---
title: "Phosphatidylserine — $2.9M/yr Amazon US Niche (2026) - Flapen"
canonical_url: "https://flapen.com/research/us/health-household/phosphatidylserine"
last_updated: "2026-08-10T22:52:03.950Z"
locale: en
meta:
description: "Niche score 67/100 · $2.9M/yr market. A failed launch gate (market size, growth, or returns) keeps it on the watch list. Data updated Jul 2026."
"og:description": "Niche score 67/100 · $2.9M/yr market. A failed launch gate (market size, growth, or returns) keeps it on the watch list. Data updated Jul 2026."
"og:title": "Phosphatidylserine — $2.9M/yr Amazon US Niche (2026) - Flapen"
---
# **phosphatidylserine**
**Worth a look**
Shows low returns (0.0%), but a failed launch gate (market size, growth, or returns) keeps it on the watch list.
Market size 96Growth 23Conversion 95Competition 42Returns 100Price range 95Avg price 95Brand share 70Review moat 53Quality gap 40
**Returns**
**Incredible****0.0%**
return rate — above 5% kills the launch gate
**Market size**
**Incredible****$2.9M**
$2.9M/yr · 731K searches
**Conversion**
**Incredible****12.2%**
search→purchase rate — share of searches ending in a sale
**Avg price**
**Incredible****$32.51**
avg listing price — sweet spot $15–$100
**Price range**
**Incredible****$14.75–$79.26**
cheapest to priciest tracked listing — scored on the share inside $15–$100
**Brand share**
**Good****63%**
top-5 brand share — brands hold most of the demand
**Review moat**
**Good****1,383.57**
avg incumbent reviews — the moat a new listing must climb
**Competition**
**Okay****60%**
top-5 click share — leaders hold, buyers still browse
**Quality gap**
**Okay****4.5★**
avg incumbent rating — lower means beatable quality
**Growth**
**Bad****-3.8%**
90-day search growth — must beat 0% to launch
According to Flapen's Amazon United States niche tracking, phosphatidylserine is a $2.9M/yr Amazon United States market (731K searches/yr). The top 5 brands hold 63% of demand. Verdict: Worth a look — 67/100.
Data updated Jul 27, 2026 · scored weekly · [~~How we score niches ~~](https://flapen.com/research/methodology)
## **phosphatidylserine market data**
- **Units sold / yr**
- **80K–100K**
- avg 3,000–4,000/product
- **Revenue / yr**
- **$2.6M–$3.3M**
- units × avg price
- **Conversion rate**
- **12.2%**
- **Avg BSR**
- **#1,216**
- **Page quality**
- **0%**
- **Prime**
- **100%**
- **Sponsored**
- **71%**
- **Out of stock**
- **4.3%**
- **Avg brand age**
- **66 months**
- **Avg seller age**
- **154 days**
## **Competition & brand share**
The top 5 products take 60% of clicks — established leaders, but buyers still shop beyond them.
**Brands**
**14 **▼falling
**Sellers**
**30**
**Top-5 brand share**
**63%**
Top 20: 92%
**Top-5 click share**
**60%**
Top 20: 99%
**Open market**
**29%**
- Double Wood Supplements21% - Nutricost14% - NOW Foods11% - THORNE10% - --8% - Toniiq7%
## **Demand & seasonality**
Weekly Amazon search volume, last 104 weeks — -3.8% search growth over the last 90 days.
18K13KBlack Friday '25Spike '26 seasonSepDecMarJunAugNovMarMay
No pronounced peak months · busiest ÷ quietest = 1.4×
[**Open Trend **](https://flapen.com/research/us/health-household/phosphatidylserine/trend)
## **Top phosphatidylserine search terms**
- **phosphatidylserine**490K/yr-1.0%10.2% conv. - **phosphatidylserine supplement**103K/yr-11.4%8.1% conv. - **ps100**17K/yr+12.0%8.0% conv. - **phosphatidylserine 100mg**18K/yr-21.2%8.8% conv. - **phosphatidylserine 300mg**17K/yr-35.0%10.4% conv. - **fosfatidilserina**13K/yr-7.3%2.5% conv. - **phosphatidylserine 400mg**5K/yr+163.1%11.7% conv. - **phosphatidyl serine**13K/yr-4.4%9.8% conv. - **thorne phosphatidylserine**9K/yr-1.6%17.9% conv. - **phosphatidylserine 200mg**7K/yr-34.5%8.8% conv. [**All search terms **](https://flapen.com/research/us/health-household/phosphatidylserine/search-terms)
## **Top phosphatidylserine products on Amazon**
Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.
0%10%$291K20%$582K30%$873K40%$1.2M101001K10K100K Reviews — right = deep review moatMarket share (90d) ≈ est. sales
Beatable (≤4.3★) Contested Strong incumbent (>4.7★)
All 21 tracked products in this niche — three views at once, no toggling.
### **Top sellers**
by 90-day click share
[1**PhosphatidylSerine Supplement 300mg Per Serving 120 Capsules (Phosphatidyl Serine Complex) by Double Wood**Double Wood Supplements**$19.76**4.5★6,095 rev](https://www.amazon.com/dp/B079YF1K1B) [2**Nutricost Phosphatidylserine (400mg) 120 Capsules Gluten Free**Nutricost**$23.66**4.5★1,278 rev](https://www.amazon.com/dp/B08XYDDXDC) [3**THORNE - Phosphatidylserine - Supports Healthy Brain Function Memory & Focus - Helps Regulate Cortisol During Stress* - Third-Party Certified - Gluten-Free Dairy-Free - 60 Capsules**THORNE**$66.37**4.5★273 rev](https://www.amazon.com/dp/B000FGZG4O) [4**Phosphatidylserine Supplement 400mg Serving 240 Capsules Soy Free Sunflower Lecithin Source**--**$24.17**4.6★1,348 rev](https://www.amazon.com/dp/B0971RLCR2) [5**Toniiq Phosphatidylserine - 400mg Formula - Worlds First 50% Purity - Highest Purity in the US - Soy Free Phosphatidylserine Supplement - 90 Veggie Capsules**Toniiq**$24.39**4.6★1,422 rev](https://www.amazon.com/dp/B08LF5G6J1)
**~~View all top sellers →~~**
### **Newest**
by launch date
[**Micro Ingredients Phosphatidylserine 600 mg Per Serving 240 Capsules | Soy Free Phosphatidylserine Supplement with Choline Lions Mane Ginkgo & Omega-3 | Non-GMO Gluten Free**Micro Ingredients**$21.81**22 rev6mo ago](https://www.amazon.com/dp/B0GDS4HHYZ) [**Micro Ingredients Lions Mane+ with Omega-3 EPA DHA & Phosphatidylserine 240 Softgels with MCT Oil for Better Absorption Fruiting Body & Mycelium Superfood Mushroom Extract Lemon Flavored**Micro Ingredients**$20.94**123 rev1y ago](https://www.amazon.com/dp/B0FJ46RC8P) [**ML Naturals Phosphatidyl Serine 200mg (Per Serving) 120 Vegetable Capsules Non-GMO Supports Memory & Brain Function**ML Naturals**$14.75**181 rev3y ago](https://www.amazon.com/dp/B0BW51QL8M) [**BulkSupplements.com Phosphatidylserine Capsules - Phosphatidylserine Supplement - Gluten Free 1 Capsule per Serving (60mg) 240 Capsules (Pack of 1)**BulkSupplements**$24.26**86 rev3y ago](https://www.amazon.com/dp/B0BB8D4ND9) [**NOW Foods Supplements Soy-Free Phosphatidyl Serine (150mg) Brain Health* 60 Veg Capsules**NOW Foods**$26.51**392 rev4y ago](https://www.amazon.com/dp/B09MSPXCMT)
**~~View all new products →~~**
### **Trending**
90-day click momentum
[**Micro Ingredients Phosphatidylserine 600 mg Per Serving 240 Capsules | Soy Free Phosphatidylserine Supplement with Choline Lions Mane Ginkgo & Omega-3 | Non-GMO Gluten Free**Micro Ingredients**$21.81**4.6★**▲ 245%**](https://www.amazon.com/dp/B0GDS4HHYZ) [**Integrative Therapeutics Cortisol Manager - Balance Cortisol & Support Relaxation for Restful Sleep* - Includes Ashwagandha & L-Theanine for Confidence with Less Stress* - 30 Tablets**Integrative Therapeutics**$25.21**4.2★**▲ 110%**](https://www.amazon.com/dp/B002D2JYYG) [**Micro Ingredients Lions Mane+ with Omega-3 EPA DHA & Phosphatidylserine 240 Softgels with MCT Oil for Better Absorption Fruiting Body & Mycelium Superfood Mushroom Extract Lemon Flavored**Micro Ingredients**$20.94**4.6★**▲ 25%**](https://www.amazon.com/dp/B0FJ46RC8P) [**NOW Foods Supplements Phosphatidyl Serine 100 mg with Phospholipid compound derived from Soy Lecithin 60 Veg Capsules**NOW Foods**$20.47**4.5★**▲ 24%**](https://www.amazon.com/dp/B0013OUQW4) [**NOW Supplements Phosphatidyl Serine 300 mg Extra Strength with Phospholipid compound derived from Soy Lecithin 50 Softgels**NOW Foods**$35.71**4.4★**▲ 16%**](https://www.amazon.com/dp/B01N26G89C)
**~~View all trending →~~**
## **What buyers say about phosphatidylserine**
What buyers praise and complain about, mined from review topics.
### **What buyers love **
**Sleep Quality**17%
*“Helps with Sleep”*
**Quality-Overall**13%
*“the quality of its supporting ingredients”*
**Stress/Anxiety**8%
*“Stress reliever”*
**Focus Enhancement**8%
*“I think it is helping my memory”*
**Vitamin**5%
*“Great vitamin”*
**Value For Money**5%
*“Worth every penny”*
**Ingredients-Overall**4%
*“The pills seem to be made of good quality ingredients”*
**Efficiency**4%
*“Effective”*
**Advertised Vs Actual Product**3%
*“As advertised”*
**Ease Of Chewing/Swallowing**3%
*“not difficult for me to swallow”*
### **What buyers complain about **
**Sleep Quality**16%
*“couldnt sleep again”*
**Functionality-Overall**11%
*“Didn't work for me”*
**Value For Money**7%
*“Waste of money”*
**Dosage**6%
*“Extremely under dosed”*
**Side Effects**5%
*“Side affects”*
**Stress/Anxiety**5%
*“My anxiety has been very bad”*
**Ingredients-Overall**3%
*“Active ingredient comes from freaking soy”*
**Advertised Vs Actual Product**3%
*“This product does not do as advertised”*
**Size-Overall**3%
*“The pills are a bit large”*
**Acid Regulator/Stomach Ache Relief**2%
*“can cause nausea”*
### **Top return reasons **
**Sleep Quality**21%
**Functionality-Overall**21%
**Value For Money**14%
**Ease Of Chewing/Swallowing**14%
**Advertised Vs Actual Product**14%
**Quality-Overall**7%
**Temperature Retention**7%
## **Common questions**
- **Is phosphatidylserine profitable to sell on Amazon United States?**
- The niche generates $2.9M/yr across 21 tracked products. 0 of 1 products launched in the last 360 days are still selling. 90-day search growth is -3.8%. Flapen's verdict: Worth a look (67/100).
- **How competitive is the phosphatidylserine niche?**
- 14 brands and 30 sellers compete. The top 5 products take 60% of clicks and top 5 brands hold 63% of demand.
- **What do buyers complain about in phosphatidylserine?**
- Top complaints mined from reviews: Sleep Quality, Functionality-Overall, Value For Money. The return rate is 0.0%.
- **When does demand for phosphatidylserine peak?**
- Demand is steady year-round — the busiest month runs 1.4× the quietest.
- **What does it cost to enter the phosphatidylserine niche?**
- Listings span $14.75–$79.26; the average listing price is $32.51 (sweet spot $15–$100). The average incumbent carries 1,384 reviews — the moat a new listing must climb.
## **Related niches in Health & Household**
- 76 [**cedar oil**](https://flapen.com/research/us/health-household/cedar-oil)$1.2M/yr+214.4%**Launch it**- 77 [**nutrapure glp1 cutting mix**](https://flapen.com/research/us/health-household/nutrapure-glp1-cutting-mix)$149K/yr+940.2%**Worth a look**- 77 [**dexcom g7**](https://flapen.com/research/us/health-household/dexcom-g7)$2.0M/yr+39.9%**Launch it**- 77 [**purelia**](https://flapen.com/research/us/health-household/purelia)$635K/yr+359.7%**Worth a look**- 77 [**graduation napkins**](https://flapen.com/research/us/health-household/graduation-napkins)$302K/yr+385.7%**Worth a look**- 77 [**credit card wand**](https://flapen.com/research/us/health-household/credit-card-wand)$418K/yr+101.3%**Worth a look**[**All Health & Household niches **](https://flapen.com/research/us/health-household)