---
title: "Methylfolate B12 — $22K/mo Amazon US Product Research (2026)"
canonical_url: "https://flapen.com/research/us/health-household/methylfolate-b12"
last_updated: "2026-08-12T13:23:15.923Z"
locale: en
meta:
  description: "Amazon product research for methylfolate b12: $22K/mo market, demand, competition, pricing, reviews & the verdict. Know if it's worth selling — Flapen."
  "og:description": "Amazon product research for methylfolate b12: $22K/mo market, demand, competition, pricing, reviews & the verdict. Know if it's worth selling — Flapen."
  "og:title": "Methylfolate B12 — $22K/mo Amazon US Product Research (2026)"
---

# **Methylfolate B12**

**Skip it**

Brand-locked demand (top 5 brands take 94% of clicks) — this niche doesn't clear our bar today.

Market size 48Growth 20Conversion 96Competition 21Returns 100Price range 67Avg price 84Brand share 16Review moat 25Quality gap 20

**Returns**

**Incredible****0.0%**

return rate — above 5% kills the launch gate

**Conversion**

**Incredible****13.1%**

search→purchase rate — share of searches ending in a sale

**Avg price**

**Great****$18.67**

avg listing price — sweet spot $15–$100

**Price range**

**Good****$8.35–$28.54**

cheapest to priciest tracked listing — scored on the share inside $15–$100

**Market size**

**Okay****$259K**

$259K/yr · 106K searches

**Review moat**

**Bad****4,324.93**

avg incumbent reviews — the moat a new listing must climb

**Competition**

**Bad****75%**

top-5 click share — a locked-up shelf

**Growth**

**Bad****-9.6%**

90-day search growth — must beat 0% to launch

**Quality gap**

**Bad****4.7★**

avg incumbent rating — lower means beatable quality

**Brand share**

**Bad****94%**

top-5 brand share — brand-locked demand

## **Is methylfolate b12 profitable on Amazon?**

According to Flapen's Amazon United States niche tracking, methylfolate b12 is a $259K/yr Amazon United States market (106K searches/yr). The top 5 brands hold 94% of demand. Demand peaks in Jan–Feb–Mar–Sep. Verdict: Skip it — 45/100.

Data updated Jul 28, 2026 · scored weekly · [~~How we score niches ~~](https://flapen.com/research/methodology)

## **methylfolate b12 market size & sales**

Units sold, revenue, conversion and listing quality across the tracked shelf.

<dl>

<dt>**Units sold / yr**</dt><dd>**15K–20K**</dd><dd>avg 1,250–1,500/product</dd>

<dt>**Revenue / yr**</dt><dd>**$280K–$373K**</dd><dd>units × avg price</dd>

<dt>**Conversion rate**</dt><dd>**13.1%**</dd>

<dt>**Avg BSR**</dt><dd>**#232**</dd>

<dt>**Page quality**</dt><dd>**0%**</dd>

<dt>**Prime**</dt><dd>**100%**</dd>

<dt>**Sponsored**</dt><dd>**100%**</dd>

<dt>**Out of stock**</dt><dd>**0.0%**</dd>

<dt>**Avg brand age**</dt><dd>**79 months**</dd>

<dt>**Avg seller age**</dt><dd>**169 days**</dd>

</dl>

## **Competition: brands, sellers & click share**

The top 5 products capture 75% of clicks — a locked-up shelf that new listings rarely crack.

**Brands**

**9 **▲rising

**Sellers**

**558**

**Top-5 brand share**

**94%**

Top 20: 100%

**Top-5 click share**

**75%**

Top 20: 100%

**Open market**

**4%**

- Jarrow Formulas61% - Triquetra Health16% - Seeking Health7% - Nutricost6% - Pure Encapsulations4% - Life Extension2% - Open — no brand owns it (3 brands, 4%)

## **methylfolate b12 demand & seasonality**

Weekly Amazon search volume, last 101 weeks — -9.6% search growth over the last 90 days.

60K40KSpike '24Spike '25 seasonDecMarJunAugNovMarMay

Peak months: Jan, Feb, Mar, Sep · busiest ÷ quietest = 2.6×

[**Open Trend **](https://flapen.com/research/us/health-household/methylfolate-b12/trend)

## **Top methylfolate b12 search terms shoppers use**

The exact queries shoppers type, with yearly volume, growth and conversion.

- **jarrow methyl b-12 & methyl folate**39K/yr-24.1%16.6% conv. - **methylfolate b12**20K/yr+27.5%6.7% conv. - **methyl b12 with l-methylfolate**9K/yr-31.1%12.9% conv. - **methylated b12 and folate**11K/yr+4.6%6.8% conv. - **methylated folate and b12**6K/yr+36.0%7.4% conv. - **methyl folate b12**6K/yr-3.0%6.3% conv. - **b12 methylfolate**5K/yr+0.7%9.2% conv. - **jarrow b12 folate**3K/yr+34.5%21.9% conv. - **methyl b12 folate**4K/yr+0.4%7.9% conv. - **jarrow b12 methyl folate chewable**3K/yr-62.3%19.7% conv. [**All search terms **](https://flapen.com/research/us/health-household/methylfolate-b12/search-terms)

## **Top methylfolate b12 products & what they sell for**

Every tracked product — its share of the shelf, its review moat, and what it sells for.

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

0%10%$26K20%$52K30%$78K40%$104K101001K10K100K Reviews — right = deep review moatMarket share (90d) ≈ est. sales

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 14 tracked products in this niche — three views at once, no toggling.

### **Top sellers**

by 90-day click share

[1![Jarrow Formulas Methyl B-12 & Methyl Folate Bioactive Vitamin B9 and Vitamin B12 Supplement Supports Cellular Energy Production Healthy Brain Function & Metabolism 60 Chewable Tablets 60 Servings](https://m.media-amazon.com/images/I/41QeoWNZozL.jpg)**Jarrow Formulas Methyl B-12 & Methyl Folate Bioactive Vitamin B9 and Vitamin B12 Supplement Supports Cellular Energy Production Healthy Brain Function & Metabolism 60 Chewable Tablets 60 Servings**Jarrow Formulas**$28.54**4.7★2,592 rev](https://www.amazon.com/dp/B00OGXIGOE) [2![Jarrow Formulas Methyl B-12 & Methyl Folate Bioactive Vitamin B9 & Vitamin B12 Supplement Supports Cellular Energy Production Healthy Brain Function & Metabolism 100 Chewable Tablets 100 Servings](https://m.media-amazon.com/images/I/41i17O3xpgL.jpg)**Jarrow Formulas Methyl B-12 & Methyl Folate Bioactive Vitamin B9 & Vitamin B12 Supplement Supports Cellular Energy Production Healthy Brain Function & Metabolism 100 Chewable Tablets 100 Servings**Jarrow Formulas**$13.68**4.6★7,791 rev](https://www.amazon.com/dp/B01IJR5VM2) [3![L Methyl Folate 15mg Plus Methyl B12 Cofactor High Potency Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms of Vitamin B9 & B12 (60 Capsules 60 Servings)](https://m.media-amazon.com/images/I/51RcsVNnQ7L.jpg)**L Methyl Folate 15mg Plus Methyl B12 Cofactor High Potency Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms of Vitamin B9 & B12 (60 Capsules 60 Servings)**Triquetra Health**$21.67**4.6★9,407 rev](https://www.amazon.com/dp/B0938NKV1G) [4![Seeking Health Methyl B12 with L-Methylfolate - MTHFR Support Supplement - Methylation Support Supplement - Lozenges to Support Brain Health & Energy - 60 Lozenges](https://m.media-amazon.com/images/I/31gLlDaOZqL.jpg)**Seeking Health Methyl B12 with L-Methylfolate - MTHFR Support Supplement - Methylation Support Supplement - Lozenges to Support Brain Health & Energy - 60 Lozenges**Seeking Health**$25.44**4.7★2,664 rev](https://www.amazon.com/dp/B00822JNTC) [5![Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps](https://m.media-amazon.com/images/I/416hBeAHI9L.jpg)**Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps**Nutricost**$11.10**4.7★154 rev](https://www.amazon.com/dp/B0FNFR1MPT)

**~~View all top sellers →~~**

### **Newest**

by launch date

[![Sports Research 5-MTHF Methyl Folate w/Methylated B12 90 Count Plantgels](https://m.media-amazon.com/images/I/41N-zWwUQuL.jpg)**Sports Research 5-MTHF Methyl Folate w/Methylated B12 90 Count Plantgels**Sports Research**$21.38**25 rev4mo ago](https://www.amazon.com/dp/B0GQXDQHQH) [![Vocks L Methylfolate 15mg | 5-MTHF + Methyl B12 | High Potency Methylfolate Supplement | Active Methylated Folate Vitamin B9 | MTHFR Supplement| Folate Supplement for Women & Men | 90 Capsules](https://m.media-amazon.com/images/I/41Juex1gneL.jpg)**Vocks L Methylfolate 15mg | 5-MTHF + Methyl B12 | High Potency Methylfolate Supplement | Active Methylated Folate Vitamin B9 | MTHFR Supplement| Folate Supplement for Women & Men | 90 Capsules**Vocks**$12.45**97 rev5mo ago](https://www.amazon.com/dp/B0GPZLTB3D) [![Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps](https://m.media-amazon.com/images/I/416hBeAHI9L.jpg)**Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps**Nutricost**$11.10**154 rev11mo ago](https://www.amazon.com/dp/B0FNFR1MPT) [![Micro Ingredients L Methylfolate 15mg 240 Softgels | Active 5-MTHF with B6 & Methyl B12 | Methylated Vitamin B9 with Coconut Oil](https://m.media-amazon.com/images/I/41OPLlA1+YL.jpg)**Micro Ingredients L Methylfolate 15mg 240 Softgels | Active 5-MTHF with B6 & Methyl B12 | Methylated Vitamin B9 with Coconut Oil**Micro Ingredients**$28.48**289 rev1y ago](https://www.amazon.com/dp/B0F5S1V6ZQ) [![L Methyl Folate 15mg Plus Methyl B12 Cofactor Organic Berry Flavor High Potency Liquid Sublingual Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms Vitamin B9 & B12 (1oz)](https://m.media-amazon.com/images/I/51ex-pMYOKL.jpg)**L Methyl Folate 15mg Plus Methyl B12 Cofactor Organic Berry Flavor High Potency Liquid Sublingual Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms Vitamin B9 & B12 (1oz)**Triquetra Health**$21.87**5,924 rev4y ago](https://www.amazon.com/dp/B0B83PXLXW)

**~~View all new products →~~**

### **Trending**

90-day click momentum

[![Vocks L Methylfolate 15mg | 5-MTHF + Methyl B12 | High Potency Methylfolate Supplement | Active Methylated Folate Vitamin B9 | MTHFR Supplement| Folate Supplement for Women & Men | 90 Capsules](https://m.media-amazon.com/images/I/41Juex1gneL.jpg)**Vocks L Methylfolate 15mg | 5-MTHF + Methyl B12 | High Potency Methylfolate Supplement | Active Methylated Folate Vitamin B9 | MTHFR Supplement| Folate Supplement for Women & Men | 90 Capsules**Vocks**$12.45**4.5★**▲ 345%**](https://www.amazon.com/dp/B0GPZLTB3D) [![Sports Research 5-MTHF Methyl Folate w/Methylated B12 90 Count Plantgels](https://m.media-amazon.com/images/I/41N-zWwUQuL.jpg)**Sports Research 5-MTHF Methyl Folate w/Methylated B12 90 Count Plantgels**Sports Research**$21.38**4.9★**▲ 337%**](https://www.amazon.com/dp/B0GQXDQHQH) [![Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps](https://m.media-amazon.com/images/I/416hBeAHI9L.jpg)**Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps**Nutricost**$11.10**4.7★**▲ 68%**](https://www.amazon.com/dp/B0FNFR1MPT) [![Micro Ingredients L Methylfolate 15mg 240 Softgels | Active 5-MTHF with B6 & Methyl B12 | Methylated Vitamin B9 with Coconut Oil](https://m.media-amazon.com/images/I/41OPLlA1+YL.jpg)**Micro Ingredients L Methylfolate 15mg 240 Softgels | Active 5-MTHF with B6 & Methyl B12 | Methylated Vitamin B9 with Coconut Oil**Micro Ingredients**$28.48**4.8★**▲ 46%**](https://www.amazon.com/dp/B0F5S1V6ZQ) [![Pure Encapsulations B12 Folate - Energy Supplement to Support Nerves Energy Metabolism & Cognitive Support* - with Vitamin B Folate as Metafolin - 60 Capsules](https://m.media-amazon.com/images/I/41+Q7mKMALL.jpg)**Pure Encapsulations B12 Folate - Energy Supplement to Support Nerves Energy Metabolism & Cognitive Support* - with Vitamin B Folate as Metafolin - 60 Capsules**Pure Encapsulations**$21.25**4.8★**▲ 13%**](https://www.amazon.com/dp/B0058HX9GC)

**~~View all trending →~~**

## **What reviews say buyers love and hate about methylfolate b12**

What buyers praise and complain about, mined from review topics.

### **What buyers love **

**Quality-Overall**16%

*“Quality and ease of use”*

**Vitamin**10%

*“also has essential vitamins”*

**Taste-Overall**9%

*“It tastes pretty good”*

**Energy Level**9%

*“More energy”*

**Focus Enhancement**6%

*“feel like it improves my mood”*

**Advertised Vs Actual Product**6%

*“Just as advertised”*

**Efficiency**6%

*“Very effective”*

**Value For Money**4%

*“Worth Buying”*

**Ease Of Use**3%

*“Easy to use”*

**Dosage**3%

*“Good combination with the doses I needed”*

### **What buyers complain about **

**Dosage**9%

*“This is an extremely high dose. was not aware”*

**Functionality-Overall**7%

*“No results”*

**Taste-Overall**7%

*“It tastes awful”*

**Side Effects**6%

*“Made me sick”*

**Vitamin**5%

*“my vitamin b levels were low”*

**Value For Money**4%

*“The price is a little high”*

**Allergies**4%

*“Allergic”*

**Quality-Overall**4%

*“Its not as good as they make it seem”*

**Sleep Quality**3%

*“I also couldnt sleep”*

**Ingredients-Overall**2%

*“Very disappointed to find this product has xylitol as the first other ingredient”*

### **Top return reasons **

**Dosage**29%

**Advertised Vs Actual Product**14%

**Quality-Overall**7%

**Side Effects**7%

**Product Condition**7%

**Vegan/Organic**7%

**Color**7%

**Value For Money**7%

**Functionality-Overall**7%

**Nutritional Content**4%

## **Common methylfolate b12 questions**

<dl>

<dt>**Is methylfolate b12 profitable to sell on Amazon United States?**</dt><dd>The niche generates $259K/yr across 14 tracked products. 3 of 3 products launched in the last 360 days are still selling. 90-day search growth is -9.6%. Flapen's verdict: Skip it (45/100).</dd>

<dt>**How competitive is the methylfolate b12 niche?**</dt><dd>9 brands and 558 sellers compete. The top 5 products take 75% of clicks and top 5 brands hold 94% of demand.</dd>

<dt>**What do buyers complain about in methylfolate b12?**</dt><dd>Top complaints mined from reviews: Dosage, Functionality-Overall, Taste-Overall. The return rate is 0.0%.</dd>

<dt>**When does demand for methylfolate b12 peak?**</dt><dd>Demand peaks in Jan–Feb–Mar–Sep; the busiest month runs 2.6× the quietest.</dd>

<dt>**What does it cost to enter the methylfolate b12 niche?**</dt><dd>Listings span $8.35–$28.54; the average listing price is $18.67 (sweet spot $15–$100). The average incumbent carries 4,325 reviews — the moat a new listing must climb.</dd>

</dl>

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