Is endometriosis supplement profitable to sell on Amazon United States?

The niche generates $68K/yr across 12 tracked products. 90-day search growth is -10.2%. Flapen's verdict: Skip it (42/100).

How competitive is the endometriosis supplement niche?

11 brands and 21 sellers compete. The top 5 products take 78% of clicks and top 5 brands hold 83% of demand.

What do buyers complain about in endometriosis supplement?

Top complaints mined from reviews: Side Effects, Functionality-Overall, Dosage. The return rate is 0.1%.

What does it cost to enter the endometriosis supplement niche?

Listings span $13.19–$48.70; the average listing price is $26.36 (sweet spot $15–$100). The average incumbent carries 6,855 reviews — the moat a new listing must climb.

endometriosis supplement

Skip it

A small market ($68K/yr) — this niche doesn't clear our bar today.

Returns

Incredible0.1%

return rate — above 5% kills the launch gate

Avg price

Incredible$26.36

avg listing price — sweet spot $15–$100

Price range

Great$13.19–$48.70

cheapest to priciest tracked listing — scored on the share inside $15–$100

Quality gap

Good4.4★

avg incumbent rating — lower means beatable quality

Brand share

Okay83%

top-5 brand share — brands hold most of the demand

Conversion

Okay2.8%

search→purchase rate — share of searches ending in a sale

Review moat

Bad6,854.92

avg incumbent reviews — the moat a new listing must climb

Growth

Bad-10.2%

90-day search growth — must beat 0% to launch

Competition

Bad78%

top-5 click share — a locked-up shelf

Market size

Bad$68K

$68K/yr · 93K searches

According to Flapen's Amazon United States niche tracking, endometriosis supplement is a $68K/yr Amazon United States market (93K searches/yr). The top 5 brands hold 83% of demand. Verdict: Skip it — 42/100.

Data updated Jul 27, 2026 · scored weekly · How we score niches

endometriosis supplement market data

Units sold / yr: 2K–3K; avg 100–250/product
Revenue / yr: $53K–$66K; units × avg price
Conversion rate: 2.8%
Avg BSR: #23
Page quality: 0%
Prime: 100%
Sponsored: 83%
Out of stock: 0.4%
Avg brand age: 58 months
Avg seller age: 151 days

Competition & brand share

The top 5 products capture 78% of clicks — a locked-up shelf that new listings rarely crack.

Brands

11 falling

Sellers

Top-5 brand share

83%

Top 20: 100%

Top-5 click share

78%

Top 20: 100%

Open market

14%

Freshly Moms45%
SMNutrition14%
Daily Nouri12%
Santo Remedio8%
SMSHEALTHPRODUCTS.com4%
Natures Craft4%
Open — no brand owns it (5 brands, 14%)

Demand

Weekly Amazon search volume, last 33 weeks — -10.2% search growth over the last 90 days.

Open Trend

Top endometriosis supplement search terms

hormonal balance17K/yr +18.0%1.5% conv.
hormones10K/yr -4.0%0.4% conv.
osh hormonal balance and mood support8K/yr -3.7%9.1% conv.
female hormones7K/yr -10.2%1.1% conv.
hormonal5K/yr +45.9%0.5% conv.
hormonal balance and mood support5K/yr -7.2%6.8% conv.
regulador hormonal para mujer5K/yr +31.5%0.5% conv.
hormonas4K/yr -7.7%0.2% conv.
hormone vitamins for women6K/yr -27.7%1.0% conv.
hormone health4K/yr -37.5%0.3% conv.

All search terms

Top endometriosis supplement products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 12 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Freshly Moms$30.114.3★805 rev

Daily Nouri Hormone Balance Probiotics for Women | Supports Healthy Estrogen Metabolism Hormone & Cycle Health | Gut-Estrogen/Estrobolome Support | 7 Clinically Studied Strains + Plant-Based Omega

Daily Nouri$30.674.4★1,383 rev

DIM Supplement 200 mg | Estrogen Balance for Women & Men | Hormonal Acne Hormone Balance Menopause & Antioxidant Support | Doctor-Formulated & Clean Label Project Certified Diindolylmethane | 60 Ct

SMNutrition$24.204.4★30,062 rev

Santo Remedio Hormonal Balance for Women | Menopause Support for Hot Flashes Night Sweats & Mood Swings | Hormone-Free Formula with Siberian Rhubarb Chaste Tree & DIM | Doctor Juan Rivera Product

Santo Remedio$37.594.4★326 rev

Myo-Inositol & D-Chiro Inositol for Hormone Balance for Women | Fertility Ovarian Health & Cycle Support | Ideal 40:1 Ratio Myoinositol 2000mg & D Chiro 50mg | Ovarian Support Vitamins | 120 Ct.

SMNutrition$19.344.6★3,307 rev

Newest

by launch date

Santo Remedio Hormonal Balance for Women | Menopause Support for Hot Flashes Night Sweats & Mood Swings | Hormone-Free Formula with Siberian Rhubarb Chaste Tree & DIM | Doctor Juan Rivera Product

Santo Remedio$37.59326 rev

1y ago

Daily Nouri Hormone Balance Probiotics for Women | Supports Healthy Estrogen Metabolism Hormone & Cycle Health | Gut-Estrogen/Estrobolome Support | 7 Clinically Studied Strains + Plant-Based Omega

Daily Nouri$30.671,383 rev

1y ago

O Positiv FLO Ovarian Health Support - Hormone Balance for Women Supplement with DIM Myo & D-Chiro Inositol Folic Acid - Supports Healthy Ovulation Cycle Regularity - 30 Servings

O Positiv$35.832,875 rev

2y ago

Freshly Moms$30.11805 rev

3y ago

SOLARAY Female Hormone Blend SP-7C Herbal Support Hormonal Balance for Women with Black Cohosh Dong Quai Wild Yam and More Vegan Lab Verified 60-Day Guarantee 120 Servings 240 VegCaps

SOLARAY$19.351,798 rev

3y ago

What buyers say about endometriosis supplement

What buyers praise and complain about, mined from review topics.

What buyers love

Hormonal Balance14%

“Helps with hormonal acne”

Quality-Overall9%

“In all, it is a good quality product that is easy to use”

Menstrual Issues8%

“Menopausal support: Excellent”

Taste-Overall7%

“Taste great”

Fertility/Conception5%

“Helped me get pregnant”

Efficiency5%

“Works well”

Vitamin4%

“Vitamins”

Value For Money3%

“Worth it”

Side Effects3%

“I had no side effects”

Skin Health3%

“Great for acne treatments”

What buyers complain about

Side Effects13%

“BAD stomach cramps”

Functionality-Overall11%

“Didn't work on me”

Dosage6%

“the preferred dosage is not my preference”

Value For Money6%

“Not worth it”

Allergies5%

“Possible reaction”

Weight Loss4%

“No weight loss”

Taste-Overall3%

“However it does taste weird”

Sleep Quality3%

“Not sleeping well”

Stress/Anxiety3%

“It triggered my anxiety”

Acid Regulator/Stomach Ache Relief3%

“I started experiencing severe stomach pain”

Top return reasons

Functionality-Overall15%

Acid Regulator/Stomach Ache Relief6%

Vitamin6%

Advertised Vs Actual Product5%

Smell5%

Color Fading/Discoloration5%

Moist/Dry4%

Side Effects4%

Color3%

Size-Overall3%

Common questions

Is endometriosis supplement profitable to sell on Amazon United States?: The niche generates $68K/yr across 12 tracked products. 90-day search growth is -10.2%. Flapen's verdict: Skip it (42/100).
How competitive is the endometriosis supplement niche?: 11 brands and 21 sellers compete. The top 5 products take 78% of clicks and top 5 brands hold 83% of demand.
What do buyers complain about in endometriosis supplement?: Top complaints mined from reviews: Side Effects, Functionality-Overall, Dosage. The return rate is 0.1%.
What does it cost to enter the endometriosis supplement niche?: Listings span $13.19–$48.70; the average listing price is $26.36 (sweet spot $15–$100). The average incumbent carries 6,855 reviews — the moat a new listing must climb.