Is rapid release acetaminophen 500mg profitable to sell on Amazon United States?

The niche generates $1.8M/yr across 13 tracked products. 2 of 2 products launched in the last 360 days are still selling. 90-day search growth is -29.8%. Flapen's verdict: Skip it (44/100).

How competitive is the rapid release acetaminophen 500mg niche?

3 brands and 85 sellers compete. The top 5 products take 78% of clicks and top 5 brands hold 100% of demand.

What do buyers complain about in rapid release acetaminophen 500mg?

Top complaints mined from reviews: Size-Overall, Functionality-Overall, Value For Money. The return rate is 0.0%.

When does demand for rapid release acetaminophen 500mg peak?

Demand is steady year-round — the busiest month runs 1.3× the quietest.

What does it cost to enter the rapid release acetaminophen 500mg niche?

Listings span $4.77–$22.38; the average listing price is $10.81 (sweet spot $15–$100). The average incumbent carries 30,126 reviews — the moat a new listing must climb.

rapid release acetaminophen 500mg

Skip it

Brand-locked demand (top 5 brands take 100% of clicks) — this niche doesn't clear our bar today.

Conversion

Incredible19.3%

search→purchase rate — share of searches ending in a sale

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Market size

Great$1.8M

$1.8M/yr · 845K searches

Price range

Okay$4.77–$22.38

cheapest to priciest tracked listing — scored on the share inside $15–$100

Avg price

Okay$10.81

avg listing price — sweet spot $15–$100

Competition

Bad78%

top-5 click share — a locked-up shelf

Quality gap

Bad4.8★

avg incumbent rating — lower means beatable quality

Review moat

Bad30,126.31

avg incumbent reviews — the moat a new listing must climb

Growth

Bad-29.8%

90-day search growth — must beat 0% to launch

Brand share

Bad100%

top-5 brand share — brand-locked demand

According to Flapen's Amazon United States niche tracking, rapid release acetaminophen 500mg is a $1.8M/yr Amazon United States market (845K searches/yr). The top 5 brands hold 100% of demand. Verdict: Skip it — 44/100.

Data updated Jul 11, 2026 · scored weekly · How we score niches

rapid release acetaminophen 500mg market data

Units sold / yr: 150K–200K; avg 15,000–20,000/product
Revenue / yr: $1.6M–$2.2M; units × avg price
Conversion rate: 19.3%
Avg BSR: #83
Page quality: 0%
Prime: 100%
Sponsored: 77%
Out of stock: 0.0%
Avg brand age: 91 months
Avg seller age: 151 days

Competition & brand share

The top 5 products capture 78% of clicks — a locked-up shelf that new listings rarely crack.

Brands

3 flat

Sellers

Top-5 brand share

100%

Top 20: 100%

Top-5 click share

78%

Top 20: 100%

Open market

Tylenol90%
Amazon Basic Care6%
Boiron4%
Open — no brand owns it (0%)

Demand & seasonality

Weekly Amazon search volume, last 104 weeks — -29.8% search growth over the last 90 days.

No pronounced peak months · busiest ÷ quietest = 1.3×

Open Trend

Top rapid release acetaminophen 500mg search terms

tylenol rapid release extra strength203K/yr -5.0%23.3% conv.
tylenol cold and flu severe164K/yr -47.7%19.0% conv.
tylenol cold and flu141K/yr -60.3%14.3% conv.
tylenol rapid release35K/yr +11.7%16.8% conv.
belladonna 30c34K/yr -15.1%17.6% conv.
tylenol gel caps31K/yr -15.1%15.2% conv.
tylenol cold41K/yr -31.5%13.3% conv.
tylenol liquid gels33K/yr -56.8%13.9% conv.
rapid release tylenol19K/yr +2.0%17.6% conv.
fever reducer20K/yr -14.0%1.8% conv.

All search terms

Top rapid release acetaminophen 500mg products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 13 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Tylenol Rapid Release Extra Strength Gelcaps Acetaminophen 500 mg per Gel Laser Drilled Holes Allow Fast Strong Pain Relief Fever Reducer Gentle on Stomach 100 Count Size

Tylenol$12.034.8★88,762 rev

Tylenol Rapid Release Extra Strength Gelcaps Acetaminophen 500 mg per Gel Laser Drilled Holes Allow Fast Strong Pain Relief Fever Reducer Gentle on Stomach 225 Count Value Size

Tylenol$22.384.8★88,762 rev

Tylenol Cold + Flu Severe Medicine Caplets for Cold & Flu Symptom Relief Fever Reducer Pain Reliever Cough Suppressant Nasal Decongestant & Expectorant with Acetaminophen 24 ct.

Tylenol$7.384.8★7,385 rev

Tylenol Cold + Flu Severe Daytime + Nighttime Cold Medicine Caplets Combo Pack for Multi-Symptom Cough Sore Throat Headache Nasal Congestion Relief Acetaminophen Pain Reliever 24 Count

Tylenol$7.394.8★10,622 rev

Amazon Basic Care Rapid Release Acetaminophen Caplets 500 mg Extra Strength Pain Reliever and Fever Reducer for Headache Backache Menstrual Pain Arthritis Pain 400 Count

Amazon Basic Care$18.634.7★12,181 rev

Newest

by launch date

Tylenol Extra Strength Acetaminophen Liquid Gels 500 mg per Gel Strong Fast Pain Relief Capsules Fever Reducer Gentle on Stomach Relieve Headache Pain Backache and Muscle Aches 75 Count

Tylenol$15.521,291 rev

11mo ago

Tylenol Extra Strength Acetaminophen Liquid Gels 500 mg per Gel Strong Fast Pain Relief Capsules Fever Reducer Gentle on Stomach Relieve Headache Pain Backache and Muscle Aches 40 Count

Tylenol$10.921,291 rev

11mo ago

Tylenol Day & Night Cold & Flu Multi-Symptom Liquid Gels Combo Pack Cold & Flu Relief Medicine Pain Reliever & Fever Reducer + Cough Suppressant & Antihistamine 24 ct

Tylenol$9.32603 rev

1y ago

Tylenol Extra Strength Acetaminophen Rapid Release Gels Fast Strong Pain Relief Fever Reducer 500 mg Gelcaps with LaserDrilled Holes for Fast Release OTC Medicine 50 Count

Tylenol$8.2188,762 rev

5y ago

Amazon Basic Care Rapid Release Acetaminophen Caplets 500 mg Extra Strength Pain Reliever and Fever Reducer for Headache Backache Menstrual Pain Arthritis Pain 400 Count

Amazon Basic Care$18.6312,181 rev

8y ago

What buyers say about rapid release acetaminophen 500mg

What buyers praise and complain about, mined from review topics.

What buyers love

Value For Money18%

“Very affordable”

Efficiency12%

“WORKS WELL”

Quality-Overall12%

“reliable every time Ive needed it”

Ease Of Chewing/Swallowing7%

“Easily swallowed”

Advertised Vs Actual Product6%

“AS ADVERTISED”

Cold Relief5%

“Works great for flu symptoms”

Ease Of Use4%

“Easy to use”

Dosage3%

“effective as the higher dose pills”

Joint Pain3%

“Great for pain after knee surgery”

Fever Relief2%

“Good to relieve a fever”

What buyers complain about

Size-Overall16%

“Very large pill”

Functionality-Overall8%

“Doesn't work”

Value For Money5%

“Pricey”

Color5%

“For anyone worried about the red color”

Pain Relief-Overall5%

“Doesn't Relieve Pain”

Ease Of Chewing/Swallowing5%

“Hard to Swallow”

Dosage4%

“The effectiveness of Amazons brand of rapid release 5O0 mg is questionable”

Allergies3%

“I have allergies”

Acid Regulator/Stomach Ache Relief3%

“Stomach ache”

Taste-Overall3%

“No real taste”

Common questions

Is rapid release acetaminophen 500mg profitable to sell on Amazon United States?: The niche generates $1.8M/yr across 13 tracked products. 2 of 2 products launched in the last 360 days are still selling. 90-day search growth is -29.8%. Flapen's verdict: Skip it (44/100).
How competitive is the rapid release acetaminophen 500mg niche?: 3 brands and 85 sellers compete. The top 5 products take 78% of clicks and top 5 brands hold 100% of demand.
What do buyers complain about in rapid release acetaminophen 500mg?: Top complaints mined from reviews: Size-Overall, Functionality-Overall, Value For Money. The return rate is 0.0%.
When does demand for rapid release acetaminophen 500mg peak?: Demand is steady year-round — the busiest month runs 1.3× the quietest.
What does it cost to enter the rapid release acetaminophen 500mg niche?: Listings span $4.77–$22.38; the average listing price is $10.81 (sweet spot $15–$100). The average incumbent carries 30,126 reviews — the moat a new listing must climb.