Is pyrilamine maleate profitable to sell on Amazon United States?

The niche generates $214K/yr across 9 tracked products. 90-day search growth is +5.6%. Flapen's verdict: Skip it (42/100).

How competitive is the pyrilamine maleate niche?

6 brands and 59 sellers compete. The top 5 products take 90% of clicks and top 5 brands hold 98% of demand.

What do buyers complain about in pyrilamine maleate?

Top complaints mined from reviews: Functionality-Overall, Side Effects, Value For Money. The return rate is 0.1%.

What does it cost to enter the pyrilamine maleate niche?

Listings span $6.31–$45.30; the average listing price is $14.82 (sweet spot $15–$100). The average incumbent carries 8,558 reviews — the moat a new listing must climb.

pyrilamine maleate

Skip it

Brand-locked demand (top 5 brands take 98% of clicks) — this niche doesn't clear our bar today.

Returns

Incredible0.1%

return rate — above 5% kills the launch gate

Conversion

Great8.4%

search→purchase rate — share of searches ending in a sale

Price range

Great$6.31–$45.30

cheapest to priciest tracked listing — scored on the share inside $15–$100

Avg price

Good$14.82

avg listing price — sweet spot $15–$100

Market size

Okay$214K

$214K/yr · 172K searches

Growth

Okay+5.6%

90-day search growth — must beat 0% to launch

Review moat

Bad8,557.56

avg incumbent reviews — the moat a new listing must climb

Quality gap

Bad4.7★

avg incumbent rating — lower means beatable quality

Competition

Bad90%

top-5 click share — a locked-up shelf

Brand share

Bad98%

top-5 brand share — brand-locked demand

According to Flapen's Amazon United States niche tracking, pyrilamine maleate is a $214K/yr Amazon United States market (172K searches/yr). The top 5 brands hold 98% of demand. Verdict: Skip it — 42/100.

Data updated Jul 11, 2026 · scored weekly · How we score niches

pyrilamine maleate market data

Units sold / yr: 15K–20K; avg 3,000–4,000/product
Revenue / yr: $222K–$296K; units × avg price
Conversion rate: 8.4%
Avg BSR: #88
Page quality: 0%
Prime: 100%
Sponsored: 100%
Out of stock: 5.1%
Avg brand age: 61 months
Avg seller age: 148 days

Competition & brand share

The top 5 products capture 90% of clicks — a locked-up shelf that new listings rarely crack.

Brands

6 rising

Sellers

Top-5 brand share

98%

Top 20: 100%

Top-5 click share

90%

Top 20: 100%

Open market

Midol45%
Buscapina39%
IBgard6%
HealthA2Z5%
Pamprin4%
FLAGELI2%

Demand

Weekly Amazon search volume, last 19 weeks — +5.6% search growth over the last 90 days.

Open Trend

Top pyrilamine maleate search terms

buscapina46K/yr +17.3%4.7% conv.
buscopan34K/yr -8.4%1.4% conv.
midol caffeine free27K/yr +37.8%17.1% conv.
buscapina compuesta25K/yr +5.2%3.2% conv.
caffeine free midol5K/yr +12.5%24.4% conv.
buscopan ibs relief7K/yr -12.0%1.1% conv.
buscapina duo para dolor de estmago7K/yr -39.4%2.2% conv.
pyrilamine maleate4K/yr +11.4%1.8% conv.
buscapina fem menstrual3K/yr -12.1%2.9% conv.
dorival3K/yr -10.3%1.1% conv.

All search terms

Top pyrilamine maleate products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 9 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Buscapina Menstrual Cramps Headaches Joint Aches Pain Relief Caplets Acetaminophen 500mg 24 Count Fast-Acting Period Pain & Bloating Relief - Alivio Rpido Clicos

Buscapina$10.364.7★1,354 rev

Midol Complete Caffeine Free Caplets 24ct: Midol Complete Caffeine Free Menstrual Pain Relief Caplets with Acetaminophen Provides Headache Relief and Period Cramps Relief 24 Count

Midol$6.314.8★2,214 rev

Midol Complete Menstrual Pain Relief Caplets 40 Count - Provides Cramp Headache and Bloating Relief

Midol$8.254.8★19,404 rev

HealthA2Z Menstrual Complete Pain Relief Tablets | Relieves Cramps Bloating Fatigue Backache & Headache (90 Counts)

HealthA2Z$7.834.8★900 rev

IBgard Gut Health Supplement Peppermint Oil Capsules for Abdominal Comfort 12 Capsules

IBgard$11.084.5★19,181 rev

Newest

by launch date

HealthA2Z Menstrual Complete Pain Relief Tablets | Relieves Cramps Bloating Fatigue Backache & Headache (90 Counts)

HealthA2Z$7.83900 rev

1y ago

Mens Dress Shoes Comfort Business Casual Premium Leather Oxford Shoes Fashion Dress Sneakers Office Working Driving Walking Derby Shoe Black 12 US

FLAGELI$45.301,139 rev

2y ago

IBgard Gut Health Supplement Peppermint Oil Capsules for Abdominal Comfort 12 Capsules

IBgard$11.0819,181 rev

2y ago

Buscapina Menstrual Cramps Headaches Joint Aches Pain Relief Caplets Acetaminophen 500mg 24 Count Fast-Acting Period Pain & Bloating Relief - Alivio Rpido Clicos

Buscapina$10.361,354 rev

4y ago

Midol Complete Caffeine Free Caplets 24ct: Midol Complete Caffeine Free Menstrual Pain Relief Caplets with Acetaminophen Provides Headache Relief and Period Cramps Relief 24 Count

Midol$6.312,214 rev

5y ago

What buyers say about pyrilamine maleate

What buyers praise and complain about, mined from review topics.

What buyers love

Efficiency14%

“Works well”

Regulates Digestion13%

“But what is so wonderful is that the capsule does not dissolve until it gets to your intestines where it really counts”

Acid Regulator/Stomach Ache Relief13%

“It really does help with stomach issues”

Menstrual Issues8%

“Really good for period cramps”

Quality-Overall6%

“no complaints so far”

Value For Money5%

“affordable”

Muscle Pain Relief5%

“relaxes my muscles through that time of the month”

Caffeine Content5%

“this caffeine free option is great”

Natural Ingredients3%

“I love that its natural”

Advertised Vs Actual Product3%

“Works as advertised”

What buyers complain about

Functionality-Overall18%

“Not effective enough”

Side Effects11%

“It made my stomach bloating worse”

Value For Money10%

“I wish it was more affordable”

Acid Regulator/Stomach Ache Relief7%

“irritates my stomach badly”

Pain Relief-Overall7%

“it does not provide me with any relief”

Dosage6%

“Really stopped my frequent (10 x)”

Regulates Digestion5%

“Not for GERD”

Muscle Pain Relief5%

“Doesnt really seem to help with cramps”

Sleep Quality3%

“dont take at night”

Joint Pain2%

“Works okay, not the best for period pain”

Top return reasons

Functionality-Overall27%

Advertised Vs Actual Product14%

Feet Fit5%

Dosage5%

Size-Overall5%

Ingredients-Overall4%

Ease Of Chewing/Swallowing4%

Joint Pain3%

Certifications3%

Product Condition3%

Common questions

Is pyrilamine maleate profitable to sell on Amazon United States?: The niche generates $214K/yr across 9 tracked products. 90-day search growth is +5.6%. Flapen's verdict: Skip it (42/100).
How competitive is the pyrilamine maleate niche?: 6 brands and 59 sellers compete. The top 5 products take 90% of clicks and top 5 brands hold 98% of demand.
What do buyers complain about in pyrilamine maleate?: Top complaints mined from reviews: Functionality-Overall, Side Effects, Value For Money. The return rate is 0.1%.
What does it cost to enter the pyrilamine maleate niche?: Listings span $6.31–$45.30; the average listing price is $14.82 (sweet spot $15–$100). The average incumbent carries 8,558 reviews — the moat a new listing must climb.