---
title: "Pyrilamine Maleate — $214K/yr Amazon US Niche (2026) - Flapen"
canonical_url: "https://flapen.com/research/us/health-household/pyrilamine-maleate"
last_updated: "2026-08-11T03:28:58.903Z"
locale: en
meta:
  description: "Niche score 42/100 · $214K/yr market · 172K searches/yr · $14.82 avg price. Doesn't clear our bar today. Data updated Jul 2026."
  "og:description": "Niche score 42/100 · $214K/yr market · 172K searches/yr · $14.82 avg price. Doesn't clear our bar today. Data updated Jul 2026."
  "og:title": "Pyrilamine Maleate — $214K/yr Amazon US Niche (2026) - Flapen"
---

# **pyrilamine maleate**

**Skip it**

Brand-locked demand (top 5 brands take 98% of clicks) — this niche doesn't clear our bar today.

Market size 41Growth 32Conversion 81Competition 9Returns 100Price range 77Avg price 74Brand share 5Review moat 23Quality gap 21

**Returns**

**Incredible****0.1%**

return rate — above 5% kills the launch gate

**Conversion**

**Great****8.4%**

search→purchase rate — share of searches ending in a sale

**Price range**

**Great****$6.31–$45.30**

cheapest to priciest tracked listing — scored on the share inside $15–$100

**Avg price**

**Good****$14.82**

avg listing price — sweet spot $15–$100

**Market size**

**Okay****$214K**

$214K/yr · 172K searches

**Growth**

**Okay****+5.6%**

90-day search growth — must beat 0% to launch

**Review moat**

**Bad****8,557.56**

avg incumbent reviews — the moat a new listing must climb

**Quality gap**

**Bad****4.7★**

avg incumbent rating — lower means beatable quality

**Competition**

**Bad****90%**

top-5 click share — a locked-up shelf

**Brand share**

**Bad****98%**

top-5 brand share — brand-locked demand

According to Flapen's Amazon United States niche tracking, pyrilamine maleate is a $214K/yr Amazon United States market (172K searches/yr). The top 5 brands hold 98% of demand. Verdict: Skip it — 42/100.

Data updated Jul 11, 2026 · scored weekly · [~~How we score niches ~~](https://flapen.com/research/methodology)

## **pyrilamine maleate market data**

<dl>

<dt>**Units sold / yr**</dt><dd>**15K–20K**</dd><dd>avg 3,000–4,000/product</dd>

<dt>**Revenue / yr**</dt><dd>**$222K–$296K**</dd><dd>units × avg price</dd>

<dt>**Conversion rate**</dt><dd>**8.4%**</dd>

<dt>**Avg BSR**</dt><dd>**#88**</dd>

<dt>**Page quality**</dt><dd>**0%**</dd>

<dt>**Prime**</dt><dd>**100%**</dd>

<dt>**Sponsored**</dt><dd>**100%**</dd>

<dt>**Out of stock**</dt><dd>**5.1%**</dd>

<dt>**Avg brand age**</dt><dd>**61 months**</dd>

<dt>**Avg seller age**</dt><dd>**148 days**</dd>

</dl>

## **Competition & brand share**

The top 5 products capture 90% of clicks — a locked-up shelf that new listings rarely crack.

**Brands**

**6 **▲rising

**Sellers**

**59**

**Top-5 brand share**

**98%**

Top 20: 100%

**Top-5 click share**

**90%**

Top 20: 100%

**Open market**

**0%**

- Midol45% - Buscapina39% - IBgard6% - HealthA2Z5% - Pamprin4% - FLAGELI2%

## **Demand**

Weekly Amazon search volume, last 19 weeks — +5.6% search growth over the last 90 days.

4K3KSpike '26Mar '26Mar '26Apr '26May '26May '26Jun '26

[**Open Trend **](https://flapen.com/research/us/health-household/pyrilamine-maleate/trend)

## **Top pyrilamine maleate search terms**

- **buscapina**46K/yr+17.3%4.7% conv. - **buscopan**34K/yr-8.4%1.4% conv. - **midol caffeine free**27K/yr+37.8%17.1% conv. - **buscapina compuesta**25K/yr+5.2%3.2% conv. - **caffeine free midol**5K/yr+12.5%24.4% conv. - **buscopan ibs relief**7K/yr-12.0%1.1% conv. - **buscapina duo para dolor de estmago**7K/yr-39.4%2.2% conv. - **pyrilamine maleate**4K/yr+11.4%1.8% conv. - **buscapina fem menstrual**3K/yr-12.1%2.9% conv. - **dorival**3K/yr-10.3%1.1% conv. [**All search terms **](https://flapen.com/research/us/health-household/pyrilamine-maleate/search-terms)

## **Top pyrilamine maleate products on Amazon**

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

0%10%$21K20%$43K30%$64K40%$86K1001K10K100K Reviews — right = deep review moatMarket share (90d) ≈ est. sales

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 9 tracked products in this niche — three views at once, no toggling.

### **Top sellers**

by 90-day click share

[1![Buscapina Menstrual Cramps Headaches Joint Aches Pain Relief Caplets Acetaminophen 500mg 24 Count Fast-Acting Period Pain & Bloating Relief - Alivio Rpido Clicos](https://m.media-amazon.com/images/I/41onkXyFqML.jpg)**Buscapina Menstrual Cramps Headaches Joint Aches Pain Relief Caplets Acetaminophen 500mg 24 Count Fast-Acting Period Pain & Bloating Relief - Alivio Rpido Clicos**Buscapina**$10.36**4.7★1,354 rev](https://www.amazon.com/dp/B09RGLVCFY) [2![Midol Complete Caffeine Free Caplets 24ct: Midol Complete Caffeine Free Menstrual Pain Relief Caplets with Acetaminophen Provides Headache Relief and Period Cramps Relief 24 Count](https://m.media-amazon.com/images/I/41Wpe--nnhL.jpg)**Midol Complete Caffeine Free Caplets 24ct: Midol Complete Caffeine Free Menstrual Pain Relief Caplets with Acetaminophen Provides Headache Relief and Period Cramps Relief 24 Count**Midol**$6.31**4.8★2,214 rev](https://www.amazon.com/dp/B08WD8Z9B1) [3![Midol Complete Menstrual Pain Relief Caplets 40 Count - Provides Cramp Headache and Bloating Relief](https://m.media-amazon.com/images/I/41W1smVvf8L.jpg)**Midol Complete Menstrual Pain Relief Caplets 40 Count - Provides Cramp Headache and Bloating Relief**Midol**$8.25**4.8★19,404 rev](https://www.amazon.com/dp/B000GGFYRW) [4![HealthA2Z Menstrual Complete Pain Relief Tablets | Relieves Cramps Bloating Fatigue Backache & Headache (90 Counts)](https://m.media-amazon.com/images/I/41Mt9AmHYkL.jpg)**HealthA2Z Menstrual Complete Pain Relief Tablets | Relieves Cramps Bloating Fatigue Backache & Headache (90 Counts)**HealthA2Z**$7.83**4.8★900 rev](https://www.amazon.com/dp/B0DLQCFHL2) [5![IBgard Gut Health Supplement Peppermint Oil Capsules for Abdominal Comfort 12 Capsules](https://m.media-amazon.com/images/I/4118FByeSPL.jpg)**IBgard Gut Health Supplement Peppermint Oil Capsules for Abdominal Comfort 12 Capsules**IBgard**$11.08**4.5★19,181 rev](https://www.amazon.com/dp/B0CS6XZHRQ)

**~~View all top sellers →~~**

### **Newest**

by launch date

[![HealthA2Z Menstrual Complete Pain Relief Tablets | Relieves Cramps Bloating Fatigue Backache & Headache (90 Counts)](https://m.media-amazon.com/images/I/41Mt9AmHYkL.jpg)**HealthA2Z Menstrual Complete Pain Relief Tablets | Relieves Cramps Bloating Fatigue Backache & Headache (90 Counts)**HealthA2Z**$7.83**900 rev1y ago](https://www.amazon.com/dp/B0DLQCFHL2) [![Mens Dress Shoes Comfort Business Casual Premium Leather Oxford Shoes Fashion Dress Sneakers Office Working Driving Walking Derby Shoe Black 12 US](https://m.media-amazon.com/images/I/51sEz7wKNVL.jpg)**Mens Dress Shoes Comfort Business Casual Premium Leather Oxford Shoes Fashion Dress Sneakers Office Working Driving Walking Derby Shoe Black 12 US**FLAGELI**$45.30**1,139 rev2y ago](https://www.amazon.com/dp/B0D3D177QR) [![IBgard Gut Health Supplement Peppermint Oil Capsules for Abdominal Comfort 12 Capsules](https://m.media-amazon.com/images/I/4118FByeSPL.jpg)**IBgard Gut Health Supplement Peppermint Oil Capsules for Abdominal Comfort 12 Capsules**IBgard**$11.08**19,181 rev2y ago](https://www.amazon.com/dp/B0CS6XZHRQ) [![Buscapina Menstrual Cramps Headaches Joint Aches Pain Relief Caplets Acetaminophen 500mg 24 Count Fast-Acting Period Pain & Bloating Relief - Alivio Rpido Clicos](https://m.media-amazon.com/images/I/41onkXyFqML.jpg)**Buscapina Menstrual Cramps Headaches Joint Aches Pain Relief Caplets Acetaminophen 500mg 24 Count Fast-Acting Period Pain & Bloating Relief - Alivio Rpido Clicos**Buscapina**$10.36**1,354 rev4y ago](https://www.amazon.com/dp/B09RGLVCFY) [![Midol Complete Caffeine Free Caplets 24ct: Midol Complete Caffeine Free Menstrual Pain Relief Caplets with Acetaminophen Provides Headache Relief and Period Cramps Relief 24 Count](https://m.media-amazon.com/images/I/41Wpe--nnhL.jpg)**Midol Complete Caffeine Free Caplets 24ct: Midol Complete Caffeine Free Menstrual Pain Relief Caplets with Acetaminophen Provides Headache Relief and Period Cramps Relief 24 Count**Midol**$6.31**2,214 rev5y ago](https://www.amazon.com/dp/B08WD8Z9B1)

**~~View all new products →~~**

### **Trending**

90-day click momentum

[![Mens Dress Shoes Comfort Business Casual Premium Leather Oxford Shoes Fashion Dress Sneakers Office Working Driving Walking Derby Shoe Black 12 US](https://m.media-amazon.com/images/I/51sEz7wKNVL.jpg)**Mens Dress Shoes Comfort Business Casual Premium Leather Oxford Shoes Fashion Dress Sneakers Office Working Driving Walking Derby Shoe Black 12 US**FLAGELI**$45.30**4.4★**▲ 377%**](https://www.amazon.com/dp/B0D3D177QR) [![IBgard Gut Health Supplement Peppermint Oil Capsules for Abdominal Comfort 12 Capsules](https://m.media-amazon.com/images/I/4118FByeSPL.jpg)**IBgard Gut Health Supplement Peppermint Oil Capsules for Abdominal Comfort 12 Capsules**IBgard**$11.08**4.5★**▲ 181%**](https://www.amazon.com/dp/B0CS6XZHRQ) [![Midol Complete Menstrual Pain Relief Caplets 40 Count - Provides Cramp Headache and Bloating Relief](https://m.media-amazon.com/images/I/41W1smVvf8L.jpg)**Midol Complete Menstrual Pain Relief Caplets 40 Count - Provides Cramp Headache and Bloating Relief**Midol**$8.25**4.8★**▲ 47%**](https://www.amazon.com/dp/B000GGFYRW) [![HealthA2Z Menstrual Complete Pain Relief Tablets | Relieves Cramps Bloating Fatigue Backache & Headache (90 Counts)](https://m.media-amazon.com/images/I/41Mt9AmHYkL.jpg)**HealthA2Z Menstrual Complete Pain Relief Tablets | Relieves Cramps Bloating Fatigue Backache & Headache (90 Counts)**HealthA2Z**$7.83**4.8★**▲ 45%**](https://www.amazon.com/dp/B0DLQCFHL2) [![Pamprin Multi-Symptom Formula with Acetaminophen Menstrual Period Symptoms Relief including Cramps Pain Bloating and Irritability 40 Caplets](https://m.media-amazon.com/images/I/41TZbu2RUfL.jpg)**Pamprin Multi-Symptom Formula with Acetaminophen Menstrual Period Symptoms Relief including Cramps Pain Bloating and Irritability 40 Caplets**Pamprin**$6.99**4.7★**▲ 39%**](https://www.amazon.com/dp/B0014G59F0)

**~~View all trending →~~**

## **What buyers say about pyrilamine maleate**

What buyers praise and complain about, mined from review topics.

### **What buyers love **

**Efficiency**14%

*“Works well”*

**Regulates Digestion**13%

*“But what is so wonderful is that the capsule does not dissolve until it gets to your intestines where it really counts”*

**Acid Regulator/Stomach Ache Relief**13%

*“It really does help with stomach issues”*

**Menstrual Issues**8%

*“Really good for period cramps”*

**Quality-Overall**6%

*“no complaints so far”*

**Value For Money**5%

*“affordable”*

**Muscle Pain Relief**5%

*“relaxes my muscles through that time of the month”*

**Caffeine Content**5%

*“this caffeine free option is great”*

**Natural Ingredients**3%

*“I love that its natural”*

**Advertised Vs Actual Product**3%

*“Works as advertised”*

### **What buyers complain about **

**Functionality-Overall**18%

*“Not effective enough”*

**Side Effects**11%

*“It made my stomach bloating worse”*

**Value For Money**10%

*“I wish it was more affordable”*

**Acid Regulator/Stomach Ache Relief**7%

*“irritates my stomach badly”*

**Pain Relief-Overall**7%

*“it does not provide me with any relief”*

**Dosage**6%

*“Really stopped my frequent (10 x)”*

**Regulates Digestion**5%

*“Not for GERD”*

**Muscle Pain Relief**5%

*“Doesnt really seem to help with cramps”*

**Sleep Quality**3%

*“dont take at night”*

**Joint Pain**2%

*“Works okay, not the best for period pain”*

### **Top return reasons **

**Functionality-Overall**27%

**Advertised Vs Actual Product**14%

**Feet Fit**5%

**Dosage**5%

**Size-Overall**5%

**Ingredients-Overall**4%

**Ease Of Chewing/Swallowing**4%

**Joint Pain**3%

**Certifications**3%

**Product Condition**3%

## **Common questions**

<dl>

<dt>**Is pyrilamine maleate profitable to sell on Amazon United States?**</dt><dd>The niche generates $214K/yr across 9 tracked products. 90-day search growth is +5.6%. Flapen's verdict: Skip it (42/100).</dd>

<dt>**How competitive is the pyrilamine maleate niche?**</dt><dd>6 brands and 59 sellers compete. The top 5 products take 90% of clicks and top 5 brands hold 98% of demand.</dd>

<dt>**What do buyers complain about in pyrilamine maleate?**</dt><dd>Top complaints mined from reviews: Functionality-Overall, Side Effects, Value For Money. The return rate is 0.1%.</dd>

<dt>**What does it cost to enter the pyrilamine maleate niche?**</dt><dd>Listings span $6.31–$45.30; the average listing price is $14.82 (sweet spot $15–$100). The average incumbent carries 8,558 reviews — the moat a new listing must climb.</dd>

</dl>

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