Is reverse periodontal disease profitable to sell on Amazon United States?

The niche generates $129K/yr across 18 tracked products. 0 of 2 products launched in the last 360 days are still selling. 90-day search growth is -16.7%. Flapen's verdict: Skip it (47/100).

How competitive is the reverse periodontal disease niche?

8 brands and 64 sellers compete. The top 5 products take 69% of clicks and top 5 brands hold 94% of demand.

What do buyers complain about in reverse periodontal disease?

Top complaints mined from reviews: Value For Money, Functionality-Overall, Stain Resistance. The return rate is 0.2%.

What does it cost to enter the reverse periodontal disease niche?

Listings span $6.79–$45.29; the average listing price is $22.83 (sweet spot $15–$100). The average incumbent carries 4,500 reviews — the moat a new listing must climb.

reverse periodontal disease

Skip it

Brand-locked demand (top 5 brands take 94% of clicks) — this niche doesn't clear our bar today.

Returns

Incredible0.2%

return rate — above 5% kills the launch gate

Avg price

Incredible$22.83

avg listing price — sweet spot $15–$100

Conversion

Great8.0%

search→purchase rate — share of searches ending in a sale

Price range

Great$6.79–$45.29

cheapest to priciest tracked listing — scored on the share inside $15–$100

Quality gap

Good4.4★

avg incumbent rating — lower means beatable quality

Market size

Okay$129K

$129K/yr · 71K searches

Competition

Okay69%

top-5 click share — leaders hold, buyers still browse

Review moat

Bad4,499.78

avg incumbent reviews — the moat a new listing must climb

Growth

Bad-16.7%

90-day search growth — must beat 0% to launch

Brand share

Bad94%

top-5 brand share — brand-locked demand

According to Flapen's Amazon United States niche tracking, reverse periodontal disease is a $129K/yr Amazon United States market (71K searches/yr). The top 5 brands hold 94% of demand. Verdict: Skip it — 47/100.

Data updated Jul 14, 2026 · scored weekly · How we score niches

reverse periodontal disease market data

Units sold / yr: 5K–6K; avg 250–500/product
Revenue / yr: $114K–$137K; units × avg price
Conversion rate: 8.0%
Avg BSR: #342
Page quality: 0%
Prime: 100%
Sponsored: 72%
Out of stock: 0.0%
Avg brand age: 60 months
Avg seller age: 151 days

Competition & brand share

The top 5 products take 69% of clicks — established leaders, but buyers still shop beyond them.

Brands

8 falling

Sellers

Top-5 brand share

94%

Top 20: 100%

Top-5 click share

69%

Top 20: 100%

Open market

CAREDO81%
The Goodbye Company5%
Gengigel3%
OraMD3%
Orajel2%
Anbesol2%
Open — no brand owns it (2 brands, 4%)

Demand

Weekly Amazon search volume, last 41 weeks — -16.7% search growth over the last 90 days.

Open Trend

Top reverse periodontal disease search terms

caredo toothpaste18K/yr +0.5%11.0% conv.
caredo9K/yr -0.3%9.1% conv.
gum inflammation relief12K/yr -37.0%3.8% conv.
deep gum pocket treatment8K/yr -29.7%1.6% conv.
gum medicine for adults4K/yr -17.2%8.2% conv.
arestin antibiotic for gums4K/yr -20.3%1.3% conv.
caredo reverse cavity toothpaste4K/yr -26.9%13.4% conv.
reverse periodontal disease5K/yr +38.1%1.6% conv.
heal swollen gums6K/yr -47.7%3.5% conv.
antibiotics for swollen gums2K/yr -28.6%1.0% conv.

All search terms

Top reverse periodontal disease products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 18 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

CAREDO Gum Toothpaste for Periodontitis Gum Repair for Receding Gums Gum Disease & Gingivitis Treatment Periodontal Disease Treatment for Gum Health Gum Disease Repair Bad Breath Toothpaste 3.52OZ

CAREDO$25.454.3★1,893 rev

CAREDO Cavity Reversal Hydroxyapatite Toothpaste for Adults Cavity Tooth Filler as Home Cavity Repair Fluoride Free Reverse Cavities Treatment for Tooth Decay Repair Remineralizing Repair 3.52OZ

CAREDO$26.614.2★1,515 rev

Toothpaste Gum Repair for Avoid Root Canal Therapy Gingivitis Treatment for Pulpitis Discomforts and Tooth Repair Remineralizing Hydroxyapatite Toothpaste for Root Canal Discomforts Mint 3.52 OZ

CAREDO$28.424.2★218 rev

The Goodbye Company Gum Disease Treatment - 100% Pure Neem & Clove Oil - Natural Gingivitis Remedy - Non-Toxic BPA-Free Oral Care - Fast-Acting Gum Healer (30ml)

The Goodbye Company$19.054.1★4,696 rev

CAREDO Cavity Repair Toothpaste Cure Tooth Cavities Dental Caries Remineralizing with Hydroxyapatite Toothpaste Treatment Tooth Decay for Adults Home School or Travel (New Flavor 100g*1) Grey White

CAREDO$25.624.4★200 rev

Newest

by launch date

CAREDO Oral Soothing Cream for Tooth & Gum Discomfort Helps Calm Gum Swelling Mouth Irritation & Canker Sores Hydroxyapatite Oral Care Gel for Post-Dental Comfort Implants & Braces 0.56 oz

CAREDO$18.7714 rev

5mo ago

CAREDO Triple Whitening Toothpaste for Sensitive Teeth Gentle Fluoride-Free Nano-Hydroxyapatite & Advanced Enzyme Deep Clean Stain Removal Lasting Brightness Remineralizing Toothpaste Minty 3.52OZ

CAREDO$25.5320 rev

9mo ago

CAREDO New Taste Gum Repair Toothpaste for Adults Fluoride Free Periodontal Treatment for Receding Gums Recession Bleeding Periodontitis Reverse Gingivitis Plaque Control & Bad Breath 3.52 OZ

CAREDO$25.4115 rev

1y ago

CAREDO Cavity Repair Toothpaste Cure Tooth Cavities Dental Caries Remineralizing with Hydroxyapatite Toothpaste Treatment Tooth Decay for Adults Home School or Travel (New Flavor 100g*1) Grey White

CAREDO$25.62200 rev

2y ago

Toothpaste Gum Repair for Avoid Root Canal Therapy Gingivitis Treatment for Pulpitis Discomforts and Tooth Repair Remineralizing Hydroxyapatite Toothpaste for Root Canal Discomforts Mint 3.52 OZ

CAREDO$28.42218 rev

2y ago

What buyers say about reverse periodontal disease

What buyers praise and complain about, mined from review topics.

What buyers love

Quality-Overall17%

“Excellent Product”

Tooth Sensitivity15%

“Helps with my gum”

Efficiency13%

“Works well when needed”

Value For Money9%

“Worth the price”

Advertised Vs Actual Product6%

“As advertised”

Breathability5%

“No more bad breath”

Cleansing4%

“your mouth feeling clean”

Tooth Brightening4%

“It definitely helped my gums”

Ease Of Use3%

“Easy to use”

Oral Hygiene3%

“Great till you see dentist”

What buyers complain about

Value For Money17%

“Waste of money”

Functionality-Overall8%

“Still didnt help”

Stain Resistance5%

“stains badly”

Allergies4%

“Allergic reaction”

Pain Relief-Overall4%

“I dont feel like it did much to help with the pain”

Size-Overall4%

“that is probably due to maybe they don't fit right”

Oral Hygiene3%

“Severly burns for days the inside of my mouth”

Advertised Vs Actual Product3%

“It did not do what the ad says”

Taste-Overall3%

“Doesn't taste good”

Quality-Overall3%

“Trash item”

Top return reasons

Advertised Vs Actual Product19%

Leak-Proof14%

Functionality-Overall13%

Value For Money13%

Size-Overall6%

Stain Resistance6%

Smell4%

Defective Material/Parts4%

Ingredients-Overall3%

Breathability3%

Common questions

Is reverse periodontal disease profitable to sell on Amazon United States?: The niche generates $129K/yr across 18 tracked products. 0 of 2 products launched in the last 360 days are still selling. 90-day search growth is -16.7%. Flapen's verdict: Skip it (47/100).
How competitive is the reverse periodontal disease niche?: 8 brands and 64 sellers compete. The top 5 products take 69% of clicks and top 5 brands hold 94% of demand.
What do buyers complain about in reverse periodontal disease?: Top complaints mined from reviews: Value For Money, Functionality-Overall, Stain Resistance. The return rate is 0.2%.
What does it cost to enter the reverse periodontal disease niche?: Listings span $6.79–$45.29; the average listing price is $22.83 (sweet spot $15–$100). The average incumbent carries 4,500 reviews — the moat a new listing must climb.