharmacist Recommended Nausea Relief - Mixed Berry Flavor 60 Tablets

Emetrol$9.854.5★922 rev

Boiron Nux Vomica 30C Homeopathic Medicine for Hangover Relief Upset Stomach Nausea and Overindulgence of Food or Drink - 3 Count (240 Pellets)

Boiron$15.384.7★2,249 rev

Newest

by launch date

Bonine Non-Drowsy Motion Sickness Relief Meclizine - Cruise Ship Essentials

Bonine$6.5212,668 rev

7mo ago

Dramamine Nausea Relief with Meclizine HCl for Long-Lasting Relief of Nausea Vomiting & Dizziness 20 Tablets

Dramamine$9.674,008 rev

2y ago

Allclair Nausea Relief Inhaler for Motion & Morning Sickness Fast-Acting Non-Drowsy Natural Alternative to Pills & Patches Travel Essential (2 Inhalers)

Allclair$12.494,777 rev

2y ago

Emetrol Non-Drowsy Nausea Relief - Chewable Medicine for Upset Stomach - Pharmacist Recommended Nausea Relief - Mixed Berry Flavor 60 Tablets

Emetrol$9.85922 rev

3y ago

Boiron NauseaCalm Relief for Upset Stomach Nausea and Vomiting Due to Stomach Flu Overindulgence or Motion Sickness - Non-Drowsy - 60 Count

Boiron$10.632,529 rev

4y ago

What buyers say about zofran

What buyers praise and complain about, mined from review topics.

What buyers love

Efficiency18%

“Works well”

Smell8%

“Strong scent works well”

Acid Regulator/Stomach Ache Relief6%

“Works great even helps ease an already stomach”

Sinus Relief6%

“Also helps with sinuses”

Value For Money6%

“Great value for the money”

Quality-Overall6%

“The product quality exceeded expectations — well-made”

Advertised Vs Actual Product5%

“Works as advertised”

Taste-Overall4%

“taste fine”

Ease Of Use4%

“Very handy”

Side Effects3%

“No more nausea”

What buyers complain about

Smell13%

“The odor is extremely strong”

Taste-Overall12%

“Doesnt taste good”

Functionality-Overall11%

“it never worked”

Side Effects5%

“I was feeling pretty nauseous one day”

Sinus Relief4%

“Burned my sinus”

Sleep Quality4%

“Does not make me sleepy”

Acid Regulator/Stomach Ache Relief4%

“I have several stomach issues”

Allergies3%

“It appears I have an allergy to something in these”

Pain Relief-Overall3%

“Horrible and painful”

Advertised Vs Actual Product2%

“Doesn't do what it says its supposed to”

Top return reasons

Value For Money100%

Common questions

Is zofran profitable to sell on Amazon United States?: The niche generates $92K/yr across 11 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is +0.1%. Flapen's verdict: Skip it (30/100).
How competitive is the zofran niche?: 7 brands and 65 sellers compete. The top 5 products take 83% of clicks and top 5 brands hold 96% of demand.
What do buyers complain about in zofran?: Top complaints mined from reviews: Smell, Taste-Overall, Functionality-Overall. The return rate is 0.0%.
When does demand for zofran peak?: Demand peaks in Jan–Feb; the busiest month runs 2.0× the quietest.
What does it cost to enter the zofran niche?: Listings span $5.57–$15.38; the average listing price is $9.36 (sweet spot $15–$100). The average incumbent carries 3,804 reviews — the moat a new listing must climb.