---
title: "B6 B12 Folic Acid Supplement — $60K/yr Amazon US Niche (2026) - Flapen"
canonical_url: "https://flapen.com/research/us/health-household/b6-b12-folic-acid-supplement"
last_updated: "2026-08-09T16:28:07.889Z"
locale: en
meta:
  description: "Niche score 49/100 · $60K/yr market · 48K searches/yr · $14.72 avg price. Doesn't clear our bar today. Data updated Jul 2026."
  "og:description": "Niche score 49/100 · $60K/yr market · 48K searches/yr · $14.72 avg price. Doesn't clear our bar today. Data updated Jul 2026."
  "og:title": "B6 B12 Folic Acid Supplement — $60K/yr Amazon US Niche (2026) - Flapen"
---

# **b6 b12 folic acid supplement**

**Skip it**

A small market ($60K/yr) — this niche doesn't clear our bar today.

Market size 15Growth 25Conversion 81Competition 51Returns 100Price range 58Avg price 73Brand share 76Review moat 22Quality gap 22

**Returns**

**Incredible****0.0%**

return rate — above 5% kills the launch gate

**Conversion**

**Great****8.4%**

search→purchase rate — share of searches ending in a sale

**Brand share**

**Great****59%**

top-5 brand share — no brand owns this niche

**Avg price**

**Good****$14.72**

avg listing price — sweet spot $15–$100

**Price range**

**Good****$5.18–$28.54**

cheapest to priciest tracked listing — scored on the share inside $15–$100

**Competition**

**Good****55%**

top-5 click share — leaders hold, buyers still browse

**Growth**

**Bad****-0.1%**

90-day search growth — must beat 0% to launch

**Quality gap**

**Bad****4.7★**

avg incumbent rating — lower means beatable quality

**Review moat**

**Bad****9,477.46**

avg incumbent reviews — the moat a new listing must climb

**Market size**

**Bad****$60K**

$60K/yr · 48K searches

**Signals**[** No Dominant Brand**](https://flapen.com/research/niches?market=us&signal=no_dominant_brand "Top brand's click share < 20%")

According to Flapen's Amazon United States niche tracking, b6 b12 folic acid supplement is a $60K/yr Amazon United States market (48K searches/yr). The top 5 brands hold 59% of demand. Demand peaks in Apr–Aug–Sep. Verdict: Skip it — 49/100.

Data updated Jul 28, 2026 · scored weekly · [~~How we score niches ~~](https://flapen.com/research/methodology)

## **b6 b12 folic acid supplement market data**

<dl>

<dt>**Units sold / yr**</dt><dd>**4K–5K**</dd><dd>avg 100–250/product</dd>

<dt>**Revenue / yr**</dt><dd>**$59K–$74K**</dd><dd>units × avg price</dd>

<dt>**Conversion rate**</dt><dd>**8.4%**</dd>

<dt>**Avg BSR**</dt><dd>**#274**</dd>

<dt>**Page quality**</dt><dd>**0%**</dd>

<dt>**Prime**</dt><dd>**100%**</dd>

<dt>**Sponsored**</dt><dd>**79%**</dd>

<dt>**Out of stock**</dt><dd>**0.0%**</dd>

<dt>**Avg brand age**</dt><dd>**100 months**</dd>

<dt>**Avg seller age**</dt><dd>**154 days**</dd>

</dl>

## **Competition & brand share**

The top 5 products take 55% of clicks — established leaders, but buyers still shop beyond them.

**Brands**

**18 **—flat

**Sellers**

**621**

**Top-5 brand share**

**59%**

Top 20: 100%

**Top-5 click share**

**55%**

Top 20: 96%

**Open market**

**33%**

- Vitamatic17% - Life Extension16% - Jarrow Formulas10% - Pure Encapsulations9% - NOW Foods8% - Triquetra Health8%

## **Demand & seasonality**

Weekly Amazon search volume, last 104 weeks — -0.1% search growth over the last 90 days.

4K3KSpike '25Prime Day '25 seasonSepDecMarJunAugNovMarMay

Peak months: Apr, Aug, Sep · busiest ÷ quietest = 3.2×

[**Open Trend **](https://flapen.com/research/us/health-household/b6-b12-folic-acid-supplement/trend)

## **Top b6 b12 folic acid supplement search terms**

- **b9 and b12 vitamin folic acid**13K/yr-0.1%6.3% conv. - **b12 with folic acid**7K/yr-15.1%7.5% conv. - **b12 and folic acid supplement**4K/yr+12.2%9.2% conv. - **vitamin b12 with folic acid**4K/yr+9.8%7.8% conv. - **vitamin b12 and folic acid**4K/yr+17.1%6.0% conv. - **vitamin b9 and b12**3K/yr+39.0%5.3% conv. - **b12 folic acid**3K/yr+19.8%8.0% conv. - **b12 folic acid supplement**4K/yr-29.0%9.7% conv. - **folic acid b12**3K/yr+12.2%8.4% conv. - **folic acid and b12 supplement**3K/yr-24.3%8.9% conv. [**All search terms **](https://flapen.com/research/us/health-household/b6-b12-folic-acid-supplement/search-terms)

## **Top b6 b12 folic acid supplement products on Amazon**

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

0%5%$3K10%$6K15%$9K20%$12K101001K10K100K Reviews — right = deep review moatMarket share (90d) ≈ est. sales

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 24 tracked products in this niche — three views at once, no toggling.

### **Top sellers**

by 90-day click share

[1![Vitamatic Folic Acid Vitamin B12 & B6 180 Fast Dissolve Tablets Heart Health Energy Production & Red Blood Cell Support](https://m.media-amazon.com/images/I/415QlZvOerL.jpg)**Vitamatic Folic Acid Vitamin B12 & B6 180 Fast Dissolve Tablets Heart Health Energy Production & Red Blood Cell Support**Vitamatic**$9.92**4.7★1,489 rev](https://www.amazon.com/dp/B0C6LNHFD9) [2![Life Extension BioActive Folate & Vitamin B12 Promotes Heart Brain & GI Tract Health Non-GMO Gluten-Free Vegetarian 90 Capsules](https://m.media-amazon.com/images/I/41Sec8lrL3L.jpg)**Life Extension BioActive Folate & Vitamin B12 Promotes Heart Brain & GI Tract Health Non-GMO Gluten-Free Vegetarian 90 Capsules**Life Extension**$8.35**4.7★3,684 rev](https://www.amazon.com/dp/B019YGJLNM) [3![Pure Encapsulations B12 Folate - Energy Supplement to Support Nerves Energy Metabolism & Cognitive Support* - with Vitamin B Folate as Metafolin - 60 Capsules](https://m.media-amazon.com/images/I/41+Q7mKMALL.jpg)**Pure Encapsulations B12 Folate - Energy Supplement to Support Nerves Energy Metabolism & Cognitive Support* - with Vitamin B Folate as Metafolin - 60 Capsules**Pure Encapsulations**$21.25**4.8★3,407 rev](https://www.amazon.com/dp/B0058HX9GC) [4![NOW Supplements Folic Acid 800 mcg + B-12 (Cyanocobalamin) 25 mcg B Complex Vitamin 250 Tablets](https://m.media-amazon.com/images/I/41N9We0WCYL.jpg)**NOW Supplements Folic Acid 800 mcg + B-12 (Cyanocobalamin) 25 mcg B Complex Vitamin 250 Tablets**NOW Foods**$5.79**4.7★3,036 rev](https://www.amazon.com/dp/B0009U84Z4) [5![Natures Bounty Super B Complex Vitamins with Vitamin C & Folic Acid Vitamins for Immune & Cellular Energy Support 150 Tablets](https://m.media-amazon.com/images/I/41Al6x+mTKL.jpg)**Natures Bounty Super B Complex Vitamins with Vitamin C & Folic Acid Vitamins for Immune & Cellular Energy Support 150 Tablets**Nature's Bounty**$10.28**4.7★60,067 rev](https://www.amazon.com/dp/B0014D2GEK)

**~~View all top sellers →~~**

### **Newest**

by launch date

[![Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps](https://m.media-amazon.com/images/I/416hBeAHI9L.jpg)**Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps**Nutricost**$11.10**154 rev11mo ago](https://www.amazon.com/dp/B0FNFR1MPT) [![Bronson Super B Vitamin B Complex Sustained Release for Energy 60 Tablets](https://m.media-amazon.com/images/I/41QCXmj1SIL.jpg)**Bronson Super B Vitamin B Complex Sustained Release for Energy 60 Tablets**Bronson**$10.00**9,428 rev2y ago](https://www.amazon.com/dp/B0CT5Y3XK2) [![USDA Organic Vitamin B-Complex 20000mcg - B5 B12 B1 B6 B7 B9 B3 - 2Oz](https://m.media-amazon.com/images/I/516Zr5UeMXL.jpg)**USDA Organic Vitamin B-Complex 20000mcg - B5 B12 B1 B6 B7 B9 B3 - 2Oz**NUTRAHARMONY**$22.51**7,709 rev2y ago](https://www.amazon.com/dp/B0CKT5PGPN) [![NatureWise Vitamin B Complex for Women and Men - with Folic Acid Biotin B1 B2 B3 B6 B12 - Support Cellular Energy & Mental Clarity - Gluten & Dairy Free - 60 Softgels[2-Month Supply]](https://m.media-amazon.com/images/I/41OeDJKrNhL.jpg)**NatureWise Vitamin B Complex for Women and Men - with Folic Acid Biotin B1 B2 B3 B6 B12 - Support Cellular Energy & Mental Clarity - Gluten & Dairy Free - 60 Softgels\[2-Month Supply\]**NatureWise**$5.70**5,255 rev2y ago](https://www.amazon.com/dp/B0CHKVFDVN) [![Vitamatic Folic Acid Vitamin B12 & B6 180 Fast Dissolve Tablets Heart Health Energy Production & Red Blood Cell Support](https://m.media-amazon.com/images/I/415QlZvOerL.jpg)**Vitamatic Folic Acid Vitamin B12 & B6 180 Fast Dissolve Tablets Heart Health Energy Production & Red Blood Cell Support**Vitamatic**$9.92**1,489 rev3y ago](https://www.amazon.com/dp/B0C6LNHFD9)

**~~View all new products →~~**

### **Trending**

90-day click momentum

[![Metagenics Intrinsi Vitamin B12-Folate - with Methylcobalamin L-5-MTHF & Intrinsic Factor - Supports Energy Metabolism Nervous System & Heart Health - Non-GMO & Gluten-Free - 60 Tablets](https://m.media-amazon.com/images/I/41f3Nz3kHtL.jpg)**Metagenics Intrinsi Vitamin B12-Folate - with Methylcobalamin L-5-MTHF & Intrinsic Factor - Supports Energy Metabolism Nervous System & Heart Health - Non-GMO & Gluten-Free - 60 Tablets**Metagenics**$25.83**4.7★**▲ 100%**](https://www.amazon.com/dp/B002HSM2IG) [![Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps](https://m.media-amazon.com/images/I/416hBeAHI9L.jpg)**Nutricost Methylated Vitamin B12 + Folate Supplement (2 000 mcg) 120 Caps**Nutricost**$11.10**4.7★**▲ 94%**](https://www.amazon.com/dp/B0FNFR1MPT) [![Jarrow Formulas Methyl B-12 & Methyl Folate Bioactive Vitamin B9 and Vitamin B12 Supplement Supports Cellular Energy Production Healthy Brain Function & Metabolism 60 Chewable Tablets 60 Servings](https://m.media-amazon.com/images/I/41QeoWNZozL.jpg)**Jarrow Formulas Methyl B-12 & Methyl Folate Bioactive Vitamin B9 and Vitamin B12 Supplement Supports Cellular Energy Production Healthy Brain Function & Metabolism 60 Chewable Tablets 60 Servings**Jarrow Formulas**$28.54**4.7★**▲ 66%**](https://www.amazon.com/dp/B00OGXIGOE) [![L Methyl Folate 15mg Plus Methyl B12 Cofactor High Potency Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms of Vitamin B9 & B12 (60 Capsules 60 Servings)](https://m.media-amazon.com/images/I/51RcsVNnQ7L.jpg)**L Methyl Folate 15mg Plus Methyl B12 Cofactor High Potency Active 5-MTHF Form - Supports Mood Methylation Cognition Bioactive Forms of Vitamin B9 & B12 (60 Capsules 60 Servings)**Triquetra Health**$21.67**4.6★**▲ 56%**](https://www.amazon.com/dp/B0938NKV1G) [![Jarrow Formulas Methyl B-12 & Methyl Folate Bioactive Vitamin B9 & Vitamin B12 Supplement Supports Cellular Energy Production Healthy Brain Function & Metabolism 100 Chewable Tablets 100 Servings](https://m.media-amazon.com/images/I/41i17O3xpgL.jpg)**Jarrow Formulas Methyl B-12 & Methyl Folate Bioactive Vitamin B9 & Vitamin B12 Supplement Supports Cellular Energy Production Healthy Brain Function & Metabolism 100 Chewable Tablets 100 Servings**Jarrow Formulas**$13.68**4.6★**▲ 38%**](https://www.amazon.com/dp/B01IJR5VM2)

**~~View all trending →~~**

## **What buyers say about b6 b12 folic acid supplement**

What buyers praise and complain about, mined from review topics.

### **What buyers love **

**Quality-Overall**16%

*“Great price for a quality product”*

**Vitamin**14%

*“Good quality vitamins”*

**Energy Level**10%

*“Good energy”*

**Taste-Overall**7%

*“Doesnt taste as badly as it could”*

**Value For Money**7%

*“Great deal”*

**Advertised Vs Actual Product**5%

*“As advertised”*

**Efficiency**4%

*“seems effective”*

**Focus Enhancement**4%

*“my mood has improved”*

**Ease Of Use**3%

*“Ease of use”*

**Ease Of Chewing/Swallowing**2%

*“These are chewable”*

### **What buyers complain about **

**Taste-Overall**17%

*“Most disgusting taste ever”*

**Smell**9%

*“Absolutely disgusting smell”*

**Dosage**6%

*“Dosage is too high”*

**Vitamin**6%

*“Sometimes our way of living doesnt give us all the vitamins we need”*

**Side Effects**4%

*“Side effects”*

**Functionality-Overall**4%

*“Not effective”*

**Value For Money**3%

*“The price is a little high”*

**Quality-Overall**3%

*“There dont seem to be any quality control”*

**Energy Level**3%

*“Energy level did not change at all”*

**Ingredients-Overall**2%

*“Cheap formula”*

### **Top return reasons **

**Vitamin**18%

**Dosage**15%

**Functionality-Overall**9%

**Advertised Vs Actual Product**8%

**Taste-Overall**6%

**Ease Of Use**6%

**Side Effects**6%

**Smell**6%

**Product Condition**3%

**Charging**3%

## **Common questions**

<dl>

<dt>**Is b6 b12 folic acid supplement profitable to sell on Amazon United States?**</dt><dd>The niche generates $60K/yr across 24 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is -0.1%. Flapen's verdict: Skip it (49/100).</dd>

<dt>**How competitive is the b6 b12 folic acid supplement niche?**</dt><dd>18 brands and 621 sellers compete. The top 5 products take 55% of clicks and top 5 brands hold 59% of demand.</dd>

<dt>**What do buyers complain about in b6 b12 folic acid supplement?**</dt><dd>Top complaints mined from reviews: Taste-Overall, Smell, Dosage. The return rate is 0.0%.</dd>

<dt>**When does demand for b6 b12 folic acid supplement peak?**</dt><dd>Demand peaks in Apr–Aug–Sep; the busiest month runs 3.2× the quietest.</dd>

<dt>**What does it cost to enter the b6 b12 folic acid supplement niche?**</dt><dd>Listings span $5.18–$28.54; the average listing price is $14.72 (sweet spot $15–$100). The average incumbent carries 9,477 reviews — the moat a new listing must climb.</dd>

</dl>

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