Is lipase profitable to sell on Amazon United States?

The niche generates $244K/yr across 17 tracked products. 0 of 1 products launched in the last 360 days are still selling. 90-day search growth is +1.6%. Flapen's verdict: Worth a look (54/100).

How competitive is the lipase niche?

14 brands and 135 sellers compete. The top 5 products take 67% of clicks and top 5 brands hold 77% of demand.

What do buyers complain about in lipase?

Top complaints mined from reviews: Functionality-Overall, Regulates Digestion, Acid Regulator/Stomach Ache Relief. The return rate is 0.0%.

When does demand for lipase peak?

Demand peaks in Jan; the busiest month runs 1.6× the quietest.

What does it cost to enter the lipase niche?

Listings span $11.86–$67.11; the average listing price is $25.77 (sweet spot $15–$100). The average incumbent carries 4,033 reviews — the moat a new listing must climb.

Lipase

Worth a look

Shows low returns (0.0%), but a deep review moat (4,033 avg reviews) keeps it on the watch list.

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Avg price

Incredible$25.77

avg listing price — sweet spot $15–$100

Price range

Great$11.86–$67.11

cheapest to priciest tracked listing — scored on the share inside $15–$100

Conversion

Great7.7%

search→purchase rate — share of searches ending in a sale

Quality gap

Good4.4★

avg incumbent rating — lower means beatable quality

Market size

Okay$244K

$244K/yr · 123K searches

Brand share

Okay77%

top-5 brand share — brands hold most of the demand

Competition

Okay67%

top-5 click share — leaders hold, buyers still browse

Growth

Okay+1.6%

90-day search growth — must beat 0% to launch

Review moat

Bad4,033.29

avg incumbent reviews — the moat a new listing must climb

Is lipase profitable on Amazon?

According to Flapen's Amazon United States niche tracking, lipase is a $244K/yr Amazon United States market (123K searches/yr). The top 5 brands hold 77% of demand. Demand peaks in Jan. Verdict: Worth a look — 54/100.

Data updated Jul 26, 2026 · scored weekly · How we score niches

lipase market size & sales

Units sold, revenue, conversion and listing quality across the tracked shelf.

Units sold / yr: 8K–10K; avg 500–750/product
Revenue / yr: $206K–$258K; units × avg price
Conversion rate: 7.7%
Avg BSR: #227
Page quality: 0%
Prime: 94%
Sponsored: 88%
Out of stock: 0.0%
Avg brand age: 99 months
Avg seller age: 163 days

Competition: brands, sellers & click share

The top 5 products take 67% of clicks — established leaders, but buyers still shop beyond them.

Brands

14 rising

Sellers

135

Top-5 brand share

77%

Top 20: 100%

Top-5 click share

67%

Top 20: 100%

Open market

19%

Enzymedica45%
Integrative Therapeutics17%
NOW Foods6%
Biomedic Labs RX5%
Double Wood Supplements4%
AST Enzymes4%

lipase demand & seasonality

Weekly Amazon search volume, last 104 weeks — +1.6% search growth over the last 90 days.

Peak months: Jan · busiest ÷ quietest = 1.6×

Open Trend

Top lipase search terms shoppers use

The exact queries shoppers type, with yearly volume, growth and conversion.

lipase49K/yr -1.2%4.9% conv.
lipase digestive enzymes32K/yr -7.8%6.4% conv.
lypo gold15K/yr +23.2%14.9% conv.
lipase enzymes for digestion4K/yr +60.4%0.5% conv.
lipase enzymes7K/yr -19.0%4.3% conv.
lipase supplement5K/yr +1.8%3.0% conv.
lipase enzyme3K/yr -0.2%2.9% conv.
enzymedica lypo gold3K/yr +18.0%15.7% conv.
lipo gold2K/yr +72.2%12.2% conv.
lypo gold enzymedica3K/yr -28.1%19.2% conv.

All search terms

Top lipase products & what they sell for

Every tracked product — its share of the shelf, its review moat, and what it sells for.

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 17 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Enzymedica Lypo Gold - Protease Amylase & Lipase Digestive Enzymes for Women & Men Enzyme Supplement for Fat Digestion Gut Health & Gallbladder Support Helps Gas & Bloating Gluten Free - 60 Caps

Enzymedica$22.374.4★1,840 rev

Integrative Therapeutics Lipase Concentrate-HP - Digestive Enzyme Supplement for the Digestion of Fats* - Nutrient Absorption & GI Tract Health Support* - Dairy-Free & Vegan - 90 Count (45 Servings)

Integrative Therapeutics$24.714.4★1,346 rev

Enzymedica Lypo Gold - Protease Amylase & Lipase Digestive Enzymes for Women & Men Enzyme Supplement for Fat Digestion Gut Health & Gallbladder Support Helps Gas & Bloating Gluten Free - 240 Caps

Enzymedica$67.114.4★1,840 rev

Enzymedica Lypo Gold - Protease Amylase & Lipase Digestive Enzymes for Women & Men Enzyme Supplement for Fat Digestion Gut Health & Gallbladder Support Helps Gas & Bloating Gluten Free - 120 Caps

Enzymedica$35.934.4★1,840 rev

Biomedic Labs RX Gallbladder Formula Lipase Protease and Amylase Digestive Enzymes to Reduce Bloating - Vegetarian Formula 60 Veg Capsules

Biomedic Labs RX$13.834.2★104 rev

Newest

by launch date

Arthur Andrew Medical Lipagest - Concentrated Lipase Enzyme - 20 000 FIP - Optimal Digestion of Fats - Nutrient Absorption - Gallblader & Keto Support - Dairy-Free & Vegan

Arthur Andrew Medical$23.9916 rev

10mo ago

Physicians CHOICE Digestive Enzymes for Bloating & Digestion - Fast-Acting 16 Enzyme Formula with Organic Prebiotics & Probiotics for Gut & Digestive Health - Meal Time Discomfort Relief - 60 CT

Physician's CHOICE$19.0818,747 rev

3y ago

Biomedic Labs RX Gallbladder Formula Lipase Protease and Amylase Digestive Enzymes to Reduce Bloating - Vegetarian Formula 60 Veg Capsules

Biomedic Labs RX$13.83104 rev

4y ago

Digestive Enzymes - 800mg Blend of All 10 Most Essential Digestive and Pancreatic Enzymes (Amylase Lipase Bromelain Lactase Papain Protease Cellulase Maltase Invertase) by Double Wood

Double Wood Supplements$18.123,836 rev

5y ago

BIOptimizers MassZymes - Complete Digestive Enzymes Supplement for Gut Health - Bloating Relief for Men and Women - Lipase Amylase Bromelain Digestive Enzymes (30 Capsules)

BIOptimizers$18.722,514 rev

6y ago

What reviews say buyers love and hate about lipase

What buyers praise and complain about, mined from review topics.

What buyers love

Regulates Digestion33%

“Digestion Improved”

Quality-Overall14%

“Good product and very effective”

Efficiency12%

“Works Well”

Acid Regulator/Stomach Ache Relief8%

“Great for indigestion”

Value For Money3%

“reasonably priced”

Nutritional Content3%

“This supplement helps”

Advertised Vs Actual Product3%

“As advertised”

Vitamin2%

“Great supplement”

Weight Loss2%

“I have lost weight”

Ingredients-Overall1%

“Has all the needed ingredients”

What buyers complain about

Functionality-Overall18%

“Did not work”

Regulates Digestion13%

“I can't seem to digest anything anymore”

Acid Regulator/Stomach Ache Relief12%

“upsets your stomach”

Side Effects4%

“Made me sick”

Dosage4%

“Beware of dosage, it is 3 per meal, not 2”

Allergies4%

“Allergic to it”

Ingredients-Overall3%

“But they changed ingredients”

Pain Relief-Overall3%

“PAIN IS UNBAREABLE”

Value For Money3%

“Expensive”

Nutritional Content2%

“its hard for me avoid certain foods 100%”

Top return reasons

Functionality-Overall38%

Value For Money15%

Advertised Vs Actual Product10%

Smell5%

Joint Pain5%

Side Effects5%

Accuracy-Overall5%

Stale/Rotten/Spoiled5%

Color5%

Acid Regulator/Stomach Ache Relief5%

Common lipase questions

Is lipase profitable to sell on Amazon United States?: The niche generates $244K/yr across 17 tracked products. 0 of 1 products launched in the last 360 days are still selling. 90-day search growth is +1.6%. Flapen's verdict: Worth a look (54/100).
How competitive is the lipase niche?: 14 brands and 135 sellers compete. The top 5 products take 67% of clicks and top 5 brands hold 77% of demand.
What do buyers complain about in lipase?: Top complaints mined from reviews: Functionality-Overall, Regulates Digestion, Acid Regulator/Stomach Ache Relief. The return rate is 0.0%.
When does demand for lipase peak?: Demand peaks in Jan; the busiest month runs 1.6× the quietest.
What does it cost to enter the lipase niche?: Listings span $11.86–$67.11; the average listing price is $25.77 (sweet spot $15–$100). The average incumbent carries 4,033 reviews — the moat a new listing must climb.