Is lysine profitable to sell on Amazon United States?

The niche generates $6.9M/yr across 15 tracked products. 90-day search growth is -2.8%. Flapen's verdict: Worth a look (55/100).

How competitive is the lysine niche?

10 brands and 560 sellers compete. The top 5 products take 76% of clicks and top 5 brands hold 84% of demand.

What do buyers complain about in lysine?

Top complaints mined from reviews: Size-Overall, Ease Of Chewing/Swallowing, Dosage. The return rate is 0.0%.

When does demand for lysine peak?

Demand peaks in Dec; the busiest month runs 1.6× the quietest.

What does it cost to enter the lysine niche?

Listings span $6.46–$39.41; the average listing price is $15.62 (sweet spot $15–$100). The average incumbent carries 10,535 reviews — the moat a new listing must climb.

Lysine

Worth a look

Shows low returns (0.0%), but a concentrated shelf (top 5 take 76% of clicks) keeps it on the watch list.

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Market size

Incredible$6.9M

$6.9M/yr · 2.4M searches

Conversion

Incredible18.6%

search→purchase rate — share of searches ending in a sale

Avg price

Great$15.62

avg listing price — sweet spot $15–$100

Price range

Good$6.46–$39.41

cheapest to priciest tracked listing — scored on the share inside $15–$100

Brand share

Okay84%

top-5 brand share — brands hold most of the demand

Growth

Bad-2.8%

90-day search growth — must beat 0% to launch

Quality gap

Bad4.7★

avg incumbent rating — lower means beatable quality

Review moat

Bad10,535.13

avg incumbent reviews — the moat a new listing must climb

Competition

Bad76%

top-5 click share — a locked-up shelf

Is lysine profitable on Amazon?

According to Flapen's Amazon United States niche tracking, lysine is a $6.9M/yr Amazon United States market (2.4M searches/yr). The top 5 brands hold 84% of demand. Demand peaks in Dec. Verdict: Worth a look — 55/100.

Data updated Jul 25, 2026 · scored weekly · How we score niches

lysine market size & sales

Units sold, revenue, conversion and listing quality across the tracked shelf.

Units sold / yr: 400K–500K; avg 30,000–40,000/product
Revenue / yr: $6.2M–$7.8M; units × avg price
Conversion rate: 18.6%
Avg BSR: #89
Page quality: 0%
Prime: 100%
Sponsored: 87%
Out of stock: 0.0%
Avg brand age: 72 months
Avg seller age: 157 days

Competition: brands, sellers & click share

The top 5 products capture 76% of clicks — a locked-up shelf that new listings rarely crack.

Brands

10 falling

Sellers

560

Top-5 brand share

84%

Top 20: 100%

Top-5 click share

76%

Top 20: 100%

Open market

11%

NOW Foods32%
Pure Encapsulations23%
Nature Made14%
Bronson11%
Nutricost5%
THORNE5%
Open — no brand owns it (4 brands, 11%)

lysine demand & seasonality

Weekly Amazon search volume, last 104 weeks — -2.8% search growth over the last 90 days.

Peak months: Dec · busiest ÷ quietest = 1.6×

Open Trend

Top lysine search terms shoppers use

The exact queries shoppers type, with yearly volume, growth and conversion.

lysine920K/yr -7.1%15.6% conv.
l lysine402K/yr +9.3%13.6% conv.
l-lysine283K/yr +6.1%12.1% conv.
lysine 1000mg capsules279K/yr -3.2%16.8% conv.
l lysine 1000mg capsules136K/yr +4.3%15.3% conv.
l-lysine 1000mg capsules83K/yr -4.4%14.3% conv.
lysine supplement106K/yr -34.5%11.4% conv.
llysine27K/yr +13.8%14.0% conv.
lysine capsules24K/yr +4.3%5.9% conv.
lisina22K/yr -12.4%3.0% conv.

All search terms

Top lysine products & what they sell for

Every tracked product — its share of the shelf, its review moat, and what it sells for.

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 15 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

NOW Foods Supplements (L-Lysine Hydrochloride) 1 000 mg Double Strength Amino Acid 100 Tablets

NOW Foods$8.444.6★38,103 rev

Pure Encapsulations L-Lysine - Essential Amino Acid Supplement for Immune Support & Gum Lip Health* - with L-Lysine HCl - 90 Capsules

Pure Encapsulations$14.854.8★5,688 rev

Nature Made L-Lysine 1000 mg Dietary L-Lysine Supplements 60 Tablets 60 Day Supply

Nature Made$6.464.6★12,920 rev

Bronson L-Lysine Defense Immune Support Complex 1500 MG L-Lysine Plus Olive Leaf Garlic Vitamin C and Zinc - Non-GMO 90 Vegetarian Capsules

Bronson$9.884.7★6,618 rev

THORNE - Lysine - Supports Immune Skin & Bone Health - Promotes Collagen Formation* - L-Lysine Amino Acid Supplement - Third-Party Certified - Gluten Dairy & Soy-Free - 60 Capsules

THORNE$14.524.7★1,865 rev

Newest

by launch date

Pure L-Lysine 2 000mg 300 Veggie Capsules | Maximum Potency Easily Absorbed Free Form | Essential Amino Acid for Collagen Lip & Immune Support | Clean Ingredients Without Fillers

Micro Ingredients$17.12515 rev

1y ago

Bronson L-Lysine Extra Strength 1000 MG per Tablet High Potency Immune Support & Supports Collagen Synthesis Non-GMO 100 Vegetarian Tablets

Bronson$10.021,698 rev

3y ago

Bronson L-Lysine Defense Immune Support Complex 1500 MG L-Lysine Plus Olive Leaf Garlic Vitamin C and Zinc - Non-GMO 90 Vegetarian Capsules

Bronson$9.886,618 rev

6y ago

Nutricost L-Lysine 1000mg 250 Capsules - 500mg Per Cap Gluten Free Non-GMO

Nutricost$14.757,057 rev

8y ago

NOW Foods Supplements L-Lysine (L-Lysine Hydrochloride) 1 000 mg Double Strength Amino Acid 250 Tablets

NOW Foods$18.4338,103 rev

8y ago

What reviews say buyers love and hate about lysine

What buyers praise and complain about, mined from review topics.

What buyers love

Quality-Overall17%

“Good quality and trusted brand”

Value For Money10%

“Great value”

Efficiency10%

“Works fast and well”

Cold Relief8%

“Super Effective for Cold Sores”

Vitamin5%

“Great vitamin supplement”

Advertised Vs Actual Product5%

“exactly as advertised”

Fever Relief4%

“Keeps fever blisters away”

Immunity Booster4%

“boost my immune system”

Ease Of Chewing/Swallowing3%

“Im able to swallow without choking”

Skin Health3%

“Has helped clear my acne”

What buyers complain about

Size-Overall22%

“Tablets are rather large”

Ease Of Chewing/Swallowing8%

“Not sure it will get into mouth”

Dosage7%

“They don't do well in the bottle”

Functionality-Overall6%

“It didnt help”

Value For Money4%

“waste of money”

Allergies4%

“Found out I had an allergic reaction to this supplement”

Pain Relief-Overall3%

“pain behind my eyes”

Ingredients-Overall2%

“Without checking the ingredients i ordered this”

Side Effects2%

“As well as caused stomach upset”

Ease Of Use2%

“were too difficult for me to swallow”

Top return reasons

Functionality-Overall29%

Advertised Vs Actual Product20%

Value For Money12%

Size-Overall6%

Ingredients-Overall5%

Smell5%

Ease Of Chewing/Swallowing4%

Vegan/Organic2%

Defective Material/Parts2%

Suitability Hot Weather2%

Common lysine questions

Is lysine profitable to sell on Amazon United States?: The niche generates $6.9M/yr across 15 tracked products. 90-day search growth is -2.8%. Flapen's verdict: Worth a look (55/100).
How competitive is the lysine niche?: 10 brands and 560 sellers compete. The top 5 products take 76% of clicks and top 5 brands hold 84% of demand.
What do buyers complain about in lysine?: Top complaints mined from reviews: Size-Overall, Ease Of Chewing/Swallowing, Dosage. The return rate is 0.0%.
When does demand for lysine peak?: Demand peaks in Dec; the busiest month runs 1.6× the quietest.
What does it cost to enter the lysine niche?: Listings span $6.46–$39.41; the average listing price is $15.62 (sweet spot $15–$100). The average incumbent carries 10,535 reviews — the moat a new listing must climb.