Proteolytic Enzymes
MaybeAn estimated 0.0% of orders come back. But shoppers spend an estimated $82K a year here, so Proteolytic Enzymes is a Maybe.
- Flapen Score
- 51 / 100Top 40% of 14,768 Health & Household niches · +2 vs the category median of 4951
- Market size
- $82K/yr96K searches / yr
- 90-day growth
- +8.9%search demand this quarter
- Competition
- 58%top-5 click share · 17 brands · 32 sellers
Flapen Score
Proteolytic Enzymes against its category
The dotted line is the Health & Household average. Past it, Proteolytic Enzymes is stronger. Inside it, weaker.
Market
The Proteolytic Enzymes market on Amazon at a glance
Shoppers on Amazon United States searched for Proteolytic Enzymes 96K times last year and spent an estimated $82K. The top 5 brands take 64% of clicks. Demand peaks in Apr. Flapen scores it 51 out of 100, a Maybe.
01 · Demand
An estimated 2.8% of those searches ended in a purchase.
Shoppers searched for this 96K times in the last 12 months. That counts every search on Amazon United States for this niche's terms. An estimated 2.8% of those searches ended in a purchase. Searches in the last 90 days moved +8.9% against the 90 days before. Searches, conversion and average price together put the market at an estimated $82K a year.
- Searches, last 12 months
- 96K
- Growth, 90 days vs prior 90
- +8.9%
- Conversion, latest week
- 2.8%
- Market size, estimated
- $82Ka year
- Peak month
- April2.0× the quietest month
- Top search term
- proteolytic enzymes54K searches a year
02 · Price
A sale here is worth $30.61.
Listings sell for $30.61 on average, from $9.96 to $78.36. Amazon reports units sold in ranges. This niche sold 4K to 5K a year. The average listing sells 250 to 500 of them. At $30.61 that is $8K to $15K a year per listing.
- Average price
- $30.61inside the $15 to $100 sweet spot
- Price range
- $9.96–$78.36
- Amazon United States median price
- $24.38across 115,062 niches
- Units sold a year
- 4K–5K
- Units per listing a year
- 250–500
- Revenue per listing a year
- $8K–$15K
- Returns
- 0.0%of orders · Amazon United States median 2.1%
03 · Entry bar
The bar here is ads and reviews.
90% of listings pay for placement with sponsored ads. 100% ship with Prime. On an average day, 0.0% of listings are out of stock. The average listing ranks #459 within Enzymes. It carries 2,793 reviews at 4.48 stars, so a new listing needs social proof before a better product.
- Sponsored listings
- 90%
- Prime listings
- 100%
- Out of stock, average day
- 0.0%
- Average rank
- #459in Enzymes
- Average rating
- 4.48 starsAmazon United States average 4.42 stars
- Average reviews
- 2,793per listing
- Listings tracked
- 21
04 · Newcomers
1 of last year's 3 launches cleared the first-year sales bar.
3 products launched here in the last 12 months. 1 of them cleared the first-year sales bar, our mark for a successful launch. The brands on the shelf have sold for 99 months on average, so the names here are established.
- Launched, last 12 months
- 3
- Successful launches
- 1Amazon's first-year sales bar
- Average brand age
- 99 months
Products
Top Proteolytic Enzymes products & what they sell for
The products selling here, as shoppers see them on Amazon. Shelf share and sales are our estimates.
Prices and ratings read from Amazon on Jul 26, 2026. The live listing can differ.
Top sellers
by estimated 90-day click share
Doctors Best Proteolytic Enzymes Supplement for Men & Women - Supports Protein Digestion Caps for Digestive Wellness Bromelain Protease & Papain Blend Supports Metabolic Health - 90 Veg Capsules
- Price
- $29.00
- Rating
- 4.3/5
- Reviews
- 4,311
- Age
- 16y ago

Wonder Laboratories Proteolytic Enzymes | Bromelain Papain Pancreatin Trypsin 550 mg Total with Standardized Amylase Lipase and Protease 300 Tablets
- Price
- $27.75
- Rating
- 4.6/5
- Reviews
- 787
- Age
- 6y ago

Carlyle Proteolytic Enzymes | 300 Capsules
- Price
- $19.93
- Rating
- 4.5/5
- Reviews
- 186
- Age
- 3y ago

Wonder Laboratories Proteolytic Enzymes | Bromelain Papain Pancreatin Trypsin 550 mg Total with Standardized Amylase Lipase and Protease 100 Tablets
- Price
- $9.96
- Rating
- 4.6/5
- Reviews
- 787
- Age
- 6y ago

Potent Nattokinase 4000 FU Serrapeptase 240000 SPU Lumbrokinase 2000 FU Supplement - Proteolytic Enzymes Capsules for Energy Support Digestion Detox Cognition & Gut Health for Men & Women
- Price
- $29.44
- Rating
- 4.6/5
- Reviews
- 684
- Age
- 2y ago
Trending
estimated 90-day click momentum
Nutricost Proteolytic Enzymes (6 Digestive Enzymes) 90 Capsules
- Price
- $17.06
- Rating
- 5.0/5
- Reviews
- 13
- Age
- 1mo ago

Nature Captured Systemic Proteolytic Enzyme Complex - Naturally Supports Recovery & Joints - 120 Capsules - Vegan - GMP - Additive Free
- Price
- $19.92
- Rating
- 4.2/5
- Reviews
- 24
- Age
- 7mo ago

Balance ONE Biofilm Disruptor Serrapeptase and Nattokinase 60 Capsules
- Price
- $28.89
- Rating
- 4.4/5
- Reviews
- 256
- Age
- 5y ago

Potent Nattokinase 4000 FU Serrapeptase 240000 SPU Lumbrokinase 2000 FU Supplement - Proteolytic Enzymes Capsules for Energy Support Digestion Detox Cognition & Gut Health for Men & Women
- Price
- $29.44
- Rating
- 4.6/5
- Reviews
- 684
- Age
- 2y ago

Clean Nutraceuticals Nattokinase 5000 FU Serrapeptase 120000 SPU Lumbrokinase Enzyme Supplement with Bromelain Papain Papaya Enzymes Rutin Extract Amla Magnesium Vitamin B6 & VIT C Capsules
- Price
- $22.38
- Rating
- 4.5/5
- Reviews
- 1,299
- Age
- 3y ago
Newest
by launch date
Nutricost Proteolytic Enzymes (6 Digestive Enzymes) 90 Capsules
- Price
- $17.06
- Rating
- 5.0/5
- Reviews
- 13
- Age
- 1mo ago

Nature Captured Systemic Proteolytic Enzyme Complex - Naturally Supports Recovery & Joints - 120 Capsules - Vegan - GMP - Additive Free
- Price
- $19.92
- Rating
- 4.2/5
- Reviews
- 24
- Age
- 7mo ago

HEAL-N-SOOTHE Proteolytic Systemic Enzymes Joint Supplement with Bromelain Papain Boswellia Joint Mobility Muscle Flexibility Protein Digestion Circulatory & Immune Health - 60 Count (1 Pack)
- Price
- $33.88
- Rating
- 4.0/5
- Reviews
- 11,093
- Age
- 11mo ago

Potent Nattokinase 4000 FU Serrapeptase 240000 SPU Lumbrokinase 2000 FU Supplement - Proteolytic Enzymes Capsules for Energy Support Digestion Detox Cognition & Gut Health for Men & Women
- Price
- $29.44
- Rating
- 4.6/5
- Reviews
- 684
- Age
- 2y ago

AMVILAB Proteolytic Enzymes 3X with Serrapeptase Trypsin & Chymotrypsin | Reduces Edema & Irritation from Tissue Injury -Supports Body Wellness & Recovery- Digestive Supplement - 90 Capsules
- Price
- $37.13
- Rating
- 4.3/5
- Reviews
- 444
- Age
- 3y ago
Competition
Competition: brands, sellers & click share
The top 5 products take an estimated 58% of clicks. Leaders hold, but buyers still shop past them.
Brands
17 rising
Sellers
32
Est. top-5 brand share
64%
Top 20: 100%
Est. top-5 click share
58%
Top 20: 99%
Open market
31%
- Wonder Laboratories23%
- Doctor's BEST23%
- Carlyle7%
- AMVILAB6%
- Etta Vita6%
- Piping Rock5%
Demand
Proteolytic Enzymes search demand
Weekly searches over the year, seasonality beneath. Pick a range.
Peak months: Apr · busiest ÷ quietest = 2.0×
Search terms
Top Proteolytic Enzymes search terms shoppers use
The exact words shoppers type, with estimated yearly volume, growth, and conversion.
- proteolytic enzymes54K/yr
- fibrin dissolving enzymes7K/yr
- proteolytic enzymes for inflammation11K/yr
- proteolytic enzymes supplements7K/yr
- enzymes inflammation4K/yr
- wobenzym proteolytic enzymes4K/yr
- proteolytic enzymes inflammation pain4K/yr
- enzyme proteolytic4K/yr
- proteolytic3K/yr
Reviews and returns
What reviews say buyers love and hate about Proteolytic Enzymes
We read the reviews and the return reasons for every product selling here.
“Very hard on your stomach made me sick”
Every topic
Every topic buyers talk about, one row each.
Red shows the share of negative reviews and green the share of positive reviews, biggest topic first. Open a row to read what they wrote.
16 topics
Keep looking
Related niches
Niches in the same category that score near this one. Research these next.
Best Flapen score
The highest-scoring niches we track right now, across every category.
FAQ
Common Proteolytic Enzymes questions
Answered from the same tracked data.
Figures on this page are estimates modeled from public Amazon pages and third-party keyword data. Amazon does not supply them, and no connected seller's data is used. How we handle Amazon data









