Is tributyrin profitable to sell on Amazon United States?

The niche generates $415K/yr across 17 tracked products. 2 of 5 products launched in the last 360 days are still selling. 90-day search growth is +25.7%. Flapen's verdict: Worth a look (65/100).

How competitive is the tributyrin niche?

15 brands and 26 sellers compete. The top 5 products take 67% of clicks and top 5 brands hold 73% of demand.

What do buyers complain about in tributyrin?

Top complaints mined from reviews: Regulates Digestion, Smell, Dosage. The return rate is 0.0%.

When does demand for tributyrin peak?

Demand peaks in May–Jun–Jul; the busiest month runs 1.9× the quietest.

What does it cost to enter the tributyrin niche?

Listings span $14.58–$80.24; the average listing price is $31.73 (sweet spot $15–$100). The average incumbent carries 201 reviews — the moat a new listing must climb.

tributyrin

Worth a look

Shows low returns (0.0%), but a failed launch gate (market size, growth, or returns) keeps it on the watch list.

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Avg price

Incredible$31.73

avg listing price — sweet spot $15–$100

Price range

Great$14.58–$80.24

cheapest to priciest tracked listing — scored on the share inside $15–$100

Review moat

Great200.65

avg incumbent reviews — the moat a new listing must climb

Conversion

Great9.2%

search→purchase rate — share of searches ending in a sale

Quality gap

Good4.4★

avg incumbent rating — lower means beatable quality

Market size

Good$415K

$415K/yr · 143K searches

Growth

Good+25.7%

90-day search growth — must beat 0% to launch

Brand share

Good73%

top-5 brand share — brands hold most of the demand

Competition

Okay67%

top-5 click share — leaders hold, buyers still browse

Signals Low Review Barrier

According to Flapen's Amazon United States niche tracking, tributyrin is a $415K/yr Amazon United States market (143K searches/yr). The top 5 brands hold 73% of demand. Demand peaks in May–Jun–Jul. Verdict: Worth a look — 65/100.

Data updated Jul 25, 2026 · scored weekly · How we score niches

tributyrin market data

Units sold / yr: 10K–13K; avg 500–750/product
Revenue / yr: $317K–$397K; units × avg price
Conversion rate: 9.2%
Avg BSR: #3,160
Page quality: 0%
Prime: 100%
Sponsored: 82%
Out of stock: 0.0%
Avg brand age: 78 months
Avg seller age: 150 days

Competition & brand share

The top 5 products take 67% of clicks — established leaders, but buyers still shop beyond them.

Brands

15 falling

Sellers

Top-5 brand share

73%

Top 20: 100%

Top-5 click share

67%

Top 20: 100%

Open market

22%

Peak Performance23%
Designs for Health21%
Quorinthiumax11%
Healthy Gut11%
ForestVibe7%
Doctor's BEST5%

Demand & seasonality

Weekly Amazon search volume, last 102 weeks — +25.7% search growth over the last 90 days.

Peak months: May, Jun, Jul · busiest ÷ quietest = 1.9×

Open Trend

Top tributyrin search terms

tributyrin76K/yr +39.2%6.2% conv.
tributyrin supplement25K/yr +9.4%7.1% conv.
corebiome tributyrin7K/yr +35.5%7.0% conv.
tributyrate6K/yr +11.3%5.5% conv.
corebiome7K/yr -5.1%3.6% conv.
tributyrin-x7K/yr +18.5%8.7% conv.
tri butyrin supreme3K/yr +57.4%22.8% conv.
tributyrate for constipation3K/yr -38.8%5.8% conv.
butyrin3K/yr +97.6%0.8% conv.
tri-butyrin supreme3K/yr +24.5%23.6% conv.

All search terms

Top tributyrin products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 17 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

CoreBiome Tributyrin Postbiotic Supplement Clinically Tested for Gut Health. More Effective Than Sodium Butyrate Capsules. High Bioavailability Post Biotics for Digestive Leaky Gut Colon Microbiome

Peak Performance$35.164.4★308 rev

Designs for Health Tri-Butyrin Supreme - 3-in-1 Butyric Acid (Butyrate) Postbiotics for Gut Health & Gut Permeability Support - Tributyrin Supplement with Odor-Minimizing Innovation (60 Softgels)

Designs for Health$51.714.6★439 rev

Tributyrin Supplement for Gut & Immune 800mg | High Bioavailability with Microencapsulated Probiotics & Prebiotics - Advanced Liquid-Filled Tributyrin Complex Gluten Free 90 Capsules

Quorinthiumax$27.224.3★377 rev

Healthy Gut Tributyrin-X | Most Bioavailable Butyrate Supplement for Gut Health & Leaky Gut Support | 99% Pure w/Zero Odor | 90 Softgels

Healthy Gut$80.244.4★248 rev

Tributyrin Supplement 550mg Advanced Butyrate Form for Gut Health 60% Standardized More Effective Delivery Than Sodium Butyrate 90 Capsules Non-GMO & Gluten Free Postbiotic Supplement

ForestVibe$21.864.6★54 rev

Newest

by launch date

Sports Research Tribiotic 3-in-1 Pre Post & Probiotic 30 Liquid Caps

Sports Research$33.5527 rev

3mo ago

VitalOne$18.1624 rev

5mo ago

YOUBYNATURE$16.4924 rev

5mo ago

Tributyrin Supplement 550mg Advanced Butyrate Form for Gut Health 60% Standardized More Effective Delivery Than Sodium Butyrate 90 Capsules Non-GMO & Gluten Free Postbiotic Supplement

ForestVibe$21.8654 rev

7mo ago

Immortal Herbs Tributyrin Supplement 800mg Advanced Butyrate Form 55% Standardized More Effective Delivery Than Sodium Butyrate 120 Capsules Non-GMO & Gluten Free Postbiotic Supplement

Immortal Herbs$23.9251 rev

7mo ago

What buyers say about tributyrin

What buyers praise and complain about, mined from review topics.

What buyers love

Regulates Digestion18%

“Great digestive enhancer”

Nutritional Content8%

“this supplement was recommended”

Quality-Overall7%

“Great Product, Works as advertised”

Ease Of Chewing/Swallowing7%

“so I did not have any issues with swallowing them”

Value For Money5%

“a good value”

Efficiency5%

“I think it's effective for me”

Acid Regulator/Stomach Ache Relief4%

“This has helped my stomach a lot”

Ingredients-Overall4%

“Good ingredients”

Vitamin4%

“Great for adding to daily supplement intake”

Ease Of Use4%

“it's easy to use”

What buyers complain about

Regulates Digestion6%

“Causes digestive issues”

Smell6%

“off smell to it”

Dosage5%

“certainly not 800mg”

Advertised Vs Actual Product5%

“the mismatch between the listing”

Taste-Overall4%

“the pill is tasteless”

Side Effects3%

“broke out in hives”

Ingredients-Overall3%

“Any ingredients in this product is so small it could never have a change in any body function”

Functionality-Overall2%

“Does not work”

Size-Overall2%

“The capsules are somewhat large”

Weight Loss2%

“It did not help me lose weight”

Top return reasons

Smell50%

Color50%

Common questions

Is tributyrin profitable to sell on Amazon United States?: The niche generates $415K/yr across 17 tracked products. 2 of 5 products launched in the last 360 days are still selling. 90-day search growth is +25.7%. Flapen's verdict: Worth a look (65/100).
How competitive is the tributyrin niche?: 15 brands and 26 sellers compete. The top 5 products take 67% of clicks and top 5 brands hold 73% of demand.
What do buyers complain about in tributyrin?: Top complaints mined from reviews: Regulates Digestion, Smell, Dosage. The return rate is 0.0%.
When does demand for tributyrin peak?: Demand peaks in May–Jun–Jul; the busiest month runs 1.9× the quietest.
What does it cost to enter the tributyrin niche?: Listings span $14.58–$80.24; the average listing price is $31.73 (sweet spot $15–$100). The average incumbent carries 201 reviews — the moat a new listing must climb.