Is nystatin cream profitable to sell on Amazon United States?

The niche generates $156K/yr across 18 tracked products. 90-day search growth is -0.7%. Flapen's verdict: Skip it (42/100).

How competitive is the nystatin cream niche?

9 brands and 103 sellers compete. The top 5 products take 64% of clicks and top 5 brands hold 89% of demand.

What do buyers complain about in nystatin cream?

Top complaints mined from reviews: Allergies, Functionality-Overall, Smell. The return rate is 0.1%.

When does demand for nystatin cream peak?

Demand is steady year-round — the busiest month runs 1.5× the quietest.

What does it cost to enter the nystatin cream niche?

Listings span $4.63–$128.04; the average listing price is $18.85 (sweet spot $15–$100). The average incumbent carries 10,325 reviews — the moat a new listing must climb.

nystatin cream

Skip it

A deep review moat (10,325 avg reviews) — this niche doesn't clear our bar today.

Returns

Incredible0.1%

return rate — above 5% kills the launch gate

Avg price

Great$18.85

avg listing price — sweet spot $15–$100

Price range

Good$4.63–$128.04

cheapest to priciest tracked listing — scored on the share inside $15–$100

Conversion

Okay3.4%

search→purchase rate — share of searches ending in a sale

Competition

Okay64%

top-5 click share — leaders hold, buyers still browse

Market size

Okay$156K

$156K/yr · 243K searches

Quality gap

Okay4.6★

avg incumbent rating — lower means beatable quality

Brand share

Okay89%

top-5 brand share — brands hold most of the demand

Growth

Bad-0.7%

90-day search growth — must beat 0% to launch

Review moat

Bad10,324.78

avg incumbent reviews — the moat a new listing must climb

According to Flapen's Amazon United States niche tracking, nystatin cream is a $156K/yr Amazon United States market (243K searches/yr). The top 5 brands hold 89% of demand. Verdict: Skip it — 42/100.

Data updated Jul 18, 2026 · scored weekly · How we score niches

nystatin cream market data

Units sold / yr: 10K–13K; avg 250–500/product
Revenue / yr: $189K–$236K; units × avg price
Conversion rate: 3.4%
Avg BSR: #56
Page quality: 0%
Prime: 94%
Sponsored: 89%
Out of stock: 0.0%
Avg brand age: 87 months
Avg seller age: 148 days

Competition & brand share

The top 5 products take 64% of clicks — established leaders, but buyers still shop beyond them.

Brands

9 flat

Sellers

103

Top-5 brand share

89%

Top 20: 100%

Top-5 click share

64%

Top 20: 100%

Open market

McKesson50%
Globe Pharmacy20%
Globe9%
Medline Remedy5%
Calmoseptine5%
MED PRIDE4%
Open — no brand owns it (3 brands, 7%)

Demand & seasonality

Weekly Amazon search volume, last 104 weeks — -0.7% search growth over the last 90 days.

No pronounced peak months · busiest ÷ quietest = 1.5×

Open Trend

Top nystatin cream search terms

nystatin cream113K/yr +4.4%2.6% conv.
mckesson69K/yr -6.0%1.4% conv.
nystatin ointment10K/yr +25.3%2.1% conv.
mckesson medical supplies9K/yr +30.9%0.6% conv.
nistatina en crema22K/yr -46.4%1.2% conv.
mckesson antifungal cream8K/yr -7.8%24.3% conv.
nystatin cream baby6K/yr -5.8%1.5% conv.
mckesson medical supply3K/yr +40.9%0.4% conv.
mckesson antifungal cream 2 percent miconazole nitrate cream3K/yr -25.3%22.4% conv.

All search terms

Top nystatin cream products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 18 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

McKesson Antifungal Cream 2% Miconazole Nitrate - Relieves Itching Burning Cracking from Jock Itch Ringworm and Athlete Foot - 4 oz. 1 Count

McKesson$8.614.5★9,332 rev

Globe Clotrimazole Antifungal Cream 1% USP (1 oz) Anti Fungal Treatment Relieves Itching Burning Cracking and Scaling Associated Athletes Foot Jock Itch Ringworm and More

Globe Pharmacy$5.114.6★16,475 rev

Medline Remedy Clinical Antifungal Cream 4 FL OZ 1 EA

Medline Remedy$13.144.7★493 rev

Calmoseptine Ointment by Calmoseptine for Skin irritations Diaper Rash Heat Rash Insect Bites and as a Moisture Barrier for Conditions Involving Broken Skin or rashes 1 Count

Calmoseptine$9.934.8★19,960 rev

McKesson Washcloth Wipes for Adults Scented (6 Pack 576 Washcloths) Disposable Wash Cloths for Body - No-Rinse Formula with Snap Lid - Good for Incontinence and Elderly - 96 Wipes Per Pack

McKesson$33.264.7★21,517 rev

Newest

by launch date

McKesson Washcloth Wipes for Adults Scented (6 Pack 576 Washcloths) Disposable Wash Cloths for Body - No-Rinse Formula with Snap Lid - Good for Incontinence and Elderly - 96 Wipes Per Pack

McKesson$33.2621,517 rev

1y ago

Medline Remedy Clinical Antifungal Cream 4 FL OZ 1 EA

Medline Remedy$13.14493 rev

1y ago

MED PRIDE 1% Clotrimazole Antifungal Cream 1oz- Fungus Skin Care Treatment with - Jock Itch Body Ointment - Fights Infection Sweat Rash Athletes Foot Ringworm & Relieves Itching Burning

MED PRIDE$4.644,076 rev

2y ago

Globe (4 Pack Miconazole Nitrate 2% Antifungal Cream Cures Athletes Foot Jock Itch Ringworm and More. 1 OZ Tube

Globe$7.083,564 rev

4y ago

McKesson Antifungal Cream 2% Miconazole Nitrate - Relieves Itching Burning Cracking from Jock Itch Ringworm and Athlete Foot - 4 oz. 3 Count

McKesson$21.719,332 rev

7y ago

What buyers say about nystatin cream

What buyers praise and complain about, mined from review topics.

What buyers love

Quality-Overall14%

“Great product and efficient”

Efficiency13%

“Works Well”

Value For Money12%

“Fair price”

Allergies9%

“no irritation at all”

Advertised Vs Actual Product8%

“As advertised”

Itch Relief4%

“Helps with itch”

Smell4%

“Nice fresh scent”

Ease Of Use3%

“Easy to use”

Moist/Dry3%

“highly recommend for dry skin”

Size-Overall2%

“just the right size”

What buyers complain about

Allergies21%

“Diaper rash”

Functionality-Overall11%

“Didn't work”

Smell8%

“Smells like gasoline”

Thickness4%

“this cream is a little thicker and tacky”

Quality-Overall4%

“or they have poor quality control”

Value For Money3%

“So not worth it”

Adhesion/Stickiness3%

“Horrible adhesion”

Size-Overall3%

“Larger than normal”

Sensitivity-Overall2%

“recently it became very sensitive”

Itch Relief2%

“does not relieve itching”

Top return reasons

Size-Overall28%

Smell13%

Advertised Vs Actual Product8%

Leak-Proof5%

Adhesion/Stickiness5%

Value For Money4%

Absorbency3%

Product Condition3%

Functionality-Overall3%

Quality-Overall3%

Common questions

Is nystatin cream profitable to sell on Amazon United States?: The niche generates $156K/yr across 18 tracked products. 90-day search growth is -0.7%. Flapen's verdict: Skip it (42/100).
How competitive is the nystatin cream niche?: 9 brands and 103 sellers compete. The top 5 products take 64% of clicks and top 5 brands hold 89% of demand.
What do buyers complain about in nystatin cream?: Top complaints mined from reviews: Allergies, Functionality-Overall, Smell. The return rate is 0.1%.
When does demand for nystatin cream peak?: Demand is steady year-round — the busiest month runs 1.5× the quietest.
What does it cost to enter the nystatin cream niche?: Listings span $4.63–$128.04; the average listing price is $18.85 (sweet spot $15–$100). The average incumbent carries 10,325 reviews — the moat a new listing must climb.