Two decisions, not one
Sellers often collapse selling on Amazon into a single question. It is two. The first is your fulfillment model — who stores your inventory and ships each order. The second is your seller model — what you sell and where the product comes from. They are independent: any seller model can run on either fulfillment model.
Each choice buys you something and costs you something, and the costs sit in different places.
Choosing a fulfillment model
Fulfillment is a choice between letting Amazon handle storage and shipping (fulfilled by Amazon — FBA) or doing it yourself (fulfilled by the merchant). Letting Amazon fulfill buys reach: your offers become eligible for the fast-shipping badge many buyers filter for, which lifts conversion. It costs you fees on storage and each unit shipped, and hands day-to-day control to a third party.
Fulfilling orders yourself buys control — and margin when your own storage and shipping cost less than the fees they replace. You set the packaging and hold the inventory. It costs you conversion, because self-fulfilled offers rarely carry the fast-shipping badge buyers trust, and every late shipment lands on your own record. Self-fulfillment can be acceptable for oversized, slow-moving, or highly variable products where storage fees would punish you. For most standard-sized private-label products, FBA usually wins on reach.
Choosing a seller model
Your seller model determines what you list and how much of the product you actually control.