Methyl Cpg
FailShoppers spend an estimated $34K a year here, so Methyl Cpg is a Fail.
- Flapen Score
- 48 / 100Ranks 7,720 of 14,768 Health & Household niches · −1 vs the category median of 4948
- Market size
- $34K/yr13K searches / yr
- 90-day growth
- +32.1%search demand this quarter
- Competition
- 63%top-5 click share · 13 brands · 37 sellers
Flapen Score
Methyl Cpg against its category
The dotted line is the Health & Household average. Past it, Methyl Cpg is stronger. Inside it, weaker.
Market
The Methyl Cpg market on Amazon at a glance
Shoppers on Amazon United States searched for Methyl Cpg 13K times last year and spent an estimated $34K. The top 5 brands take 70% of clicks. Demand peaks in Jan–Sep–Oct–Nov. Flapen scores it 48 out of 100, a Fail.
01 · Demand
An estimated 5.3% of those searches ended in a purchase.
Shoppers searched for this 13K times in the last 12 months. That counts every search on Amazon United States for this niche's terms. An estimated 5.3% of those searches ended in a purchase. Searches in the last 90 days moved +32.1% against the 90 days before. Searches, conversion and average price together put the market at an estimated $34K a year.
- Searches, last 12 months
- 13K
- Growth, 90 days vs prior 90
- +32.1%
- Conversion, latest week
- 5.3%
- Market size, estimated
- $34Ka year
- Peak month
- November2.4× the quietest month
- Top search term
- methyl cpg10K searches a year
02 · Price
A sale here is worth $48.42.
Listings sell for $48.42 on average, from $12.00 to $202.71. Amazon reports units sold in ranges. This niche sold 500 to 750 a year. The average listing sells 0 to 100 of them. At $48.42 that is $0 to $5K a year per listing.
- Average price
- $48.42inside the $15 to $100 sweet spot
- Price range
- $12.00–$202.71
- Amazon United States median price
- $24.38across 115,062 niches
- Units sold a year
- 500–750
- Units per listing a year
- 0–100
- Revenue per listing a year
- $0–$5K
- Returns
- 0.0%of orders · Amazon United States median 2.1%
03 · Entry bar
The bar here is reviews.
89% of listings pay for placement with sponsored ads. 89% ship with Prime. On an average day, 0.0% of listings are out of stock. The average listing ranks #146 within Vitamin B. It carries 1,960 reviews at 4.72 stars, so a new listing needs social proof before a better product.
- Sponsored listings
- 89%
- Prime listings
- 89%
- Out of stock, average day
- 0.0%
- Average rank
- #146in Vitamin B
- Average rating
- 4.72 starsAmazon United States average 4.42 stars
- Average reviews
- 1,960per listing
- Listings tracked
- 19
04 · Newcomers
Brands here are established.
The brands on the shelf have sold for 95 months on average, so the names here are established.
- Launched, last 12 months
- 0
- Successful launches
- 0Amazon's first-year sales bar
- Average brand age
- 95 months
Products
Top Methyl Cpg products & what they sell for
The products selling here, as shoppers see them on Amazon. Shelf share and sales are our estimates.
Prices and ratings read from Amazon on Jul 28, 2026. The live listing can differ.
Top sellers
by estimated 90-day click share
Ortho Molecular Products Methyl CpG 60 capsules (Pack of 3)
- Price
- $202.71
- Rating
- 4.7/5
- Reviews
- 89
- Age
- 11y ago

THORNE - Methyl-Guard Plus - Active Folate (5-MTHF) with Vitamins B2 B6 & B12 - Supports Methylation & Healthy Level of Homocysteine* - Gluten Dairy & Soy-Free - 30 Servings
- Price
- $60.66
- Rating
- 4.7/5
- Reviews
- 1,776
- Age
- 15y ago

Pure Encapsulations MethylAssist 90s - B Vitamin Complex - Methylation Support* - Heart Health & Brain Health - Non-GMO & Gluten Free - 90 Capsules
- Price
- $61.16
- Rating
- 4.6/5
- Reviews
- 480
- Age
- 12y ago

Methylated B Complex Vitamins Made in USA 2 Month Supply Methyl B Complete Quatrefolic 5-MTHF Folate B12 Methylcobalamin TMG Trimethylglycine Methylfolate Pharm Grade 60 Count
- Price
- $31.14
- Rating
- 4.7/5
- Reviews
- 2,617
- Age
- 12y ago

L Methyl Folate 15mg Plus Methyl B12 Cofactor High Potency Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms of Vitamin B9 & B12 (60 Capsules 60 Servings)
- Price
- $21.67
- Rating
- 4.6/5
- Reviews
- 9,407
- Age
- 5y ago
Trending
estimated 90-day click momentum
Ortho Molecular Ortho B Complex 90
- Price
- $67.00
- Rating
- 5.0/5
- Reviews
- 10
- Age
- 15y ago

Designs for Health Homocysteine Supreme - Methylated B Vitamins with Riboflavin B6 B12 Folate L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (60 Capsules)
- Price
- $33.99
- Rating
- 4.8/5
- Reviews
- 949
- Age
- 5y ago

Nutricost Methylated Vitamin B Complex 120 Capsules 60 Servings
- Price
- $15.65
- Rating
- 4.6/5
- Reviews
- 377
- Age
- 1y ago

Metagenics MethylCare - Folate L-5-MTHF Methyl B12 B6 NAC & Betaine HCl - Supports Homocysteine Metabolism Methylation & Heart Health - Non-GMO & Gluten-Free - 120 Capsules
- Price
- $44.23
- Rating
- 4.8/5
- Reviews
- 325
- Age
- 8y ago

Micro Ingredients L Methylfolate 15mg 240 Softgels | Active 5-MTHF with B6 & Methyl B12 | Methylated Vitamin B9 with Coconut Oil
- Price
- $28.48
- Rating
- 4.8/5
- Reviews
- 289
- Age
- 1y ago
Newest
by launch date
Micro Ingredients L Methylfolate 15mg 240 Softgels | Active 5-MTHF with B6 & Methyl B12 | Methylated Vitamin B9 with Coconut Oil
- Price
- $28.48
- Rating
- 4.8/5
- Reviews
- 289
- Age
- 1y ago

Nutricost Methylated Vitamin B Complex 120 Capsules 60 Servings
- Price
- $15.65
- Rating
- 4.6/5
- Reviews
- 377
- Age
- 1y ago

Micro Ingredients Pure Methylated B Complex 240 Capsules | 11-in-1 Formula with Methylfolate B12 Thiamin Inositol Choline & Fat Soluble Vitamin C | Clean Ingredients Without Fillers | Non-GMO
- Price
- $24.65
- Rating
- 4.7/5
- Reviews
- 1,488
- Age
- 1y ago

L Methyl Folate 1000 mcg Plus Methyl B12 Cofactor Active 5-MTHF Form - Supports Mood Methylation Cognition Highly Bioavailable Bioactive Forms of Vitamin B9 & B12 (60 Capsules 60 Servings)
- Price
- $17.83
- Rating
- 4.6/5
- Reviews
- 4,077
- Age
- 1y ago

Designs for Health Homocysteine Supreme - Methylated B Vitamins with Riboflavin B6 B12 Folate L-Serine & TMG for Brain Support & Heart Health - Methylated Multivitamin (60 Capsules)
- Price
- $33.99
- Rating
- 4.8/5
- Reviews
- 949
- Age
- 5y ago
Competition
Competition: brands, sellers & click share
The top 5 products take an estimated 63% of clicks. Leaders hold, but buyers still shop past them.
Brands
13 falling
Sellers
37
Est. top-5 brand share
70%
Top 20: 100%
Est. top-5 click share
63%
Top 20: 100%
Open market
22%
- Ortho Molecular Products21%
- THORNE20%
- Triquetra Health10%
- Pure Encapsulations9%
- Pure Therapro Rx9%
- Micro Ingredients8%
Demand
Methyl Cpg search demand
Weekly searches over the year, seasonality beneath. Pick a range.
Peak months: Jan, Sep, Oct, Nov · busiest ÷ quietest = 2.4×
Reviews and returns
What reviews say buyers love and hate about Methyl Cpg
We read the reviews and the return reasons for every product selling here.
“Unless you've been specifically instructed by a doctor to take this high of a dosage”
Every topic
Every topic buyers talk about, one row each.
Red shows the share of negative reviews and green the share of positive reviews, biggest topic first. Open a row to read what they wrote.
22 topics
Keep looking
Related niches
Niches in the same category that score near this one. Research these next.
Best Flapen score
The highest-scoring niches we track right now, across every category.
FAQ
Common Methyl Cpg questions
Answered from the same tracked data.
Figures on this page are estimates modeled from public Amazon pages and third-party keyword data. Amazon does not supply them, and no connected seller's data is used. How we handle Amazon data









