---
title: "Nystatin Cream Antifungal — $207K/yr Amazon US Niche (2026) - Flapen"
canonical_url: "https://flapen.com/research/us/health-household/nystatin-cream-antifungal"
last_updated: "2026-08-06T15:53:56.502Z"
locale: en
meta:
description: "Niche score 42/100 · $207K/yr market · 161K searches/yr · $21.90 avg price. Doesn't clear our bar today. Data updated Jul 2026."
"og:description": "Niche score 42/100 · $207K/yr market · 161K searches/yr · $21.90 avg price. Doesn't clear our bar today. Data updated Jul 2026."
"og:title": "Nystatin Cream Antifungal — $207K/yr Amazon US Niche (2026) - Flapen"
---
# **nystatin cream antifungal**
**Skip it**
Brand-locked demand (top 5 brands take 100% of clicks) — this niche doesn't clear our bar today.
Market size 40Growth 21Conversion 66Competition 24Returns 99Price range 69Avg price 92Brand share 0Review moat 21Quality gap 40
**Returns**
**Incredible****0.3%**
return rate — above 5% kills the launch gate
**Avg price**
**Great****$21.90**
avg listing price — sweet spot $15–$100
**Price range**
**Good****$4.62–$127.76**
cheapest to priciest tracked listing — scored on the share inside $15–$100
**Conversion**
**Good****5.9%**
search→purchase rate — share of searches ending in a sale
**Market size**
**Okay****$207K**
$207K/yr · 161K searches
**Quality gap**
**Okay****4.5★**
avg incumbent rating — lower means beatable quality
**Competition**
**Bad****71%**
top-5 click share — a locked-up shelf
**Growth**
**Bad****-8.4%**
90-day search growth — must beat 0% to launch
**Review moat**
**Bad****10,635.68**
avg incumbent reviews — the moat a new listing must climb
**Brand share**
**Bad****100%**
top-5 brand share — brand-locked demand
According to Flapen's Amazon United States niche tracking, nystatin cream antifungal is a $207K/yr Amazon United States market (161K searches/yr). The top 5 brands hold 100% of demand. Verdict: Skip it — 42/100.
Data updated Jul 11, 2026 · scored weekly · [~~How we score niches ~~](https://flapen.com/research/methodology)
## **nystatin cream antifungal market data**
- **Units sold / yr**
- **10K–13K**
- avg 500–750/product
- **Revenue / yr**
- **$219K–$274K**
- units × avg price
- **Conversion rate**
- **5.9%**
- **Avg BSR**
- **#74**
- **Page quality**
- **0%**
- **Prime**
- **95%**
- **Sponsored**
- **95%**
- **Out of stock**
- **4.9%**
- **Avg brand age**
- **71 months**
- **Avg seller age**
- **144 days**
## **Competition & brand share**
The top 5 products capture 71% of clicks — a locked-up shelf that new listings rarely crack.
**Brands**
**4 **▼falling
**Sellers**
**74**
**Top-5 brand share**
**100%**
Top 20: 100%
**Top-5 click share**
**71%**
Top 20: 100%
**Open market**
**0%**
- McKesson55% - Nizoral41% - MED PRIDE2% - Globe Pharmacy2% - Open — no brand owns it (0%)
## **Demand**
Weekly Amazon search volume, last 40 weeks — -8.4% search growth over the last 90 days.
3K2KHoliday '25Spike '26Oct '25Nov '25Dec '25Feb '26Mar '26May '26Jun '26
[**Open Trend **](https://flapen.com/research/us/health-household/nystatin-cream-antifungal/trend)
## **Top nystatin cream antifungal search terms**
- **mckesson**70K/yr-4.8%1.8% conv. - **nizoral cream**40K/yr-16.4%5.4% conv. - **nystatin cream antifungal**16K/yr-10.8%3.2% conv. - **mckesson medical supplies**9K/yr+22.7%0.8% conv. - **mckesson antifungal cream**8K/yr-16.5%26.0% conv. - **nizoral cream ketoconazole**4K/yr+25.4%4.0% conv. - **nizoral cream antifungal**3K/yr-12.0%5.8% conv. - **mckesson medical supply**3K/yr+47.7%0.4% conv. - **mckesson antifungal cream 2 percent miconazole nitrate cream**3K/yr-27.3%22.9% conv. - **econazole antifungal cream**4K/yr-45.7%3.3% conv. [**All search terms **](https://flapen.com/research/us/health-household/nystatin-cream-antifungal/search-terms)
## **Top nystatin cream antifungal products on Amazon**
Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.
0%10%$21K20%$41K30%$62K40%$83K101001K10K100K1.0M Reviews — right = deep review moatMarket share (90d) ≈ est. sales
Beatable (≤4.3★) Contested Strong incumbent (>4.7★)
All 19 tracked products in this niche — three views at once, no toggling.
### **Top sellers**
by 90-day click share
[1**McKesson Antifungal Cream 2% Miconazole Nitrate - Relieves Itching Burning Cracking from Jock Itch Ringworm and Athlete Foot - 4 oz. 1 Count**McKesson**$8.62**4.5★9,308 rev](https://www.amazon.com/dp/B01N6GA8SQ) [2**Nizoral Psoriasis Relief Cream Maximum Strength 4 Fl Oz Relieves Itching Irritation & Redness Controls Flaking and Scaling Salicylic Acid 3%**Nizoral**$13.09**4.4★1,354 rev](https://www.amazon.com/dp/B0CP9TS8VD) [3**Nizoral Eczema Relief Cream 4 Fl Oz (Pack of 1) Relieves Dry Itchy Irritated Skin Soothes Hydrates with 7 Moisturizers Colloidal Oatmeal 2% Eczema Cream for Adults**Nizoral**$12.08**4.4★241 rev](https://www.amazon.com/dp/B0CP9RHYJR) [4**McKesson Washcloth Wipes for Adults Scented (6 Pack 576 Washcloths) Disposable Wash Cloths for Body - No-Rinse Formula with Snap Lid - Good for Incontinence and Elderly - 96 Wipes Per Pack**McKesson**$33.10**4.7★21,485 rev](https://www.amazon.com/dp/B0DGV7GQ7J) [5![McKesson Antimicrobial Lotion Hand Soap with Aloe 18 oz Pump Bottle [Pack of 1] - Herbal Scent Keeps Hands Clean and Moisturized Medical-Grade Soap](https://m.media-amazon.com/images/I/31e8JEqONFL.jpg)**McKesson Antimicrobial Lotion Hand Soap with Aloe 18 oz Pump Bottle \[Pack of 1\] - Herbal Scent Keeps Hands Clean and Moisturized Medical-Grade Soap**McKesson**$11.07**4.7★1,614 rev](https://www.amazon.com/dp/B00Q5FCQS8)
**~~View all top sellers →~~**
### **Newest**
by launch date
[**McKesson Washcloth Wipes for Adults Scented (6 Pack 576 Washcloths) Disposable Wash Cloths for Body - No-Rinse Formula with Snap Lid - Good for Incontinence and Elderly - 96 Wipes Per Pack**McKesson**$33.10**21,485 rev1y ago](https://www.amazon.com/dp/B0DGV7GQ7J) [**MED PRIDE 1% Clotrimazole Antifungal Cream 1oz- Fungus Skin Care Treatment with - Jock Itch Body Ointment - Fights Infection Sweat Rash Athletes Foot Ringworm & Relieves Itching Burning**MED PRIDE**$4.62**4,031 rev2y ago](https://www.amazon.com/dp/B0CX9J4FV3) [**Nizoral Psoriasis Relief Cream Maximum Strength 4 Fl Oz Relieves Itching Irritation & Redness Controls Flaking and Scaling Salicylic Acid 3%**Nizoral**$13.09**1,354 rev2y ago](https://www.amazon.com/dp/B0CP9TS8VD) [**Nizoral Eczema Relief Cream 4 Fl Oz (Pack of 1) Relieves Dry Itchy Irritated Skin Soothes Hydrates with 7 Moisturizers Colloidal Oatmeal 2% Eczema Cream for Adults**Nizoral**$12.08**241 rev2y ago](https://www.amazon.com/dp/B0CP9RHYJR) [**Nizoral Scalp Itch Relief Liquid Maximum Strength 2 Fl Oz Relieves Scalp Itch and Soothes Calms and Hydrates With Maximum Strength Anti-Itch Medicine (Hydrocortisone 1%)**Nizoral**$9.85**2,552 rev2y ago](https://www.amazon.com/dp/B0CP9R1ZXC)
**~~View all new products →~~**
### **Trending**
90-day click momentum
[**McKesson Patient Exam Shorts Disposable - Non-Woven Material Elastic Waist Blue - Fits 38 in to 48 in Waist Size XL 100 Count**McKesson**$127.76**3.9★**▲ 361%**](https://www.amazon.com/dp/B0733MYTHY) [![McKesson Dermal Wound Care Cleanser Spray 16 oz [1 Count] First Aid Wash Solution for Minor Injuries Cuts Burns Scrapes Sores](https://m.media-amazon.com/images/I/31XUj7FQuIL.jpg)**McKesson Dermal Wound Care Cleanser Spray 16 oz \[1 Count\] First Aid Wash Solution for Minor Injuries Cuts Burns Scrapes Sores**McKesson**$10.68**4.7★**▲ 59%**](https://www.amazon.com/dp/B00PV6JMES) [![McKesson Ultra Briefs [72 Count] Size L 45-58 in. Incontinence Adult Diapers Heavy Absorbency Unisex Disposable Elastic Leg Gathers and Contoured Fit for Men and Women](https://m.media-amazon.com/images/I/41eGtNmlwnL.jpg)**McKesson Ultra Briefs \[72 Count\] Size L 45-58 in. Incontinence Adult Diapers Heavy Absorbency Unisex Disposable Elastic Leg Gathers and Contoured Fit for Men and Women**McKesson**$43.80**4.1★**▲ 54%**](https://www.amazon.com/dp/B01M0YRW98) [**McKesson Adhesive Bandages Sterile Fabric Patch 2 in x 4 in 50 Count 1 Pack**McKesson**$7.78**4.6★**▲ 41%**](https://www.amazon.com/dp/B07K3218FT) [**MED PRIDE 1% Clotrimazole Antifungal Cream 1oz- Fungus Skin Care Treatment with - Jock Itch Body Ointment - Fights Infection Sweat Rash Athletes Foot Ringworm & Relieves Itching Burning**MED PRIDE**$4.62**4.5★**▲ 28%**](https://www.amazon.com/dp/B0CX9J4FV3)
**~~View all trending →~~**
## **What buyers say about nystatin cream antifungal**
What buyers praise and complain about, mined from review topics.
### **What buyers love **
**Quality-Overall**13%
*“Great quality, exactly as described, and arrived on time”*
**Efficiency**13%
*“Works quickly”*
**Smell**9%
*“Great smell”*
**Value For Money**8%
*“Fairly priced”*
**Allergies**7%
*“no irritation at all”*
**Advertised Vs Actual Product**6%
*“As described”*
**Hair Growth**4%
*“does hold my hair in place”*
**Cleansing**3%
*“Cleans hair well”*
**Ease Of Use**3%
*“Easy to use”*
**Soft Feel**2%
*“Nice and soft”*
### **What buyers complain about **
**Allergies**15%
*“Allergic reaction”*
**Functionality-Overall**13%
*“Not effective”*
**Smell**8%
*“Scent too strong”*
**Moist/Dry**5%
*“Almost dry, right out of the box”*
**Value For Money**4%
*“Waste of Money”*
**Adhesion/Stickiness**3%
*“Horrible adhesion”*
**Size-Overall**2%
*“Larger than normal”*
**Thickness**2%
*“thick it is - clogging my pores”*
**Symptom Reduction**2%
*“this treatment is not going to help”*
**Quality-Overall**2%
*“Junk”*
### **Top return reasons **
**Functionality-Overall**21%
**Size-Overall**11%
**Leak-Proof**10%
**Smell**10%
**Advertised Vs Actual Product**8%
**Value For Money**6%
**Damage/Burn Hair**4%
**Ingredients-Overall**4%
**Product Condition**3%
**Moist/Dry**3%
## **Common questions**
- **Is nystatin cream antifungal profitable to sell on Amazon United States?**
- The niche generates $207K/yr across 19 tracked products. 90-day search growth is -8.4%. Flapen's verdict: Skip it (42/100).
- **How competitive is the nystatin cream antifungal niche?**
- 4 brands and 74 sellers compete. The top 5 products take 71% of clicks and top 5 brands hold 100% of demand.
- **What do buyers complain about in nystatin cream antifungal?**
- Top complaints mined from reviews: Allergies, Functionality-Overall, Smell. The return rate is 0.3%.
- **What does it cost to enter the nystatin cream antifungal niche?**
- Listings span $4.62–$127.76; the average listing price is $21.90 (sweet spot $15–$100). The average incumbent carries 10,636 reviews — the moat a new listing must climb.
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