Is neupril l-methylfolate profitable to sell on Amazon United States?

The niche generates $58K/yr across 8 tracked products. 0 of 2 products launched in the last 360 days are still selling. 90-day search growth is -17.6%. Flapen's verdict: Skip it (39/100).

How competitive is the neupril l-methylfolate niche?

4 brands and 7 sellers compete. The top 5 products take 89% of clicks and top 5 brands hold 100% of demand.

What do buyers complain about in neupril l-methylfolate?

Top complaints mined from reviews: Functionality-Overall, Side Effects, Dosage. The return rate is 0.0%.

When does demand for neupril l-methylfolate peak?

Demand peaks in Sep–Oct; the busiest month runs 2.6× the quietest.

What does it cost to enter the neupril l-methylfolate niche?

Listings span $18.07–$30.66; the average listing price is $21.55 (sweet spot $15–$100). The average incumbent carries 2,816 reviews — the moat a new listing must climb.

Neupril L-methylfolate

Skip it

Brand-locked demand (top 5 brands take 100% of clicks) — this niche doesn't clear our bar today.

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Price range

Incredible$18.07–$30.66

cheapest to priciest tracked listing — scored on the share inside $15–$100

Conversion

Great11.6%

search→purchase rate — share of searches ending in a sale

Avg price

Great$21.55

avg listing price — sweet spot $15–$100

Review moat

Okay2,815.88

avg incumbent reviews — the moat a new listing must climb

Quality gap

Okay4.6★

avg incumbent rating — lower means beatable quality

Growth

Bad-17.6%

90-day search growth — must beat 0% to launch

Market size

Bad$58K

$58K/yr · 23K searches

Competition

Bad89%

top-5 click share — a locked-up shelf

Brand share

Bad100%

top-5 brand share — brand-locked demand

Is neupril l-methylfolate profitable on Amazon?

According to Flapen's Amazon United States niche tracking, neupril l-methylfolate is a $58K/yr Amazon United States market (23K searches/yr). The top 5 brands hold 100% of demand. Demand peaks in Sep–Oct. Verdict: Skip it — 39/100.

Data updated Jul 28, 2026 · scored weekly · How we score niches

neupril l-methylfolate market size & sales

Units sold, revenue, conversion and listing quality across the tracked shelf.

Units sold / yr: 2K–3K; avg 250–500/product
Revenue / yr: $43K–$54K; units × avg price
Conversion rate: 11.6%
Avg BSR: #92
Page quality: 0%
Prime: 88%
Sponsored: 100%
Out of stock: 0.0%
Avg brand age: 57 months
Avg seller age: 177 days

Competition: brands, sellers & click share

The top 5 products capture 89% of clicks — a locked-up shelf that new listings rarely crack.

Brands

4 rising

Sellers

Top-5 brand share

100%

Top 20: 100%

Top-5 click share

89%

Top 20: 100%

Open market

Triquetra Health81%
Neupril10%
Nichalous6%
Carlyle3%

neupril l-methylfolate demand & seasonality

Weekly Amazon search volume, last 56 weeks — -17.6% search growth over the last 90 days.

Peak months: Sep, Oct · busiest ÷ quietest = 2.6×

Open Trend

Top neupril l-methylfolate products & what they sell for

Every tracked product — its share of the shelf, its review moat, and what it sells for.

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 8 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

L Methyl Folate 15mg Plus Methyl B12 Cofactor Organic Berry Flavor High Potency Liquid Sublingual Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms Vitamin B9 & B12 (1oz)

Triquetra Health$21.874.5★5,924 rev

L Methyl Folate 15mg Plus Methyl B12 Cofactor High Potency Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms of Vitamin B9 & B12 (60 Capsules 60 Servings)

Triquetra Health$21.674.6★9,407 rev

Organic Kids L-Methylfolate + Methyl B12 Cofactor - MTHFR Sublingual Form - 5-MTHF Superior Form of Folate - Adjustable Dosing for All Ages - Mood Behavior Cognition - Organic Berry Flavor 1 Fl oz

Triquetra Health$19.204.5★2,493 rev

Organic Methyl Folate 1000 mcg + Methyl B12 Cofactor (300 Servings) Metabolically Active 5-MTHF Form Organic Berry Flavor Liquid Sublingual Form Mood Cognition Methylation Pregnancy (1oz)

Triquetra Health$21.844.6★4,077 rev

Neupril I-Methylfolate Plus Methyl B12 Berry Flavor (1oz)

Neupril$20.115.0★3 rev

Newest

by launch date

Neupril I-Methylfolate Plus Methyl B12 Berry Flavor (1oz)

Neupril$20.113 rev

3w ago

Nichalous L-Methylfolate 15mg L-Methylfolate + Methyl-B12 Improved Focus and Attention Balanced Mood & Overall Wellness Organic Berry Flavor Liquid Sublingual Form 1fl oz

Nichalous$30.665 rev

8mo ago

Organic Kids L-Methylfolate + Methyl B12 Cofactor - MTHFR Sublingual Form - 5-MTHF Superior Form of Folate - Adjustable Dosing for All Ages - Mood Behavior Cognition - Organic Berry Flavor 1 Fl oz

Triquetra Health$19.202,493 rev

1y ago

Organic L Methylfolate 7.5 mg Plus Methyl B12 Cofactor - Metabolically Active 5-MTHF Form Superior Form of Folate - Organic Berry Flavor Liquid Sublingual Form Mood Cognition Methylation (1oz)

Triquetra Health$18.96589 rev

1y ago

Carlyle L Methylfolate Drops 15mg | 2 Fl Oz | with Organic Glycerin

Carlyle$18.0729 rev

3y ago

What reviews say buyers love and hate about neupril l-methylfolate

What buyers praise and complain about, mined from review topics.

What buyers love

Quality-Overall16%

“Quality and ease of use”

Taste-Overall10%

“Doesnt taste bad”

Focus Enhancement9%

“Helps me focus”

Vitamin8%

“Great vitamin option”

Efficiency7%

“Effective”

Energy Level7%

“More energy”

Advertised Vs Actual Product5%

“Just as advertised”

Ease Of Use4%

“Easy to take”

Value For Money3%

“Worth it”

Flavor3%

“Great flavor”

What buyers complain about

Functionality-Overall11%

“Doesn't do anything”

Side Effects9%

“had some strange side effects”

Dosage7%

“Unless you've been specifically instructed by a doctor to take this high of a dosage”

Taste-Overall7%

“It tastes terrible”

Vitamin4%

“my vitamin b levels were low”

Quality-Overall4%

“Its not as good as they make it seem”

Value For Money4%

“A bit expensive”

Sleep Quality4%

“I also couldnt sleep”

Allergies3%

“Allergic”

Flavor2%

“Nasty flavor”

Top return reasons

Dosage24%

Functionality-Overall18%

Value For Money12%

Vitamin12%

Side Effects6%

Advertised Vs Actual Product6%

Product Condition6%

Vegan/Organic6%

Quality-Overall6%

Natural Ingredients3%

Common neupril l-methylfolate questions

Is neupril l-methylfolate profitable to sell on Amazon United States?: The niche generates $58K/yr across 8 tracked products. 0 of 2 products launched in the last 360 days are still selling. 90-day search growth is -17.6%. Flapen's verdict: Skip it (39/100).
How competitive is the neupril l-methylfolate niche?: 4 brands and 7 sellers compete. The top 5 products take 89% of clicks and top 5 brands hold 100% of demand.
What do buyers complain about in neupril l-methylfolate?: Top complaints mined from reviews: Functionality-Overall, Side Effects, Dosage. The return rate is 0.0%.
When does demand for neupril l-methylfolate peak?: Demand peaks in Sep–Oct; the busiest month runs 2.6× the quietest.
What does it cost to enter the neupril l-methylfolate niche?: Listings span $18.07–$30.66; the average listing price is $21.55 (sweet spot $15–$100). The average incumbent carries 2,816 reviews — the moat a new listing must climb.