---
title: "Fish-zole (metronidazole 250mg) — $104K/yr Amazon US Niche (2026) - Flapen"
canonical_url: "https://flapen.com/research/us/pet-supplies/fish-zole-metronidazole-250mg"
last_updated: "2026-07-21T19:19:18.442Z"
locale: en
meta:
description: "Niche score 44/100 · $104K/yr market · 81K searches/yr · $19.82 avg price. Doesn't clear our bar today. Data updated Jul 2026."
"og:description": "Niche score 44/100 · $104K/yr market · 81K searches/yr · $19.82 avg price. Doesn't clear our bar today. Data updated Jul 2026."
"og:title": "Fish-zole (metronidazole 250mg) — $104K/yr Amazon US Niche (2026) - Flapen"
---
# **fish-zole (metronidazole 250mg)**
**Skip it**
Brand-locked demand (top 5 brands take 95% of clicks) — this niche doesn't clear our bar today.
Market size 26Growth 35Conversion 70Competition 29Returns 91Price range 85Avg price 87Brand share 12Review moat 25Quality gap 33
**Returns**
**Great****1.2%**
return rate — above 6% kills the launch gate
**Avg price**
**Great****$19.82**
avg listing price — sweet spot $15–$100
**Price range**
**Great****$7.23–$72.26**
cheapest to priciest tracked listing — scored on the share inside $15–$100
**Conversion**
**Good****6.4%**
search→purchase rate — share of searches ending in a sale
**Growth**
**Okay****+8.1%**
90-day search growth — must beat 0% to launch
**Quality gap**
**Okay****4.5★**
avg incumbent rating — lower means beatable quality
**Competition**
**Okay****68%**
top-5 click share — leaders hold, buyers still browse
**Market size**
**Okay****$104K**
$104K/yr · 81K searches
**Review moat**
**Bad****4,201.47**
avg incumbent reviews — the moat a new listing must climb
**Brand share**
**Bad****95%**
top-5 brand share — brand-locked demand
According to Flapen's Amazon United States niche tracking, fish-zole (metronidazole 250mg) is a $104K/yr Amazon United States market (81K searches/yr). The top 5 brands hold 95% of demand. Verdict: Skip it — 44/100.
Data updated Jul 17, 2026 · scored weekly · [~~How we score niches ~~](https://flapen.com/research/methodology)
## **fish-zole (metronidazole 250mg) market data**
- **Units sold / yr**
- **10K–13K**
- avg 250–500/product
- **Revenue / yr**
- **$198K–$248K**
- units × avg price
- **Launch success**
- **—**
- 0 of 0 new (360d)
- **Conversion rate**
- **6.4%**
- **Avg BSR**
- **#79**
- **Page quality**
- **0%**
- **Prime**
- **95%**
- **Sponsored**
- **68%**
- **Out of stock**
- **1.3%**
- **Avg brand age**
- **100 months**
- **Avg seller age**
- **165 days**
## **Competition & brand share**
The top 5 products take 68% of clicks — established leaders, but buyers still shop beyond them.
**Brands**
**9 **—flat
**Sellers**
**66**
**Top-5 brand share**
**95%**
Top 20: 100%
**Top-5 click share**
**68%**
Top 20: 100%
**Open market**
**3%**
- API58% - Seachem18% - ีUSA8% - Fritz Aquatics8% - Hikari3% - MICROBE-LIFT2% - Open — no brand owns it (3 brands, 3%)
## **Demand & seasonality**
Weekly Amazon search volume, last 67 weeks — +8.1% search growth over the last 90 days.
2K2KSpike '26 seasonAprMayJunJulAugSepOctNovDecJanFebMarAprMayJun
No pronounced peak months · busiest ÷ quietest = 1.4×
[**Open Trend **](https://flapen.com/research/us/pet-supplies/fish-zole-metronidazole-250mg/trend)
## **Top fish-zole (metronidazole 250mg) search terms**
- **api general cure**33K/yr+25.7%3.7% conv. - **metronidazole for fish**15K/yr-16.0%7.2% conv. - **general cure fish medication**11K/yr+3.1%3.1% conv. - **general cure**7K/yr-2.9%2.7% conv. - **fish-zole (metronidazole 250mg)**7K/yr-17.2%1.6% conv. - **api general cure freshwater**5K/yr+36.1%3.9% conv. - **fish zole**2K/yr+22.2%2.4% conv. [**All search terms **](https://flapen.com/research/us/pet-supplies/fish-zole-metronidazole-250mg/search-terms)
## **Top fish-zole (metronidazole 250mg) products on Amazon**
Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.
0%10%$10K20%$21K30%$31K40%$41K101001K10K100K Reviews — right = deep review moatMarket share (90d) ≈ est. sales
Beatable (≤4.3★) Contested Strong incumbent (>4.7★)
All 19 tracked products in this niche — three views at once, no toggling.
### **Top sellers**
by 90-day click share
[1**API General Cure Powder Packets 10 Count 6 Pack**API**$72.26**4.7★149 rev](https://www.amazon.com/dp/B073PCX96L) [2**API FIN & BODY CURE Freshwater Fish Powder Medication 10-Count Box**API**$16.11**4.4★3,763 rev](https://www.amazon.com/dp/B06XDFJ5XN) [3**Seachem Metronidazole 5 g(0.18 oz)**Seachem**$9.86**4.5★1,034 rev](https://www.amazon.com/dp/B0002A5X8W) [4**Seachem MetroPlex Metronidazole Parasite Bacteria SALTWATER FRESHWATER Aquarium**ีUSA**$11.62**4.6★834 rev](https://www.amazon.com/dp/B01M5LEDRA) [5**Fritz Aquatics ParaCleanse Provides Fast Relief from Parasitic Diseases (20-Count)**Fritz Aquatics**$22.41**4.6★376 rev](https://www.amazon.com/dp/B09F4HV8HH)
**~~View all top sellers →~~**
### **Newest**
by launch date
[**Metroplex METRONlDAZOLE Focus Kanaplex Paraguard Neoplex Sulfaplex Polyguard Garlic Guard Saltwater Freshwater Aquarium lnfection ANTlBlOTlC (Metroplex + Kanaplex + Focus)**Generic**$29.52**66 rev2y ago](https://www.amazon.com/dp/B0CPVBBYS5) [**API Liquid Super ICK Cure Freshwater and Saltwater Fish Medication 16-Ounce Bottle**API**$19.97**11,785 rev4y ago](https://www.amazon.com/dp/B09FFQBKSX) [**Fritz Aquatics ParaCleanse Provides Fast Relief from Parasitic Diseases (20-Count)**Fritz Aquatics**$22.41**376 rev4y ago](https://www.amazon.com/dp/B09F4HV8HH) [**Absolute Wormer - Freshwater and Saltwater Fish Powder Medication. with parasites and Flukes. (5G - Treats 600 GALLONS)**Absolute Wormer**$23.76**434 rev6y ago](https://www.amazon.com/dp/B085Z1QF2Y) [**Seachem SC 10g POLYGUARD 0.4oz**Seachem**$9.98**395 rev6y ago](https://www.amazon.com/dp/B007R5303U)
**~~View all new products →~~**
### **Trending**
90-day click momentum
[**API General Cure Powder Packets 10 Count 6 Pack**API**$72.26**4.7★**▲ 116%**](https://www.amazon.com/dp/B073PCX96L) [**Seachem ParaGuard 500 mL / 16.9 fl. oz. - 603**Seachem**$17.06**4.7★**▲ 60%**](https://www.amazon.com/dp/B002DWTIU6) [**Seachem SC 10g POLYGUARD 0.4oz**Seachem**$9.98**4.7★**▲ 59%**](https://www.amazon.com/dp/B007R5303U) [**Fritz Aquatics ParaCleanse Provides Fast Relief from Parasitic Diseases (20-Count)**Fritz Aquatics**$22.41**4.6★**▲ 57%**](https://www.amazon.com/dp/B09F4HV8HH) [**API Liquid Super ICK Cure Freshwater and Saltwater Fish Medication 16-Ounce Bottle**API**$19.97**4.5★**▲ 25%**](https://www.amazon.com/dp/B09FFQBKSX)
**~~View all trending →~~**
## **What buyers say about fish-zole (metronidazole 250mg)**
What buyers praise and complain about, mined from review topics.
### **What buyers love **
**Quality-Overall**17%
*“Fish med great”*
**Ease Of Use**14%
*“Easy to use”*
**Value For Money**14%
*“Price is affordable”*
**Advertised Vs Actual Product**12%
*“Worked as advertised”*
**Instructions/User Manual/Troubleshooting**6%
*“the instructions are clear enough”*
**Ease Of Cleaning**4%
*“Clean sweep of flukes”*
**Strength**4%
*“Strong”*
**Time Taken**4%
*“Helped quickly”*
**Smell**3%
*“I love the smell”*
**Color**3%
*“My glofish is still bright pink”*
### **What buyers complain about **
**Durability**11%
*“died very quickly after that”*
**Value For Money**11%
*“It is definitely expensive for the small amount”*
**Contamination**8%
*“Caused fish d**th”*
**Functionality-Overall**7%
*“Unfortunately, it did not work in my case”*
**Color**6%
*“Blue blue blue stained everywhere”*
**Smell**6%
*“This thing smells like rotten eggs”*
**Breathability**5%
*“He's having trouble breathing”*
**Leak-Proof**5%
*“the product inside had leaked out some due to a loose cap and no seal”*
**Allergies**5%
*“If your fish seem itchy, or irritated and you notice a lot of flashing or rubbing”*
**Ease Of Use**4%
*“Never easy to use”*
### **Top return reasons **
**Functionality-Overall**31%
**Advertised Vs Actual Product**17%
**Leak-Proof**12%
**Value For Money**12%
**Size-Overall**4%
**Product Condition**4%
**Defective Material/Parts**4%
**Durability**2%
**Compatibility-Overall**2%
**Contamination**1%
## **Common questions**
- **Is fish-zole (metronidazole 250mg) profitable to sell on Amazon United States?**
- The niche generates $104K/yr across 19 tracked products. 90-day search growth is +8.1%. Flapen's verdict: Skip it (44/100).
- **How competitive is the fish-zole (metronidazole 250mg) niche?**
- 9 brands and 66 sellers compete. The top 5 products take 68% of clicks and top 5 brands hold 95% of demand.
- **What do buyers complain about in fish-zole (metronidazole 250mg)?**
- Top complaints mined from reviews: Durability, Value For Money, Contamination. The return rate is 1.2%.
- **When does demand for fish-zole (metronidazole 250mg) peak?**
- Demand is steady year-round — the busiest month runs 1.4× the quietest.
- **What does it cost to enter the fish-zole (metronidazole 250mg) niche?**
- Listings span $7.23–$72.26; the average listing price is $19.82 (sweet spot $15–$100). The average incumbent carries 4,201 reviews — the moat a new listing must climb.
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