Is diphenhydramine 50mg 1000 capsules profitable to sell on Amazon United States?

The niche generates $9K/yr across 9 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is -7.7%. Flapen's verdict: Skip it (41/100).

How competitive is the diphenhydramine 50mg 1000 capsules niche?

9 brands and 14 sellers compete. The top 5 products take 79% of clicks and top 5 brands hold 79% of demand.

What do buyers complain about in diphenhydramine 50mg 1000 capsules?

Top complaints mined from reviews: Sleep Quality, Functionality-Overall, Dosage. The return rate is 0.0%.

When does demand for diphenhydramine 50mg 1000 capsules peak?

Demand peaks in May; the busiest month runs 3.2× the quietest.

What does it cost to enter the diphenhydramine 50mg 1000 capsules niche?

Listings span $10.07–$29.46; the average listing price is $17.47 (sweet spot $15–$100). The average incumbent carries 5,616 reviews — the moat a new listing must climb.

diphenhydramine 50mg 1000 capsules

Skip it

A small market ($9K/yr) — this niche doesn't clear our bar today.

Conversion

Incredible20.7%

search→purchase rate — share of searches ending in a sale

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Avg price

Great$17.47

avg listing price — sweet spot $15–$100

Price range

Great$10.07–$29.46

cheapest to priciest tracked listing — scored on the share inside $15–$100

Brand share

Okay79%

top-5 brand share — brands hold most of the demand

Review moat

Bad5,616.33

avg incumbent reviews — the moat a new listing must climb

Growth

Bad-7.7%

90-day search growth — must beat 0% to launch

Competition

Bad79%

top-5 click share — a locked-up shelf

Quality gap

Bad4.7★

avg incumbent rating — lower means beatable quality

Market size

Bad$9K

$9K/yr · 2K searches

According to Flapen's Amazon United States niche tracking, diphenhydramine 50mg 1000 capsules is a $9K/yr Amazon United States market (2K searches/yr). The top 5 brands hold 79% of demand. Demand peaks in May. Verdict: Skip it — 41/100.

Data updated Jul 11, 2026 · scored weekly · How we score niches

diphenhydramine 50mg 1000 capsules market data

Units sold / yr: 250–500; avg 0–100/product
Revenue / yr: $4K–$9K; units × avg price
Conversion rate: 20.7%
Avg BSR: #192
Page quality: 0%
Prime: 89%
Sponsored: 89%
Out of stock: 10.4%
Avg brand age: 84 months
Avg seller age: 192 days

Competition & brand share

The top 5 products capture 79% of clicks — a locked-up shelf that new listings rarely crack.

Brands

9 rising

Sellers

Top-5 brand share

79%

Top 20: 100%

Top-5 click share

79%

Top 20: 100%

Open market

15%

WELMATE26%
SDA LABORATORIES21%
Wonder Laboratories13%
P Puregen Labs11%
HEALTH LFE8%
GenCare6%
Open — no brand owns it (3 brands, 15%)

Demand & seasonality

Weekly Amazon search volume, last 103 weeks — -7.7% search growth over the last 90 days.

Peak months: May · busiest ÷ quietest = 3.2×

Open Trend

Top diphenhydramine 50mg 1000 capsules products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 9 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

WELMATE Allergy Relief - Diphenhydramine 50 mg - 1000 Count Capsules - Antihistamine - Allergy & Cold Symptoms - Sneezing Runny Nose Itchy Eyes & Throat

WELMATE$24.634.7★677 rev

SDA LABORATORIES Diphenhydramine 50mg Allergy Relief Fast-Acting Indoor & Outdoor Antihistamine Symptom Control 1000 Count (1 Bottle)

SDA LABORATORIES$29.464.8★944 rev

Wonder Laboratories Pharbedryl Diphenhydramine HCI 50 Mg Allergy Medicine and Antihistamine y - 1000 Capsules #3639

Wonder Laboratories$22.674.8★45 rev

Puregen Labs Diphenhydramine HCl 50 mg Capsules 1000 Count Antihistamine I Allergy & Cold Symptoms Relief - Sneezing Runny Nose Itchy Eyes & Throat

P Puregen Labs$24.765.0★5 rev

HEALTH LFE Allergy Relief Medicine Diphenhydramine HCl Caplets 25 mg | Children and Adults | Relieves Sneezing Runny Nose Hay Fever Symptoms Itchy Eyes and Throat (Large 1000 Count)

HEALTH LFE$10.124.8★2,715 rev

Newest

by launch date

Puregen Labs Diphenhydramine HCl 50 mg Capsules 1000 Count Antihistamine I Allergy & Cold Symptoms Relief - Sneezing Runny Nose Itchy Eyes & Throat

P Puregen Labs$24.765 rev

2mo ago

WELMATE Allergy Relief - Diphenhydramine 50 mg - 1000 Count Capsules - Antihistamine - Allergy & Cold Symptoms - Sneezing Runny Nose Itchy Eyes & Throat

WELMATE$24.63677 rev

2y ago

RIGHT REMEDIES Nighttime Sleep Aid Softgels (275 softgels) Diphenhydramine HCI 50 mg Fall Asleep Fast Supports Deeper Restful Sleep

RIGHT REMEDIES$11.091,292 rev

3y ago

MedPlus Allergy Relief Medicine Diphenhydramine HCl 25 mg 1000 Tablets Antihistamine Relief for Indoor & Outdoor Allergies Made in USA

Generic$10.331,330 rev

3y ago

HEALTH LFE Allergy Relief Medicine Diphenhydramine HCl Caplets 25 mg | Children and Adults | Relieves Sneezing Runny Nose Hay Fever Symptoms Itchy Eyes and Throat (Large 1000 Count)

HEALTH LFE$10.122,715 rev

5y ago

What buyers say about diphenhydramine 50mg 1000 capsules

What buyers praise and complain about, mined from review topics.

What buyers love

Sleep Quality30%

“Great night sleep”

Value For Money25%

“Fair price”

Quality-Overall9%

“the tablets have been consistent in quality”

Efficiency6%

“Works just as intended”

Advertised Vs Actual Product4%

“Just as advertised”

Dosage4%

“Use it daily”

Allergies4%

“These are perfect for allergies”

Ease Of Chewing/Swallowing3%

“I swallowed them fine”

Side Effects1%

“have no side effects”

Ease Of Use1%

“Works well easy to take works within 30 minutes”

What buyers complain about

Sleep Quality23%

“Now I won't sleep at all”

Functionality-Overall16%

“Didn't work for me”

Dosage7%

“These pills do not work at all”

Allergies7%

“Weird reaction”

Taste-Overall3%

“for some reason they are soft and mushy instead of hard like usual and they have a medicine taste to them makes me wonder if some of them broke open and got wet and that's why they're so soft and taste the way they do”

Quality-Overall3%

“Very inconsistent, not sure about the quality control”

Size-Overall3%

“Cap is loose fitting”

Strength3%

“Ineffective, just waste of money”

Smell2%

“The pills have a chemical smell and chemical taste”

Advertised Vs Actual Product2%

“Just be aware of these are capsules, not tablets”

Common questions

Is diphenhydramine 50mg 1000 capsules profitable to sell on Amazon United States?: The niche generates $9K/yr across 9 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is -7.7%. Flapen's verdict: Skip it (41/100).
How competitive is the diphenhydramine 50mg 1000 capsules niche?: 9 brands and 14 sellers compete. The top 5 products take 79% of clicks and top 5 brands hold 79% of demand.
What do buyers complain about in diphenhydramine 50mg 1000 capsules?: Top complaints mined from reviews: Sleep Quality, Functionality-Overall, Dosage. The return rate is 0.0%.
When does demand for diphenhydramine 50mg 1000 capsules peak?: Demand peaks in May; the busiest month runs 3.2× the quietest.
What does it cost to enter the diphenhydramine 50mg 1000 capsules niche?: Listings span $10.07–$29.46; the average listing price is $17.47 (sweet spot $15–$100). The average incumbent carries 5,616 reviews — the moat a new listing must climb.