Mthfr Test
Skip itA concentrated shelf (top 5 take 93% of clicks) — this niche doesn't clear our bar today.
Returns
Incredible0.1%return rate — above 5% kills the launch gate
Quality gap
Good4.3★avg incumbent rating — lower means beatable quality
Avg price
Good$122.74avg listing price — sweet spot $15–$100
Price range
Okay$21.64–$187.61cheapest to priciest tracked listing — scored on the share inside $15–$100
Market size
Okay$151K$151K/yr · 72K searches
Review moat
Bad6,655.71avg incumbent reviews — the moat a new listing must climb
Conversion
Bad1.7%search→purchase rate — share of searches ending in a sale
Growth
Bad-17.2%90-day search growth — must beat 0% to launch
Brand share
Bad97%top-5 brand share — brand-locked demand
Competition
Bad93%top-5 click share — a locked-up shelf
Is mthfr test profitable on Amazon?
According to Flapen's Amazon United States niche tracking, mthfr test is a $151K/yr Amazon United States market (72K searches/yr). The top 5 brands hold 97% of demand. Verdict: Skip it — 35/100.
Data updated Jul 14, 2026 · scored weekly · How we score niches
mthfr test market size & sales
Units sold, revenue, conversion and listing quality across the tracked shelf.- Units sold / yr
- 1K–2K
- avg 0–100/product
- Revenue / yr
- $153K–$184K
- units × avg price
- Conversion rate
- 1.7%
- Avg BSR
- #27
- Page quality
- 0%
- Prime
- 100%
- Sponsored
- 100%
- Out of stock
- 0.0%
- Avg brand age
- 56 months
- Avg seller age
- 158 days
Competition: brands, sellers & click share
The top 5 products capture 93% of clicks — a locked-up shelf that new listings rarely crack.Brands
6 falling
Sellers
9
Top-5 brand share
97%
Top 20: 100%
Top-5 click share
93%
Top 20: 100%
Open market
0%
- empowerDX55%
- MTHFR20%
- PlexusDX13%
- Triquetra Health5%
- Accentrate5%
- 23andMe3%
mthfr test demand & seasonality
Weekly Amazon search volume, last 104 weeks — -17.2% search growth over the last 90 days.No pronounced peak months · busiest ÷ quietest = 1.4×
Top mthfr test search terms shoppers use
The exact queries shoppers type, with yearly volume, growth and conversion.- mthfr testing kit at home11K/yr
- mthfr gene mutation test17K/yr
- mthfr test7K/yr
- mthfr testing kit23K/yr
- mthfr gene test kit5K/yr
- mthfr gene testing kit3K/yr
- mthfr gene test3K/yr
- gene testing kit mthfr3K/yr
Top mthfr test products & what they sell for
Every tracked product — its share of the shelf, its review moat, and what it sells for.Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.
All 7 tracked products in this niche — three views at once, no toggling.
Top sellers
by 90-day click share
empowerDX MTHFR Gene Test Kit Methylation Test Easy At-Home Test Detects Presence of 677 and 1298 MTHFR Gene Variants Ages 2+ Fast Results Within 6 Days
empowerDX$117.634.3★160 rev
MTHFR-Gene Methylation Test Kit. 1-on-1 Live Expert Support by Phone 7 Days A Week MTHFR C677T and MTHFR A1298C Gene Variants for Methylation Analysis. Results in 2-5 Days. Ages 0+
MTHFR$127.074.5★126 rev
Genetic Methylation Test Kit & MTHFR Testing Kit | 300+ DNA Reports Including MTHFR Gene Variants COMT BHMT AHCY and Folate | Custom Supplement & Meal Plan Recommendations with 10 000 Recipes
PlexusDX$177.863.9★83 rev
MTHFR+COMT Methylation Genes Test Kit. 1-on-1 Live Expert Support by Phone 7 Days A Week. Includes C677T A1298C & V158M Variants for Methylation and Wellness Analysis. Results in 2-5 Days. Ages 0+
MTHFR$187.614.4★68 rev
L Methyl Folate 15mg Plus Methyl B12 Cofactor High Potency Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms of Vitamin B9 & B12 (60 Capsules 60 Servings)
Triquetra Health$21.644.6★9,275 rev
Newest
by launch date
MTHFR Gene Test Kit: At-Home DNA Folate Methylation COMT Analysis & Genetic Health Insights Easy Cheek Swab
Accentrate$119.9819 rev
Genetic Methylation Test Kit & MTHFR Testing Kit | 300+ DNA Reports Including MTHFR Gene Variants COMT BHMT AHCY and Folate | Custom Supplement & Meal Plan Recommendations with 10 000 Recipes
PlexusDX$177.8683 rev
MTHFR-Gene Methylation Test Kit. 1-on-1 Live Expert Support by Phone 7 Days A Week MTHFR C677T and MTHFR A1298C Gene Variants for Methylation Analysis. Results in 2-5 Days. Ages 0+
MTHFR$127.07126 rev
empowerDX MTHFR Gene Test Kit Methylation Test Easy At-Home Test Detects Presence of 677 and 1298 MTHFR Gene Variants Ages 2+ Fast Results Within 6 Days
empowerDX$117.63160 rev
L Methyl Folate 15mg Plus Methyl B12 Cofactor High Potency Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms of Vitamin B9 & B12 (60 Capsules 60 Servings)
Triquetra Health$21.649,275 rev
Trending
90-day click momentumMTHFR Gene Test Kit: At-Home DNA Folate Methylation COMT Analysis & Genetic Health Insights Easy Cheek Swab
Accentrate$119.984.0★
L Methyl Folate 15mg Plus Methyl B12 Cofactor High Potency Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms of Vitamin B9 & B12 (60 Capsules 60 Servings)
Triquetra Health$21.644.6★
empowerDX MTHFR Gene Test Kit Methylation Test Easy At-Home Test Detects Presence of 677 and 1298 MTHFR Gene Variants Ages 2+ Fast Results Within 6 Days
empowerDX$117.634.3★
23andMe Health + Ancestry Service: DNA Test Kit FDA-Authorized Reports Genetic Test Health Predispositions Carrier Status Family Tree (Before You Buy See Important Test Info Below)
23andMe$107.414.6★
MTHFR+COMT Methylation Genes Test Kit. 1-on-1 Live Expert Support by Phone 7 Days A Week. Includes C677T A1298C & V158M Variants for Methylation and Wellness Analysis. Results in 2-5 Days. Ages 0+
MTHFR$187.614.4★
What reviews say buyers love and hate about mthfr test
What buyers praise and complain about, mined from review topics.What buyers love
“Very reliable”
“Good B vitamin supplement”
“easy to operate”
“Great deal”
“Just as advertised”
“Helps with energy”
“My focus is better”
“Works well”
“the instructions were easy to follow”
“Good for people with the MTHFR gene mutation”
What buyers complain about
“Not worth the Money”
“No results”
“Unless you've been specifically instructed by a doctor to take this high of a dosage”
“Way too much Vitamin B9 and B12”
“my heart started racing”
“Did not make me feel any better more tired”
“Low quality”
“not really useful results”
“Maybe it makes a difference if you have a poor diet”
“Im not into swallowing glass so in the trash they go”
Top return reasons
Common mthfr test questions
- Is mthfr test profitable to sell on Amazon United States?
- The niche generates $151K/yr across 7 tracked products. 0 of 1 products launched in the last 360 days are still selling. 90-day search growth is -17.2%. Flapen's verdict: Skip it (35/100).
- How competitive is the mthfr test niche?
- 6 brands and 9 sellers compete. The top 5 products take 93% of clicks and top 5 brands hold 97% of demand.
- What do buyers complain about in mthfr test?
- Top complaints mined from reviews: Value For Money, Functionality-Overall, Dosage. The return rate is 0.1%.
- When does demand for mthfr test peak?
- Demand is steady year-round — the busiest month runs 1.4× the quietest.
- What does it cost to enter the mthfr test niche?
- Listings span $21.64–$187.61; the average listing price is $122.74 (sweet spot $15–$100). The average incumbent carries 6,656 reviews — the moat a new listing must climb.