---
title: "Lysine Cold Sore Treatment — Amazon US Product Research"
canonical_url: "https://flapen.com/research/us/health-household/lysine-cold-sore-treatment"
last_updated: "2026-08-12T15:14:16.751Z"
locale: en
meta:
description: "Amazon product research for lysine cold sore treatment: demand, competition, pricing, reviews & the verdict. Know if it's worth selling — Flapen."
"og:description": "Amazon product research for lysine cold sore treatment: demand, competition, pricing, reviews & the verdict. Know if it's worth selling — Flapen."
"og:title": "Lysine Cold Sore Treatment — Amazon US Product Research"
---
# **Lysine Cold Sore Treatment**
**Worth a look**
Shows low returns (0.1%), but soft demand (-22.2% this quarter) keeps it on the watch list.
Market size 66Growth 14Conversion 97Competition 23Returns 100Price range 74Avg price 61Brand share 38Review moat 23Quality gap 33
**Returns**
**Incredible****0.1%**
return rate — above 5% kills the launch gate
**Conversion**
**Incredible****15.9%**
search→purchase rate — share of searches ending in a sale
**Price range**
**Good****$6.54–$38.79**
cheapest to priciest tracked listing — scored on the share inside $15–$100
**Market size**
**Good****$649K**
$649K/yr · 308K searches
**Avg price**
**Good****$13.28**
avg listing price — sweet spot $15–$100
**Brand share**
**Okay****82%**
top-5 brand share — brands hold most of the demand
**Quality gap**
**Okay****4.5★**
avg incumbent rating — lower means beatable quality
**Competition**
**Bad****72%**
top-5 click share — a locked-up shelf
**Review moat**
**Bad****7,136.6**
avg incumbent reviews — the moat a new listing must climb
**Growth**
**Bad****-22.2%**
90-day search growth — must beat 0% to launch
## **Is lysine cold sore treatment profitable on Amazon?**
According to Flapen's Amazon United States niche tracking, lysine cold sore treatment is a $649K/yr Amazon United States market (308K searches/yr). The top 5 brands hold 82% of demand. Demand peaks in Jan–Feb–Dec. Verdict: Worth a look — 50/100.
Data updated Jul 11, 2026 · scored weekly · [~~How we score niches ~~](https://flapen.com/research/methodology)
## **lysine cold sore treatment market size & sales**
Units sold, revenue, conversion and listing quality across the tracked shelf.
- **Units sold / yr**
- **50K–60K**
- avg 3,000–4,000/product
- **Revenue / yr**
- **$664K–$797K**
- units × avg price
- **Conversion rate**
- **15.9%**
- **Avg BSR**
- **#161**
- **Page quality**
- **0%**
- **Prime**
- **100%**
- **Sponsored**
- **87%**
- **Out of stock**
- **0.0%**
- **Avg brand age**
- **75 months**
- **Avg seller age**
- **145 days**
## **Competition: brands, sellers & click share**
The top 5 products capture 72% of clicks — a locked-up shelf that new listings rarely crack.
**Brands**
**12 **▲rising
**Sellers**
**562**
**Top-5 brand share**
**82%**
Top 20: 100%
**Top-5 click share**
**72%**
Top 20: 100%
**Open market**
**15%**
- Quantum54% - Basic Organics12% - NOW Foods7% - Herpecin-L5% - Clear Probiotics5% - Basic Brands3% - Open — no brand owns it (6 brands, 15%)
## **lysine cold sore treatment demand & seasonality**
Weekly Amazon search volume, last 104 weeks — -22.2% search growth over the last 90 days.
8K6KPrime Day '25Holiday '25Spike '26 seasonSepDecMarJunAugNovMarMay
Peak months: Jan, Feb, Dec · busiest ÷ quietest = 2.2×
[**Open Trend **](https://flapen.com/research/us/health-household/lysine-cold-sore-treatment/trend)
## **Top lysine cold sore treatment search terms shoppers use**
The exact queries shoppers type, with yearly volume, growth and conversion.
- **lysine cold sore treatment**120K/yr-23.2%15.4% conv. - **lysine lip balm**81K/yr-22.3%14.9% conv. - **lysine chapstick**17K/yr-22.7%13.1% conv. - **cold sore prevention**8K/yr-5.8%7.3% conv. - **lysine lip**8K/yr-25.7%16.1% conv. - **l lysine lip balm**9K/yr-29.1%13.1% conv. - **lysine lip balm cold sore**4K/yr+19.5%1.3% conv. - **lysine cold sore**6K/yr-28.4%16.5% conv. - **lysine lip clear**6K/yr-37.2%21.7% conv. - **lysine for cold sores**9K/yr-33.8%13.2% conv. [**All search terms **](https://flapen.com/research/us/health-household/lysine-cold-sore-treatment/search-terms)
## **Top lysine cold sore treatment products & what they sell for**
Every tracked product — its share of the shelf, its review moat, and what it sells for.
Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.
0%10%$65K20%$130K30%$195K40%$260K1001K10K100K Reviews — right = deep review moatMarket share (90d) ≈ est. sales
Beatable (≤4.3★) Contested Strong incumbent (>4.7★)
All 15 tracked products in this niche — three views at once, no toggling.
### **Top sellers**
by 90-day click share
[1**Quantum Health Lip Clear Lysine+ Cold Sore Treatment Soothe & Moisturize Mouth Sores - L-Lysine Menthol Calendula & Propolis Ointment - Transparent Fever Blister Healing Balm - 0.25 Oz**Quantum**$7.60**4.6★5,884 rev](https://www.amazon.com/dp/B00014EGA0) [2**Basic Brands Lysine Lip Balm Cold Sore & Herpes Simplex Treatment**Basic Organics**$10.74**4.6★4,976 rev](https://www.amazon.com/dp/B000GG0WOC) [3**Quantum Health SuperLysine+ Coldstick Lip Sunscreen - Lysine Herbs & Nutrients Soothe & Moisturize Lips - Softens & Protects from the Sun - SPF 21 - Clear - 0.17 Ounce**Quantum**$7.67**4.6★1,525 rev](https://www.amazon.com/dp/B001CMT8HQ) [4**NOW Foods Supplements (L-Lysine Hydrochloride) 1 000 mg Double Strength Amino Acid 100 Tablets**NOW Foods**$8.52**4.6★37,975 rev](https://www.amazon.com/dp/B000Z9361G) [5**Herpecin-L Everyday Protection Lip Balm Stick SPF 30 - Relief from Cold Sores Fever Blisters and Chapped Lips with Lemon Balm 0.1oz**Herpecin-L**$6.73**4.6★11,909 rev](https://www.amazon.com/dp/B000052YE1)
**~~View all top sellers →~~**
### **Newest**
by launch date
[**Lyranda - Lysine Cold Sore Treatment - Chewable L-Lysine Tablets - Faster Absorption and Better Hygiene**Lyranda**$20.17**757 rev2y ago](https://www.amazon.com/dp/B0D94SZYDF) [**Mederma Cold Sore Discreet Patch - Hydrocolloid Gel Relieves Redness & Swelling Conceals Cold Sores**Mederma**$13.06**12,947 rev5y ago](https://www.amazon.com/dp/B08MVF9YW1) [**Lysine Cold Sore Treatment for Lips with Pre-Probiotics & VIT C | 1 Month Supply | Supercharged Lysine Capsules with Rhamnosus & Acidophilus for Cold Sores Relief Skin + Gut Health & Immune Support**Clear Probiotics**$38.79**778 rev6y ago](https://www.amazon.com/dp/B08881XJNR) [**100% PURE Lysine + Herbs Healing Lip Balm Natural Soothing Nourishment for Sore Cracked Chapped or Irritated Lips - Natural Dry Lip Hydration Therapy for Women & Men**100% PURE**$7.94**636 rev7y ago](https://www.amazon.com/dp/B07FDHKM94) [**Super Lysine Plus+ ColdStick SPF 21 Regular 0.18 oz (Pack of 3) by Quantum Research**Quantum**$20.11**920 rev10y ago](https://www.amazon.com/dp/B01AE5XV5Q)
**~~View all new products →~~**
### **Trending**
90-day click momentum
[**100% PURE Lysine + Herbs Healing Lip Balm Natural Soothing Nourishment for Sore Cracked Chapped or Irritated Lips - Natural Dry Lip Hydration Therapy for Women & Men**100% PURE**$7.94**4.3★**▲ 64%**](https://www.amazon.com/dp/B07FDHKM94) [**Mederma Cold Sore Discreet Patch - Hydrocolloid Gel Relieves Redness & Swelling Conceals Cold Sores**Mederma**$13.06**4.4★**▲ 59%**](https://www.amazon.com/dp/B08MVF9YW1) [**Pure Encapsulations L-Lysine - Essential Amino Acid Supplement for Immune Support & Gum Lip Health* - with L-Lysine HCl - 90 Capsules**Pure Encapsulations**$14.74**4.8★**▲ 29%**](https://www.amazon.com/dp/B000H85JYC) [**NOW Foods Supplements (L-Lysine Hydrochloride) 1 000 mg Double Strength Amino Acid 100 Tablets**NOW Foods**$8.52**4.6★**▲ 20%**](https://www.amazon.com/dp/B000Z9361G) [**Basic Brands Lysine Lip Balm Cold Sore & Herpes Simplex Treatment**Basic Organics**$10.74**4.6★**▲ 19%**](https://www.amazon.com/dp/B000GG0WOC)
**~~View all trending →~~**
## **What reviews say buyers love and hate about lysine cold sore treatment**
What buyers praise and complain about, mined from review topics.
### **What buyers love **
**Quality-Overall**15%
*“Excellent product”*
**Efficiency**11%
*“it works QUICKLY”*
**Cold Relief**10%
*“It prevents cold sores”*
**Value For Money**8%
*“Good value”*
**Pain Relief-Overall**4%
*“No pain at all”*
**Moist/Dry**4%
*“Very effective and moisturizing”*
**Advertised Vs Actual Product**4%
*“Works as advertised”*
**Fever Relief**3%
*“Good for fever blisters”*
**Vitamin**2%
*“Quality vitamins”*
**Soft Feel**2%
*“Creamy and smooth”*
### **What buyers complain about **
**Size-Overall**9%
*“They are larger”*
**Adhesion/Stickiness**7%
*“They're very sticky”*
**Functionality-Overall**7%
*“It didnt help”*
**Taste-Overall**6%
*“Has a weird aftertaste”*
**Pain Relief-Overall**5%
*“more painful then they typically are”*
**Value For Money**4%
*“Waste of money”*
**Allergies**4%
*“I must be allergic”*
**Ease Of Use**4%
*“Very hard to use”*
**Ease Of Chewing/Swallowing**4%
*“Stay away; Impossible to swallow”*
**Moist/Dry**3%
*“started drying out”*
### **Top return reasons **
**Functionality-Overall**17%
**Advertised Vs Actual Product**13%
**Product Condition**10%
**Value For Money**10%
**Smell**9%
**Texture/Consistency-Overall**6%
**Ingredients-Overall**5%
**Certifications**3%
**Leak-Proof**3%
**Adhesion/Stickiness**2%
## **Common lysine cold sore treatment questions**
- **Is lysine cold sore treatment profitable to sell on Amazon United States?**
- The niche generates $649K/yr across 15 tracked products. 90-day search growth is -22.2%. Flapen's verdict: Worth a look (50/100).
- **How competitive is the lysine cold sore treatment niche?**
- 12 brands and 562 sellers compete. The top 5 products take 72% of clicks and top 5 brands hold 82% of demand.
- **What do buyers complain about in lysine cold sore treatment?**
- Top complaints mined from reviews: Size-Overall, Adhesion/Stickiness, Functionality-Overall. The return rate is 0.1%.
- **When does demand for lysine cold sore treatment peak?**
- Demand peaks in Jan–Feb–Dec; the busiest month runs 2.2× the quietest.
- **What does it cost to enter the lysine cold sore treatment niche?**
- Listings span $6.54–$38.79; the average listing price is $13.28 (sweet spot $15–$100). The average incumbent carries 7,137 reviews — the moat a new listing must climb.
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