Is acetaminophen 500mg profitable to sell on Amazon United States?

The niche generates $260K/yr across 16 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is -8.0%. Flapen's verdict: Skip it (43/100).

How competitive is the acetaminophen 500mg niche?

8 brands and 75 sellers compete. The top 5 products take 71% of clicks and top 5 brands hold 93% of demand.

What do buyers complain about in acetaminophen 500mg?

Top complaints mined from reviews: Functionality-Overall, Ease Of Chewing/Swallowing, Size-Overall. The return rate is 0.0%.

When does demand for acetaminophen 500mg peak?

Demand peaks in Sep–Oct; the busiest month runs 2.6× the quietest.

What does it cost to enter the acetaminophen 500mg niche?

Listings span $3.26–$30.70; the average listing price is $12.65 (sweet spot $15–$100). The average incumbent carries 35,444 reviews — the moat a new listing must climb.

acetaminophen 500mg

Skip it

A deep review moat (35,444 avg reviews) — this niche doesn't clear our bar today.

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Conversion

Incredible12.6%

search→purchase rate — share of searches ending in a sale

Price range

Good$3.26–$30.70

cheapest to priciest tracked listing — scored on the share inside $15–$100

Avg price

Good$12.65

avg listing price — sweet spot $15–$100

Market size

Okay$260K

$260K/yr · 163K searches

Competition

Bad71%

top-5 click share — a locked-up shelf

Growth

Bad-8.0%

90-day search growth — must beat 0% to launch

Brand share

Bad93%

top-5 brand share — brand-locked demand

Quality gap

Bad4.8★

avg incumbent rating — lower means beatable quality

Review moat

Bad35,444.25

avg incumbent reviews — the moat a new listing must climb

According to Flapen's Amazon United States niche tracking, acetaminophen 500mg is a $260K/yr Amazon United States market (163K searches/yr). The top 5 brands hold 93% of demand. Demand peaks in Sep–Oct. Verdict: Skip it — 43/100.

Data updated Jul 11, 2026 · scored weekly · How we score niches

acetaminophen 500mg market data

Units sold / yr: 20K–25K; avg 1,250–1,500/product
Revenue / yr: $253K–$316K; units × avg price
Conversion rate: 12.6%
Avg BSR: #81
Page quality: 0%
Prime: 88%
Sponsored: 100%
Out of stock: 0.0%
Avg brand age: 98 months
Avg seller age: 156 days

Competition & brand share

The top 5 products capture 71% of clicks — a locked-up shelf that new listings rarely crack.

Brands

8 rising

Sellers

Top-5 brand share

93%

Top 20: 100%

Top-5 click share

71%

Top 20: 100%

Open market

Amazon Basic Care61%
Belmora paracetamol18%
HealthA2Z5%
Tylenol5%
Generic4%
GoodMeds3%
Open — no brand owns it (2 brands, 4%)

Demand & seasonality

Weekly Amazon search volume, last 104 weeks — -8.0% search growth over the last 90 days.

Peak months: Sep, Oct · busiest ÷ quietest = 2.6×

Open Trend

Top acetaminophen 500mg search terms

paracetamol 500mg tablets for adults68K/yr -26.7%6.2% conv.
generic tylenol17K/yr +6.9%19.0% conv.
generic tylenol extra strength 500mg6K/yr +130.8%21.3% conv.
paracetamol 1000mg19K/yr -25.9%3.4% conv.
amazon acetaminophen 500mg extra strength10K/yr +13.8%22.2% conv.
kirkland acetaminophen 500mg extra strength7K/yr +43.2%6.0% conv.
acetomenaphen extra strength 500mg generic amazon 500 caplets9K/yr -35.5%23.9% conv.
equate acetaminophen 500mg extra strength6K/yr +1.4%9.4% conv.
equate pain reliever 500mg6K/yr -14.0%8.5% conv.
equate pain reliever5K/yr +27.4%4.7% conv.

All search terms

Top acetaminophen 500mg products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 16 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever/Fever Reducer 500 Count

Amazon Basic Care$8.504.8★90,285 rev

Belmora Paracetamol Acetaminophen 325mg 20 Softgels for Pain Relief Liquid Filled Capsules for Rapid Release Fever Reducer for Adults Extra Strength

Belmora paracetamol$8.164.6★788 rev

Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg 200 Count

Amazon Basic Care$5.334.8★90,285 rev

Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever and Fever Reducer for Headache Backache Arthritis Pain Menstrual Cramps 1000 Count (Packaging may vary)

Amazon Basic Care$14.294.8★90,285 rev

Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever/Fever Reducer 100 Count

Amazon Basic Care$3.264.8★90,285 rev

Newest

by launch date

GoodMeds Compare to Extra Strength Tylenol | Acetaminophen 500mg Extra Strength Pain Reliever & Fever Reducer | Headache Muscle Aches Back Pain Cold & Flu Relief 500 Count

GoodMeds$9.81403 rev

8mo ago

Extra Strength Acetaminophen 500mg Gelcaps - 225 Count (Pack of 1)

Generic$23.14162 rev

1y ago

Acetaminophen 500mg Extra Strength Rapid Release 400 Gelcaps

Generic$30.70129 rev

1y ago

Belmora Paracetamol Acetaminophen 325mg 20 Softgels for Pain Relief Liquid Filled Capsules for Rapid Release Fever Reducer for Adults Extra Strength

Belmora paracetamol$8.16788 rev

3y ago

Amazon Basic Care Extra Strength Acetaminophen Caplets 500 mg Pain Reliever and Fever Reducer Gentle on Stomach For Arthritis Pain Backache Pain and More 50 Packets of 2 Capsules Each 100 Count

Amazon Basic Care$8.082,310 rev

4y ago

What buyers say about acetaminophen 500mg

What buyers praise and complain about, mined from review topics.

What buyers love

Value For Money39%

“they are affordable”

Quality-Overall13%

“Definitely reliable and affordable—highly recommended”

Advertised Vs Actual Product9%

“AS ADVERTISED”

Efficiency9%

“Works Well”

Dosage4%

“effective as the higher dose pills”

Ease Of Use3%

“Easy open”

Ease Of Chewing/Swallowing3%

“Easily swallowed”

Ingredients-Overall2%

“Great acetaminophen product for great price”

Joint Pain2%

“My On Going Joint Pain 😩 Works Well For Me”

Size-Overall2%

“Great size”

What buyers complain about

Functionality-Overall8%

“the effectiveness just isnt there”

Ease Of Chewing/Swallowing7%

“Dissolves before swallowing”

Size-Overall7%

“The bottle is wildly large”

Dosage6%

“The dosage is not on the bottle”

Pain Relief-Overall6%

“Doesnt help with pain at all”

Value For Money5%

“cheaper”

Taste-Overall5%

“leave a bitter taste”

Ease Of Use4%

“Cannot use”

Quality-Overall3%

“No quality control”

Strength2%

“Not strong at all”

Common questions

Is acetaminophen 500mg profitable to sell on Amazon United States?: The niche generates $260K/yr across 16 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is -8.0%. Flapen's verdict: Skip it (43/100).
How competitive is the acetaminophen 500mg niche?: 8 brands and 75 sellers compete. The top 5 products take 71% of clicks and top 5 brands hold 93% of demand.
What do buyers complain about in acetaminophen 500mg?: Top complaints mined from reviews: Functionality-Overall, Ease Of Chewing/Swallowing, Size-Overall. The return rate is 0.0%.
When does demand for acetaminophen 500mg peak?: Demand peaks in Sep–Oct; the busiest month runs 2.6× the quietest.
What does it cost to enter the acetaminophen 500mg niche?: Listings span $3.26–$30.70; the average listing price is $12.65 (sweet spot $15–$100). The average incumbent carries 35,444 reviews — the moat a new listing must climb.