Interstitial Cystitis Pain Relief
Skip itA small market ($22K/yr) — this niche doesn't clear our bar today.
Returns
Incredible0.0%return rate — above 5% kills the launch gate
Avg price
Incredible$38.10avg listing price — sweet spot $15–$100
Price range
Great$9.74–$64.01cheapest to priciest tracked listing — scored on the share inside $15–$100
Quality gap
Good4.3★avg incumbent rating — lower means beatable quality
Review moat
Good1,000.5avg incumbent reviews — the moat a new listing must climb
Conversion
Okay3.8%search→purchase rate — share of searches ending in a sale
Brand share
Okay83%top-5 brand share — brands hold most of the demand
Growth
Okay+8.8%90-day search growth — must beat 0% to launch
Competition
Bad81%top-5 click share — a locked-up shelf
Market size
Bad$22K$22K/yr · 15K searches
Is interstitial cystitis pain relief profitable on Amazon?
According to Flapen's Amazon United States niche tracking, interstitial cystitis pain relief is a $22K/yr Amazon United States market (15K searches/yr). The top 5 brands hold 83% of demand. Demand peaks in Jan–Aug–Sep–Oct–Nov. Verdict: Skip it — 46/100.
Data updated Jul 12, 2026 · scored weekly · How we score niches
interstitial cystitis pain relief market size & sales
Units sold, revenue, conversion and listing quality across the tracked shelf.- Units sold / yr
- 1K–1K
- avg 100–250/product
- Revenue / yr
- $38K–$48K
- units × avg price
- Conversion rate
- 3.8%
- Avg BSR
- #3,193
- Page quality
- 0%
- Prime
- 90%
- Sponsored
- 100%
- Out of stock
- 9.1%
- Avg brand age
- 91 months
- Avg seller age
- 184 days
Competition: brands, sellers & click share
The top 5 products capture 81% of clicks — a locked-up shelf that new listings rarely crack.Brands
9 falling
Sellers
29
Top-5 brand share
83%
Top 20: 100%
Top-5 click share
81%
Top 20: 100%
Open market
11%
- CystoMend37%
- Real Science Nutrition15%
- Algonot12%
- Douglas Laboratories10%
- Cystex8%
- SUNN BIOLABS6%
- Open — no brand owns it (3 brands, 11%)
interstitial cystitis pain relief demand & seasonality
Weekly Amazon search volume, last 104 weeks — +8.8% search growth over the last 90 days.Peak months: Jan, Aug, Sep, Oct, Nov · busiest ÷ quietest = 2.6×
Top interstitial cystitis pain relief products & what they sell for
Every tracked product — its share of the shelf, its review moat, and what it sells for.Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.
All 10 tracked products in this niche — three views at once, no toggling.
Top sellers
by 90-day click share
CystoMend Bladder & Pelvic Discomfort Formula (High Potency) - Supports Less Flares & Urgency* - Premium Bladder Support for Women & Men - USA Manufactured & Third-Party Tested - 180 Capsules
CystoMend$56.594.5★267 rev
Real Science IntersCyst Miracle All Natural Supplement for Interstitial Cystitis Relief and Constipation with Vitamins C D B12 & K + Nitric Oxide Support Bladder & Kidney Health Support 60 Caps
Real Science Nutrition$34.684.0★65 rev
Algonot FibroProtek Physician Recommended with Exclusive Combination of Ingredients Including Luteolin Quercetin Carnitine Olive Pomace Oil 60 Capsules
Algonot$48.674.2★56 rev
Douglas Laboratories Cysto Renew | Supplement to Support a Calm and Healthy Functioning Bladder* | 120 Capsules
Douglas Laboratories$64.014.1★223 rev
CYSTUROL Bladder Support Supplement | Interstitial Cystitis (IC) | Bladder Pain | Urinary Tract Health | Clinically Studied Formula for Bladder Inflammation UTI Mast Cell Support & Urinary Urgency
SUNN BIOLABS$49.034.1★45 rev
Newest
by launch date
Cystex 3-in-1 Urinary Tract Probiotic for Women - Prebiotic Probiotic & Cranberry Supplement for UTI & Yeast Infection Support - Vaginal pH Balance & Flora Support - Urinary Health - 30 Capsules
Cystex$19.38320 rev
SOLV NATURALS CYSTASOLV Bladder & Pelvic Discomfort Formula - Enjoy Less Urgency & Flares* with Daily IC/BPS UTI Support Premium Bladder & Urinary Support for Women & Men - 60 Vegan Capsules
SOLV NATURALS$49.3166 rev
LifeSeasons Femetry Bladder Acid Control - Support for Interstitial Cystitis - Reduce Urine Acidity in The Bladder - Eases Flares Caused by Eating or Drinking Acidic Foods - 60 Tablets
LifeSeasons$20.8640 rev
Real Science IntersCyst Miracle All Natural Supplement for Interstitial Cystitis Relief and Constipation with Vitamins C D B12 & K + Nitric Oxide Support Bladder & Kidney Health Support 60 Caps
Real Science Nutrition$34.6865 rev
CYSTUROL Bladder Support Supplement | Interstitial Cystitis (IC) | Bladder Pain | Urinary Tract Health | Clinically Studied Formula for Bladder Inflammation UTI Mast Cell Support & Urinary Urgency
SUNN BIOLABS$49.0345 rev
Trending
90-day click momentumDouglas Laboratories Cysto Renew | Supplement to Support a Calm and Healthy Functioning Bladder* | 120 Capsules
Douglas Laboratories$64.014.1★
Cystex 3-in-1 Urinary Tract Probiotic for Women - Prebiotic Probiotic & Cranberry Supplement for UTI & Yeast Infection Support - Vaginal pH Balance & Flora Support - Urinary Health - 30 Capsules
Cystex$19.384.6★
Algonot FibroProtek Physician Recommended with Exclusive Combination of Ingredients Including Luteolin Quercetin Carnitine Olive Pomace Oil 60 Capsules
Algonot$48.674.2★
Real Science IntersCyst Miracle All Natural Supplement for Interstitial Cystitis Relief and Constipation with Vitamins C D B12 & K + Nitric Oxide Support Bladder & Kidney Health Support 60 Caps
Real Science Nutrition$34.684.0★
SOLV NATURALS CYSTASOLV Bladder & Pelvic Discomfort Formula - Enjoy Less Urgency & Flares* with Daily IC/BPS UTI Support Premium Bladder & Urinary Support for Women & Men - 60 Vegan Capsules
SOLV NATURALS$49.314.1★
What reviews say buyers love and hate about interstitial cystitis pain relief
What buyers praise and complain about, mined from review topics.What buyers love
“it works really well for utis until you get to the doctor”
“Very good reviews”
“Incredible Value for Money”
“Exactly as pictured, described and expected”
“Excellent alternative for UTI”
“Helps stomach as well as bladder”
“Prelief has helped me so much with acid reduction”
“Bladder pain, relief”
“This product has been a lifesaver for my Interstitial cystitis. IC”
“Its reliable, effective, and very easy to use”
What buyers complain about
“Did not work”
“Zero pain relief for me”
“colorless not like previous orange urine turn”
“I can't afford almost $26.00 for a small bottle”
“nsaid for inflammation”
“doesn't change the color of my urine unlike similar products”
“I can't afford almost $26.00 for a small bottle”
“drinks were causing my bladder problems”
“I am highly allergic to NSAIDs”
“These pills are huge”
Top return reasons
Common interstitial cystitis pain relief questions
- Is interstitial cystitis pain relief profitable to sell on Amazon United States?
- The niche generates $22K/yr across 10 tracked products. 90-day search growth is +8.8%. Flapen's verdict: Skip it (46/100).
- How competitive is the interstitial cystitis pain relief niche?
- 9 brands and 29 sellers compete. The top 5 products take 81% of clicks and top 5 brands hold 83% of demand.
- What do buyers complain about in interstitial cystitis pain relief?
- Top complaints mined from reviews: Functionality-Overall, Pain Relief-Overall, Color. The return rate is 0.0%.
- When does demand for interstitial cystitis pain relief peak?
- Demand peaks in Jan–Aug–Sep–Oct–Nov; the busiest month runs 2.6× the quietest.
- What does it cost to enter the interstitial cystitis pain relief niche?
- Listings span $9.74–$64.01; the average listing price is $38.10 (sweet spot $15–$100). The average incumbent carries 1,001 reviews — the moat a new listing must climb.