---
title: "Tributyrin — $415K/yr Amazon US Niche (2026) - Flapen"
canonical_url: "https://flapen.com/research/us/health-household/tributyrin"
last_updated: "2026-08-06T16:51:53.272Z"
locale: en
meta:
  description: "Niche score 65/100 · $415K/yr market. A failed launch gate (market size, growth, or returns) keeps it on the watch list. Data updated Jul 2026."
  "og:description": "Niche score 65/100 · $415K/yr market. A failed launch gate (market size, growth, or returns) keeps it on the watch list. Data updated Jul 2026."
  "og:title": "Tributyrin — $415K/yr Amazon US Niche (2026) - Flapen"
---

# **tributyrin**

**Worth a look**

Shows low returns (0.0%), but a failed launch gate (market size, growth, or returns) keeps it on the watch list.

Market size 56Growth 54Conversion 84Competition 30Returns 100Price range 94Avg price 95Brand share 54Review moat 90Quality gap 63

**Returns**

**Incredible****0.0%**

return rate — above 5% kills the launch gate

**Avg price**

**Incredible****$31.73**

avg listing price — sweet spot $15–$100

**Price range**

**Great****$14.58–$80.24**

cheapest to priciest tracked listing — scored on the share inside $15–$100

**Review moat**

**Great****200.65**

avg incumbent reviews — the moat a new listing must climb

**Conversion**

**Great****9.2%**

search→purchase rate — share of searches ending in a sale

**Quality gap**

**Good****4.4★**

avg incumbent rating — lower means beatable quality

**Market size**

**Good****$415K**

$415K/yr · 143K searches

**Growth**

**Good****+25.7%**

90-day search growth — must beat 0% to launch

**Brand share**

**Good****73%**

top-5 brand share — brands hold most of the demand

**Competition**

**Okay****67%**

top-5 click share — leaders hold, buyers still browse

**Signals**[** Low Review Barrier**](https://flapen.com/research/niches?market=us&signal=low_review_barrier "Top brand's reviews < 500")

According to Flapen's Amazon United States niche tracking, tributyrin is a $415K/yr Amazon United States market (143K searches/yr). The top 5 brands hold 73% of demand. Demand peaks in May–Jun–Jul. Verdict: Worth a look — 65/100.

Data updated Jul 25, 2026 · scored weekly · [~~How we score niches ~~](https://flapen.com/research/methodology)

## **tributyrin market data**

<dl>

<dt>**Units sold / yr**</dt><dd>**10K–13K**</dd><dd>avg 500–750/product</dd>

<dt>**Revenue / yr**</dt><dd>**$317K–$397K**</dd><dd>units × avg price</dd>

<dt>**Conversion rate**</dt><dd>**9.2%**</dd>

<dt>**Avg BSR**</dt><dd>**#3,160**</dd>

<dt>**Page quality**</dt><dd>**0%**</dd>

<dt>**Prime**</dt><dd>**100%**</dd>

<dt>**Sponsored**</dt><dd>**82%**</dd>

<dt>**Out of stock**</dt><dd>**0.0%**</dd>

<dt>**Avg brand age**</dt><dd>**78 months**</dd>

<dt>**Avg seller age**</dt><dd>**150 days**</dd>

</dl>

## **Competition & brand share**

The top 5 products take 67% of clicks — established leaders, but buyers still shop beyond them.

**Brands**

**15 **▼falling

**Sellers**

**26**

**Top-5 brand share**

**73%**

Top 20: 100%

**Top-5 click share**

**67%**

Top 20: 100%

**Open market**

**22%**

- Peak Performance23% - Designs for Health21% - Quorinthiumax11% - Healthy Gut11% - ForestVibe7% - Doctor's BEST5%

## **Demand & seasonality**

Weekly Amazon search volume, last 102 weeks — +25.7% search growth over the last 90 days.

4K3KSpike '24Spike '25Prime Day '25Spike '26 seasonDecMarJunAugNovMarMay

Peak months: May, Jun, Jul · busiest ÷ quietest = 1.9×

[**Open Trend **](https://flapen.com/research/us/health-household/tributyrin/trend)

## **Top tributyrin search terms**

- **tributyrin**76K/yr+39.2%6.2% conv. - **tributyrin supplement**25K/yr+9.4%7.1% conv. - **corebiome tributyrin**7K/yr+35.5%7.0% conv. - **tributyrate**6K/yr+11.3%5.5% conv. - **corebiome**7K/yr-5.1%3.6% conv. - **tributyrin-x**7K/yr+18.5%8.7% conv. - **tri butyrin supreme**3K/yr+57.4%22.8% conv. - **tributyrate for constipation**3K/yr-38.8%5.8% conv. - **butyrin**3K/yr+97.6%0.8% conv. - **tri-butyrin supreme**3K/yr+24.5%23.6% conv. [**All search terms **](https://flapen.com/research/us/health-household/tributyrin/search-terms)

## **Top tributyrin products on Amazon**

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

0%10%$42K20%$83K30%$125K40%$166K101001K Reviews — right = deep review moatMarket share (90d) ≈ est. sales

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 17 tracked products in this niche — three views at once, no toggling.

### **Top sellers**

by 90-day click share

[1![CoreBiome Tributyrin Postbiotic Supplement Clinically Tested for Gut Health. More Effective Than Sodium Butyrate Capsules. High Bioavailability Post Biotics for Digestive Leaky Gut Colon Microbiome](https://m.media-amazon.com/images/I/51hiUxuif1L.jpg)**CoreBiome Tributyrin Postbiotic Supplement Clinically Tested for Gut Health. More Effective Than Sodium Butyrate Capsules. High Bioavailability Post Biotics for Digestive Leaky Gut Colon Microbiome**Peak Performance**$35.16**4.4★308 rev](https://www.amazon.com/dp/B0B194KJ92) [2![Designs for Health Tri-Butyrin Supreme - 3-in-1 Butyric Acid (Butyrate) Postbiotics for Gut Health & Gut Permeability Support - Tributyrin Supplement with Odor-Minimizing Innovation (60 Softgels)](https://m.media-amazon.com/images/I/41dHEqHYBUL.jpg)**Designs for Health Tri-Butyrin Supreme - 3-in-1 Butyric Acid (Butyrate) Postbiotics for Gut Health & Gut Permeability Support - Tributyrin Supplement with Odor-Minimizing Innovation (60 Softgels)**Designs for Health**$51.71**4.6★439 rev](https://www.amazon.com/dp/B08D9NMNNQ) [3![Tributyrin Supplement for Gut & Immune 800mg | High Bioavailability with Microencapsulated Probiotics & Prebiotics - Advanced Liquid-Filled Tributyrin Complex Gluten Free 90 Capsules](https://m.media-amazon.com/images/I/41uAiaAvp9L.jpg)**Tributyrin Supplement for Gut & Immune 800mg | High Bioavailability with Microencapsulated Probiotics & Prebiotics - Advanced Liquid-Filled Tributyrin Complex Gluten Free 90 Capsules**Quorinthiumax**$27.22**4.3★377 rev](https://www.amazon.com/dp/B0DPMQPC4H) [4![Healthy Gut Tributyrin-X | Most Bioavailable Butyrate Supplement for Gut Health & Leaky Gut Support | 99% Pure w/Zero Odor | 90 Softgels](https://m.media-amazon.com/images/I/31lTOdNOyRL.jpg)**Healthy Gut Tributyrin-X | Most Bioavailable Butyrate Supplement for Gut Health & Leaky Gut Support | 99% Pure w/Zero Odor | 90 Softgels**Healthy Gut**$80.24**4.4★248 rev](https://www.amazon.com/dp/B09H68YHT2) [5![Tributyrin Supplement 550mg Advanced Butyrate Form for Gut Health 60% Standardized More Effective Delivery Than Sodium Butyrate 90 Capsules Non-GMO & Gluten Free Postbiotic Supplement](https://m.media-amazon.com/images/I/41h7VVOpHGL.jpg)**Tributyrin Supplement 550mg Advanced Butyrate Form for Gut Health 60% Standardized More Effective Delivery Than Sodium Butyrate 90 Capsules Non-GMO & Gluten Free Postbiotic Supplement**ForestVibe**$21.86**4.6★54 rev](https://www.amazon.com/dp/B0G64ZWGLF)

**~~View all top sellers →~~**

### **Newest**

by launch date

[![Sports Research Tribiotic 3-in-1 Pre Post & Probiotic 30 Liquid Caps](https://m.media-amazon.com/images/I/41uuQRXWD3L.jpg)**Sports Research Tribiotic 3-in-1 Pre Post & Probiotic 30 Liquid Caps**Sports Research**$33.55**27 rev3mo ago](https://www.amazon.com/dp/B0GWS54QCZ) [![VitalOne Tributyrin 250 mg Supplement | Single Ingredient Butyrate Prodrug | Gut & Digestive Support | Clean Label | 1 Capsule Daily | 90 Capsules](https://m.media-amazon.com/images/I/416jyGWg7IL.jpg)**VitalOne Tributyrin 250 mg Supplement | Single Ingredient Butyrate Prodrug | Gut & Digestive Support | Clean Label | 1 Capsule Daily | 90 Capsules**VitalOne**$18.16**24 rev5mo ago](https://www.amazon.com/dp/B0GNTM9FKV) [![YOUBYNATURE Tributyrin 250mg | Single Ingredient Tributyrin Supplement | Vegan | Gluten Free | Unflavored Veggie Capsules | 1 Capsule Daily | 90 Capsules | 90-Day Supply](https://m.media-amazon.com/images/I/41SHi0GpMzL.jpg)**YOUBYNATURE Tributyrin 250mg | Single Ingredient Tributyrin Supplement | Vegan | Gluten Free | Unflavored Veggie Capsules | 1 Capsule Daily | 90 Capsules | 90-Day Supply**YOUBYNATURE**$16.49**24 rev5mo ago](https://www.amazon.com/dp/B0GNPKSDHN) [![Tributyrin Supplement 550mg Advanced Butyrate Form for Gut Health 60% Standardized More Effective Delivery Than Sodium Butyrate 90 Capsules Non-GMO & Gluten Free Postbiotic Supplement](https://m.media-amazon.com/images/I/41h7VVOpHGL.jpg)**Tributyrin Supplement 550mg Advanced Butyrate Form for Gut Health 60% Standardized More Effective Delivery Than Sodium Butyrate 90 Capsules Non-GMO & Gluten Free Postbiotic Supplement**ForestVibe**$21.86**54 rev7mo ago](https://www.amazon.com/dp/B0G64ZWGLF) [![Immortal Herbs Tributyrin Supplement 800mg Advanced Butyrate Form 55% Standardized More Effective Delivery Than Sodium Butyrate 120 Capsules Non-GMO & Gluten Free Postbiotic Supplement](https://m.media-amazon.com/images/I/41dAlBAPdLL.jpg)**Immortal Herbs Tributyrin Supplement 800mg Advanced Butyrate Form 55% Standardized More Effective Delivery Than Sodium Butyrate 120 Capsules Non-GMO & Gluten Free Postbiotic Supplement**Immortal Herbs**$23.92**51 rev7mo ago](https://www.amazon.com/dp/B0G66LXW3J)

**~~View all new products →~~**

### **Trending**

90-day click momentum

[![VitalOne Tributyrin 250 mg Supplement | Single Ingredient Butyrate Prodrug | Gut & Digestive Support | Clean Label | 1 Capsule Daily | 90 Capsules](https://m.media-amazon.com/images/I/416jyGWg7IL.jpg)**VitalOne Tributyrin 250 mg Supplement | Single Ingredient Butyrate Prodrug | Gut & Digestive Support | Clean Label | 1 Capsule Daily | 90 Capsules**VitalOne**$18.16**4.4★**▲ 193%**](https://www.amazon.com/dp/B0GNTM9FKV) [![Sports Research Tribiotic 3-in-1 Pre Post & Probiotic 30 Liquid Caps](https://m.media-amazon.com/images/I/41uuQRXWD3L.jpg)**Sports Research Tribiotic 3-in-1 Pre Post & Probiotic 30 Liquid Caps**Sports Research**$33.55**4.5★**▲ 191%**](https://www.amazon.com/dp/B0GWS54QCZ) [![YOUBYNATURE Tributyrin 250mg | Single Ingredient Tributyrin Supplement | Vegan | Gluten Free | Unflavored Veggie Capsules | 1 Capsule Daily | 90 Capsules | 90-Day Supply](https://m.media-amazon.com/images/I/41SHi0GpMzL.jpg)**YOUBYNATURE Tributyrin 250mg | Single Ingredient Tributyrin Supplement | Vegan | Gluten Free | Unflavored Veggie Capsules | 1 Capsule Daily | 90 Capsules | 90-Day Supply**YOUBYNATURE**$16.49**4.4★**▲ 187%**](https://www.amazon.com/dp/B0GNPKSDHN) [![Tributyrin Supplement 550mg Advanced Butyrate Form for Gut Health 60% Standardized More Effective Delivery Than Sodium Butyrate 90 Capsules Non-GMO & Gluten Free Postbiotic Supplement](https://m.media-amazon.com/images/I/41h7VVOpHGL.jpg)**Tributyrin Supplement 550mg Advanced Butyrate Form for Gut Health 60% Standardized More Effective Delivery Than Sodium Butyrate 90 Capsules Non-GMO & Gluten Free Postbiotic Supplement**ForestVibe**$21.86**4.6★**▲ 110%**](https://www.amazon.com/dp/B0G64ZWGLF) [![Doctors Best High Absorption Postbiotic Butyrate Gut Health Supplement - Tributyrin 90% (as CoreBiome) 300 mg Digestive Health Support for Men & Women Vegan Gluten Free - 30 Liquid Veggie Caps](https://m.media-amazon.com/images/I/41cmFZh92zL.jpg)**Doctors Best High Absorption Postbiotic Butyrate Gut Health Supplement - Tributyrin 90% (as CoreBiome) 300 mg Digestive Health Support for Men & Women Vegan Gluten Free - 30 Liquid Veggie Caps**Doctor's BEST**$22.05**4.3★**▲ 93%**](https://www.amazon.com/dp/B0F1B7HCLW)

**~~View all trending →~~**

## **What buyers say about tributyrin**

What buyers praise and complain about, mined from review topics.

### **What buyers love **

**Regulates Digestion**18%

*“Great digestive enhancer”*

**Nutritional Content**8%

*“this supplement was recommended”*

**Quality-Overall**7%

*“Great Product, Works as advertised”*

**Ease Of Chewing/Swallowing**7%

*“so I did not have any issues with swallowing them”*

**Value For Money**5%

*“a good value”*

**Efficiency**5%

*“I think it's effective for me”*

**Acid Regulator/Stomach Ache Relief**4%

*“This has helped my stomach a lot”*

**Ingredients-Overall**4%

*“Good ingredients”*

**Vitamin**4%

*“Great for adding to daily supplement intake”*

**Ease Of Use**4%

*“it's easy to use”*

### **What buyers complain about **

**Regulates Digestion**6%

*“Causes digestive issues”*

**Smell**6%

*“off smell to it”*

**Dosage**5%

*“certainly not 800mg”*

**Advertised Vs Actual Product**5%

*“the mismatch between the listing”*

**Taste-Overall**4%

*“the pill is tasteless”*

**Side Effects**3%

*“broke out in hives”*

**Ingredients-Overall**3%

*“Any ingredients in this product is so small it could never have a change in any body function”*

**Functionality-Overall**2%

*“Does not work”*

**Size-Overall**2%

*“The capsules are somewhat large”*

**Weight Loss**2%

*“It did not help me lose weight”*

### **Top return reasons **

**Smell**50%

**Color**50%

## **Common questions**

<dl>

<dt>**Is tributyrin profitable to sell on Amazon United States?**</dt><dd>The niche generates $415K/yr across 17 tracked products. 2 of 5 products launched in the last 360 days are still selling. 90-day search growth is +25.7%. Flapen's verdict: Worth a look (65/100).</dd>

<dt>**How competitive is the tributyrin niche?**</dt><dd>15 brands and 26 sellers compete. The top 5 products take 67% of clicks and top 5 brands hold 73% of demand.</dd>

<dt>**What do buyers complain about in tributyrin?**</dt><dd>Top complaints mined from reviews: Regulates Digestion, Smell, Dosage. The return rate is 0.0%.</dd>

<dt>**When does demand for tributyrin peak?**</dt><dd>Demand peaks in May–Jun–Jul; the busiest month runs 1.9× the quietest.</dd>

<dt>**What does it cost to enter the tributyrin niche?**</dt><dd>Listings span $14.58–$80.24; the average listing price is $31.73 (sweet spot $15–$100). The average incumbent carries 201 reviews — the moat a new listing must climb.</dd>

</dl>

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