---
title: "Headache Medicine — $49K/mo Amazon US Product Research"
canonical_url: "https://flapen.com/research/us/health-household/headache-medicine"
last_updated: "2026-08-12T04:30:13.783Z"
locale: en
meta:
description: "Amazon product research for headache medicine: $49K/mo market, demand, competition, pricing, reviews & the verdict. Know if it's worth selling — Flapen."
"og:description": "Amazon product research for headache medicine: $49K/mo market, demand, competition, pricing, reviews & the verdict. Know if it's worth selling — Flapen."
"og:title": "Headache Medicine — $49K/mo Amazon US Product Research"
---
# **Headache Medicine**
**Skip it**
Brand-locked demand (top 5 brands take 100% of clicks) — this niche doesn't clear our bar today.
Market size 63Growth 25Conversion 99Competition 14Returns 100Price range 28Avg price 54Brand share 0Review moat 25Quality gap 16
**Returns**
**Incredible****0.0%**
return rate — above 5% kills the launch gate
**Conversion**
**Incredible****17.9%**
search→purchase rate — share of searches ending in a sale
**Market size**
**Good****$583K**
$583K/yr · 261K searches
**Avg price**
**Good****$12.46**
avg listing price — sweet spot $15–$100
**Price range**
**Okay****$4.89–$18.93**
cheapest to priciest tracked listing — scored on the share inside $15–$100
**Growth**
**Okay****+0.2%**
90-day search growth — must beat 0% to launch
**Review moat**
**Bad****4,493.56**
avg incumbent reviews — the moat a new listing must climb
**Quality gap**
**Bad****4.7★**
avg incumbent rating — lower means beatable quality
**Competition**
**Bad****83%**
top-5 click share — a locked-up shelf
**Brand share**
**Bad****100%**
top-5 brand share — brand-locked demand
## **Is headache medicine profitable on Amazon?**
According to Flapen's Amazon United States niche tracking, headache medicine is a $583K/yr Amazon United States market (261K searches/yr). The top 5 brands hold 100% of demand. Demand peaks in Jun–Jul–Aug. Verdict: Skip it — 42/100.
Data updated Jul 11, 2026 · scored weekly · [~~How we score niches ~~](https://flapen.com/research/methodology)
## **headache medicine market size & sales**
Units sold, revenue, conversion and listing quality across the tracked shelf.
- **Units sold / yr**
- **40K–50K**
- avg 5,000–6,000/product
- **Revenue / yr**
- **$498K–$623K**
- units × avg price
- **Conversion rate**
- **17.9%**
- **Avg BSR**
- **#138**
- **Page quality**
- **0%**
- **Prime**
- **100%**
- **Sponsored**
- **89%**
- **Out of stock**
- **0.0%**
- **Avg brand age**
- **86 months**
- **Avg seller age**
- **153 days**
## **Competition: brands, sellers & click share**
The top 5 products capture 83% of clicks — a locked-up shelf that new listings rarely crack.
**Brands**
**5 **—flat
**Sellers**
**65**
**Top-5 brand share**
**100%**
Top 20: 100%
**Top-5 click share**
**83%**
Top 20: 100%
**Open market**
**0%**
- Excedrin79% - GenCare9% - Amazon Basic Care5% - RIGHT REMEDIES4% - TIME-CAP LABS, INC.3%
## **headache medicine demand & seasonality**
Weekly Amazon search volume, last 104 weeks — +0.2% search growth over the last 90 days.
8K6KSpike '24Spike '25Prime Day '25Spike '26 seasonSepDecMarJunAugNovMarMay
Peak months: Jun, Jul, Aug · busiest ÷ quietest = 2.0×
[**Open Trend **](https://flapen.com/research/us/health-household/headache-medicine/trend)
## **Top headache medicine search terms shoppers use**
The exact queries shoppers type, with yearly volume, growth and conversion.
- **excedrin extra strength**185K/yr-1.1%21.0% conv. - **extra strength excedrin**18K/yr-0.4%18.1% conv. - **headache relief pills**13K/yr+5.4%4.1% conv. - **headache pills**10K/yr+41.9%5.9% conv. - **excedrin extra strength headache**5K/yr+154.2%16.6% conv. - **pastillas para dolor de cabeza**7K/yr-5.6%0.5% conv. - **pastillas para el dolor de cabeza**6K/yr-13.7%0.5% conv. - **head pain**4K/yr+16.4%0.0% conv. - **equate headache relief**4K/yr+20.7%4.3% conv. - **excedrin extra strength 300 count**4K/yr-21.4%11.8% conv. [**All search terms **](https://flapen.com/research/us/health-household/headache-medicine/search-terms)
## **Top headache medicine products & what they sell for**
Every tracked product — its share of the shelf, its review moat, and what it sells for.
Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.
0%15%$87K30%$175K45%$262K60%$350K1001K10K100K Reviews — right = deep review moatMarket share (90d) ≈ est. sales
Beatable (≤4.3★) Contested Strong incumbent (>4.7★)
All 9 tracked products in this niche — three views at once, no toggling.
### **Top sellers**
by 90-day click share
[1**Excedrin Extra Strength Pain Relief Caplets for Headache Relief Acetaminophen 250mg Aspirin 250mg Caffeine 65mg Pain Reliever 200 Count**Excedrin**$18.93**4.8★8,774 rev](https://www.amazon.com/dp/B012SA8IOO) [2**Excedrin Extra Strength Pain Relief Caplets Headache Relief 100 Count**Excedrin**$12.19**4.8★2,771 rev](https://www.amazon.com/dp/B01CRE8VO8) [3**GenCare - Headache Relief Acetaminophen with Aspirin (NSAID) & Caffeine (300 Caplets) Value Pack | Head Pain Muscle Aches Back Pain & Body | Generic ExcedrEn Extra Strength**GenCare**$13.88**4.7★7,776 rev](https://www.amazon.com/dp/B086S1VRZQ) [4**Excedrin Extra Strength Caplets for Headache Pain Relief Acetaminophen 250mg Aspirin 250mg Caffeine 65mg Pain Reliever 24 count**Excedrin**$4.89**4.8★3,262 rev](https://www.amazon.com/dp/B001AS81U2) [5**Excedrin Migraine Relief Caplets to Alleviate Migraine Symptoms - 200 Count**Excedrin**$18.89**4.9★14,121 rev](https://www.amazon.com/dp/B01341NLE8)
**~~View all top sellers →~~**
### **Newest**
by launch date
[**Excedrin Rapid Relief Caplets 500mg Acetaminophen Fast Pain Relief in 15 Minutes 160 Count**Excedrin**$16.13**117 rev3mo ago](https://www.amazon.com/dp/B0DQYNNL6Y) [**RIGHT REMEDIES Extra Strength Headache Relief with Acetaminophen Aspirin (NSAID) & Caffeine (300 caplets) Back & Body Pain Relief Compare to the Active Ingredients in Excedrin Extra Strength**RIGHT REMEDIES**$10.59**249 rev1y ago](https://www.amazon.com/dp/B0DP5G2HFG) [**TIME-Cap Labs Extra Strength Acetaminophen 250mg with Aspirin 250mg & Caffeine 65mg Caplets - Pain Reliever/Fever Reducer for Headache Relief Muscle Aches & Body Pain (300 Count)**TIME-CAP LABS, INC.**$10.13**1,639 rev2y ago](https://www.amazon.com/dp/B0CV5SXTXD) [**Amazon Basic Care Extra Strength Headache Relief Geltabs Pain Reliever for Arthritis Menstrual Pain and Cramps 80 Count**Amazon Basic Care**$6.52**1,733 rev4y ago](https://www.amazon.com/dp/B094NWNC2N) [**GenCare - Headache Relief Acetaminophen with Aspirin (NSAID) & Caffeine (300 Caplets) Value Pack | Head Pain Muscle Aches Back Pain & Body | Generic ExcedrEn Extra Strength**GenCare**$13.88**7,776 rev6y ago](https://www.amazon.com/dp/B086S1VRZQ)
**~~View all new products →~~**
### **Trending**
90-day click momentum
[**Excedrin Rapid Relief Caplets 500mg Acetaminophen Fast Pain Relief in 15 Minutes 160 Count**Excedrin**$16.13**4.5★**▲ 243%**](https://www.amazon.com/dp/B0DQYNNL6Y) [**TIME-Cap Labs Extra Strength Acetaminophen 250mg with Aspirin 250mg & Caffeine 65mg Caplets - Pain Reliever/Fever Reducer for Headache Relief Muscle Aches & Body Pain (300 Count)**TIME-CAP LABS, INC.**$10.13**4.8★**▲ 162%**](https://www.amazon.com/dp/B0CV5SXTXD) [**RIGHT REMEDIES Extra Strength Headache Relief with Acetaminophen Aspirin (NSAID) & Caffeine (300 caplets) Back & Body Pain Relief Compare to the Active Ingredients in Excedrin Extra Strength**RIGHT REMEDIES**$10.59**4.7★**▲ 79%**](https://www.amazon.com/dp/B0DP5G2HFG) [**Amazon Basic Care Extra Strength Headache Relief Geltabs Pain Reliever for Arthritis Menstrual Pain and Cramps 80 Count**Amazon Basic Care**$6.52**4.7★**▲ 13%**](https://www.amazon.com/dp/B094NWNC2N) [**Excedrin Extra Strength Pain Relief Caplets for Headache Relief Acetaminophen 250mg Aspirin 250mg Caffeine 65mg Pain Reliever 200 Count**Excedrin**$18.93**4.8★**— 3%**](https://www.amazon.com/dp/B012SA8IOO)
**~~View all trending →~~**
## **What reviews say buyers love and hate about headache medicine**
What buyers praise and complain about, mined from review topics.
### **What buyers love **
**Value For Money**22%
*“Great Value”*
**Quality-Overall**20%
*“Amazon delivers on this value of quality aspirin”*
**Efficiency**14%
*“Effective”*
**Advertised Vs Actual Product**11%
*“As Described”*
**Ease Of Chewing/Swallowing**4%
*“The caplets are easy to take”*
**Ingredients-Overall**4%
*“Exact same ingredients as Excedrin”*
**Strength**2%
*“Effective”*
**Ease Of Use**2%
*“The caplets are easy to take”*
**Dosage**2%
*“the bottle contains a large quantity which makes it convenient to keep on hand”*
**Side Effects**2%
*“I always keep a bottle of Excedrin on hand because it has honestly been a lifesaver when headaches hit”*
### **What buyers complain about **
**Functionality-Overall**20%
*“is no longer effective”*
**Smell**10%
*“Horrible smell”*
**Dosage**6%
*“I had to stop taken ibuprofen”*
**Ease Of Chewing/Swallowing**5%
*“As soon as I feel one coming on I chew one up so that it goes through my stomach walls quickly”*
**Acid Regulator/Stomach Ache Relief**4%
*“can cause stomach upset”*
**Size-Overall**3%
*“Much larger than I've seen before”*
**Side Effects**3%
*“Excedrin CAUSED my migraines”*
**Pain Relief-Overall**3%
*“it simply didnt provide the relief I was hoping for”*
**Advertised Vs Actual Product**2%
*“Doesnt look right”*
**Taste-Overall**2%
*“Terrible Taste”*
## **Common headache medicine questions**
- **Is headache medicine profitable to sell on Amazon United States?**
- The niche generates $583K/yr across 9 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is +0.2%. Flapen's verdict: Skip it (42/100).
- **How competitive is the headache medicine niche?**
- 5 brands and 65 sellers compete. The top 5 products take 83% of clicks and top 5 brands hold 100% of demand.
- **What do buyers complain about in headache medicine?**
- Top complaints mined from reviews: Functionality-Overall, Smell, Dosage. The return rate is 0.0%.
- **When does demand for headache medicine peak?**
- Demand peaks in Jun–Jul–Aug; the busiest month runs 2.0× the quietest.
- **What does it cost to enter the headache medicine niche?**
- Listings span $4.89–$18.93; the average listing price is $12.46 (sweet spot $15–$100). The average incumbent carries 4,494 reviews — the moat a new listing must climb.
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