Is acetaminophen 325mg tablets profitable to sell on Amazon United States?

The niche generates $452K/yr across 5 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is -4.0%. Flapen's verdict: Skip it (36/100).

How competitive is the acetaminophen 325mg tablets niche?

5 brands and 60 sellers compete. The top 5 products take 100% of clicks and top 5 brands hold 100% of demand.

What do buyers complain about in acetaminophen 325mg tablets?

Top complaints mined from reviews: Dosage, Pain Relief-Overall, Ease Of Chewing/Swallowing. The return rate is 0.0%.

When does demand for acetaminophen 325mg tablets peak?

Demand is steady year-round — the busiest month runs 1.5× the quietest.

What does it cost to enter the acetaminophen 325mg tablets niche?

Listings span $3.26–$14.53; the average listing price is $7.94 (sweet spot $15–$100). The average incumbent carries 18,876 reviews — the moat a new listing must climb.

acetaminophen 325mg tablets

Skip it

A concentrated shelf (top 5 take 100% of clicks) — this niche doesn't clear our bar today.

Conversion

Incredible23.5%

search→purchase rate — share of searches ending in a sale

Returns

Incredible0.0%

return rate — above 5% kills the launch gate

Market size

Good$452K

$452K/yr · 242K searches

Growth

Bad-4.0%

90-day search growth — must beat 0% to launch

Avg price

Bad$7.94

avg listing price — sweet spot $15–$100

Review moat

Bad18,876.2

avg incumbent reviews — the moat a new listing must climb

Quality gap

Bad4.8★

avg incumbent rating — lower means beatable quality

Competition

Bad100%

top-5 click share — a locked-up shelf

Brand share

Bad100%

top-5 brand share — brand-locked demand

Price range

Bad$3.26–$14.53

cheapest to priciest tracked listing — scored on the share inside $15–$100

According to Flapen's Amazon United States niche tracking, acetaminophen 325mg tablets is a $452K/yr Amazon United States market (242K searches/yr). The top 5 brands hold 100% of demand. Verdict: Skip it — 36/100.

Data updated Jul 11, 2026 · scored weekly · How we score niches

acetaminophen 325mg tablets market data

Units sold / yr: 60K–80K; avg 8,000–10,000/product
Revenue / yr: $476K–$635K; units × avg price
Conversion rate: 23.5%
Avg BSR: #65
Page quality: 0%
Prime: 100%
Sponsored: 60%
Out of stock: 0.0%
Avg brand age: 80 months
Avg seller age: 159 days

Competition & brand share

The top 5 products capture 100% of clicks — a locked-up shelf that new listings rarely crack.

Brands

5 rising

Sellers

Top-5 brand share

100%

Top 20: 100%

Top-5 click share

100%

Top 20: 100%

Open market

Tylenol65%
TIME-CAP LABS, INC.20%
GeriCare6%
GoodSense5%
Amazon Basic Care5%

Demand & seasonality

Weekly Amazon search volume, last 104 weeks — -4.0% search growth over the last 90 days.

No pronounced peak months · busiest ÷ quietest = 1.5×

Open Trend

Top acetaminophen 325mg tablets search terms

acetaminophen 325mg57K/yr -3.8%15.5% conv.
tylenol regular strength32K/yr -3.9%25.6% conv.
tylenol 325mg tablets30K/yr -10.4%27.2% conv.
tylenol 325 mg20K/yr -2.1%24.1% conv.
tylenol 32513K/yr -0.0%19.9% conv.
regular strength tylenol13K/yr -6.7%23.4% conv.
acetaminophen 32510K/yr +30.9%12.4% conv.
tylenol regular strength 325mg10K/yr -14.7%23.7% conv.
325 mg tylenol6K/yr -7.6%22.9% conv.
acetaminophen 325mg tablets12K/yr -21.5%12.1% conv.

All search terms

Top acetaminophen 325mg tablets products on Amazon

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 5 tracked products in this niche — three views at once, no toggling.

Top sellers

by 90-day click share

Tylenol Regular Strength Tablets with 325 mg of Acetaminophen Fever Reducer & Pain Reliever for Headache Backache Muscle Aches Joint Pain & Menstrual Cramps 100 ct

Tylenol$6.884.8★2,602 rev

TIME-Cap Labs 1000 Tablets Regular Strength Acetaminophen 325mg - Pain Reliever & Fever Reducer for Adults Helps with Headaches Backaches Muscle Pain Toothaches Arthritis & Menstrual Cramps

TIME-CAP LABS, INC.$14.534.8★1,088 rev

GeriCare Regular Strength Acetaminophen Pain Relief Fever Reducer Tablets Strength 325mg Tablet | Joint Muscle Arthritis Back Pain Relief 200 Count (Pack of 1)

GeriCare$8.904.7★295 rev

Pain Relief Acetaminophen Tablets 325 mg Regular Strength Pain Reliever and Fever Reducer

GoodSense$6.114.7★111 rev

Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever/Fever Reducer 100 Count

Amazon Basic Care$3.264.8★90,285 rev

Newest

by launch date

Pain Relief Acetaminophen Tablets 325 mg Regular Strength Pain Reliever and Fever Reducer

GoodSense$6.11111 rev

11mo ago

Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever/Fever Reducer 100 Count

Amazon Basic Care$3.2690,285 rev

4y ago

TIME-Cap Labs 1000 Tablets Regular Strength Acetaminophen 325mg - Pain Reliever & Fever Reducer for Adults Helps with Headaches Backaches Muscle Pain Toothaches Arthritis & Menstrual Cramps

TIME-CAP LABS, INC.$14.531,088 rev

5y ago

GeriCare Regular Strength Acetaminophen Pain Relief Fever Reducer Tablets Strength 325mg Tablet | Joint Muscle Arthritis Back Pain Relief 200 Count (Pack of 1)

GeriCare$8.90295 rev

6y ago

Tylenol Regular Strength Tablets with 325 mg of Acetaminophen Fever Reducer & Pain Reliever for Headache Backache Muscle Aches Joint Pain & Menstrual Cramps 100 ct

Tylenol$6.882,602 rev

18y ago

What buyers say about acetaminophen 325mg tablets

What buyers praise and complain about, mined from review topics.

What buyers love

Value For Money34%

“Reasonable price”

Advertised Vs Actual Product13%

“As advertised”

Quality-Overall13%

“Excellent quality medication”

Dosage12%

“Same as every other of same formula and dosage”

Efficiency8%

“Effective”

Ease Of Use2%

“Easy, quick buy”

Ease Of Chewing/Swallowing2%

“easy to swallow”

Strength2%

“Effective”

Joint Pain2%

“I can't use ibuprofen because of kidney disease and this works perfectly for minor aches and pains”

Safety Standards2%

“The safety cap is good to keep young children opening the bottle”

What buyers complain about

Dosage19%

“Smaller dose”

Pain Relief-Overall15%

“I had a muscle ache - now it's gone - was it the pills or time”

Ease Of Chewing/Swallowing14%

“especially for people who already have difficulty swallowing pills in general”

Taste-Overall6%

“they have an awful taste”

Size-Overall5%

“The tablets are on the larger side”

Functionality-Overall4%

“doesnt seem work as well as name brand tylenol for my migraines”

Quality-Overall4%

“Quality wasnt to great”

Washability2%

“There is so much that I have to wash my hands after using because it makes a huge mess”

De-Grease2%

“the inside of the cap had a greasy”

Ease Of Cleaning2%

“Dirty inside”

Top return reasons

Value For Money100%

Common questions

Is acetaminophen 325mg tablets profitable to sell on Amazon United States?: The niche generates $452K/yr across 5 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is -4.0%. Flapen's verdict: Skip it (36/100).
How competitive is the acetaminophen 325mg tablets niche?: 5 brands and 60 sellers compete. The top 5 products take 100% of clicks and top 5 brands hold 100% of demand.
What do buyers complain about in acetaminophen 325mg tablets?: Top complaints mined from reviews: Dosage, Pain Relief-Overall, Ease Of Chewing/Swallowing. The return rate is 0.0%.
When does demand for acetaminophen 325mg tablets peak?: Demand is steady year-round — the busiest month runs 1.5× the quietest.
What does it cost to enter the acetaminophen 325mg tablets niche?: Listings span $3.26–$14.53; the average listing price is $7.94 (sweet spot $15–$100). The average incumbent carries 18,876 reviews — the moat a new listing must climb.