---
title: "Acetaminophen 500mg — $260K/yr Amazon US Niche (2026) - Flapen"
canonical_url: "https://flapen.com/research/us/health-household/acetaminophen-500mg"
last_updated: "2026-08-09T03:50:17.159Z"
locale: en
meta:
  description: "Niche score 43/100 · $260K/yr market · 163K searches/yr · $12.65 avg price. Doesn't clear our bar today. Data updated Jul 2026."
  "og:description": "Niche score 43/100 · $260K/yr market · 163K searches/yr · $12.65 avg price. Doesn't clear our bar today. Data updated Jul 2026."
  "og:title": "Acetaminophen 500mg — $260K/yr Amazon US Niche (2026) - Flapen"
---

# **acetaminophen 500mg**

**Skip it**

A deep review moat (35,444 avg reviews) — this niche doesn't clear our bar today.

Market size 48Growth 21Conversion 95Competition 24Returns 100Price range 57Avg price 55Brand share 17Review moat 8Quality gap 14

**Returns**

**Incredible****0.0%**

return rate — above 5% kills the launch gate

**Conversion**

**Incredible****12.6%**

search→purchase rate — share of searches ending in a sale

**Price range**

**Good****$3.26–$30.70**

cheapest to priciest tracked listing — scored on the share inside $15–$100

**Avg price**

**Good****$12.65**

avg listing price — sweet spot $15–$100

**Market size**

**Okay****$260K**

$260K/yr · 163K searches

**Competition**

**Bad****71%**

top-5 click share — a locked-up shelf

**Growth**

**Bad****-8.0%**

90-day search growth — must beat 0% to launch

**Brand share**

**Bad****93%**

top-5 brand share — brand-locked demand

**Quality gap**

**Bad****4.8★**

avg incumbent rating — lower means beatable quality

**Review moat**

**Bad****35,444.25**

avg incumbent reviews — the moat a new listing must climb

According to Flapen's Amazon United States niche tracking, acetaminophen 500mg is a $260K/yr Amazon United States market (163K searches/yr). The top 5 brands hold 93% of demand. Demand peaks in Sep–Oct. Verdict: Skip it — 43/100.

Data updated Jul 11, 2026 · scored weekly · [~~How we score niches ~~](https://flapen.com/research/methodology)

## **acetaminophen 500mg market data**

<dl>

<dt>**Units sold / yr**</dt><dd>**20K–25K**</dd><dd>avg 1,250–1,500/product</dd>

<dt>**Revenue / yr**</dt><dd>**$253K–$316K**</dd><dd>units × avg price</dd>

<dt>**Conversion rate**</dt><dd>**12.6%**</dd>

<dt>**Avg BSR**</dt><dd>**#81**</dd>

<dt>**Page quality**</dt><dd>**0%**</dd>

<dt>**Prime**</dt><dd>**88%**</dd>

<dt>**Sponsored**</dt><dd>**100%**</dd>

<dt>**Out of stock**</dt><dd>**0.0%**</dd>

<dt>**Avg brand age**</dt><dd>**98 months**</dd>

<dt>**Avg seller age**</dt><dd>**156 days**</dd>

</dl>

## **Competition & brand share**

The top 5 products capture 71% of clicks — a locked-up shelf that new listings rarely crack.

**Brands**

**8 **▲rising

**Sellers**

**75**

**Top-5 brand share**

**93%**

Top 20: 100%

**Top-5 click share**

**71%**

Top 20: 100%

**Open market**

**4%**

- Amazon Basic Care61% - Belmora paracetamol18% - HealthA2Z5% - Tylenol5% - Generic4% - GoodMeds3% - Open — no brand owns it (2 brands, 4%)

## **Demand & seasonality**

Weekly Amazon search volume, last 104 weeks — -8.0% search growth over the last 90 days.

40K30KSpike '24Prime Day '25Spike '25 seasonSepDecMarJunAugNovMarMay

Peak months: Sep, Oct · busiest ÷ quietest = 2.6×

[**Open Trend **](https://flapen.com/research/us/health-household/acetaminophen-500mg/trend)

## **Top acetaminophen 500mg search terms**

- **paracetamol 500mg tablets for adults**68K/yr-26.7%6.2% conv. - **generic tylenol**17K/yr+6.9%19.0% conv. - **generic tylenol extra strength 500mg**6K/yr+130.8%21.3% conv. - **paracetamol 1000mg**19K/yr-25.9%3.4% conv. - **amazon acetaminophen 500mg extra strength**10K/yr+13.8%22.2% conv. - **kirkland acetaminophen 500mg extra strength**7K/yr+43.2%6.0% conv. - **acetomenaphen extra strength 500mg generic amazon 500 caplets**9K/yr-35.5%23.9% conv. - **equate acetaminophen 500mg extra strength**6K/yr+1.4%9.4% conv. - **equate pain reliever 500mg**6K/yr-14.0%8.5% conv. - **equate pain reliever**5K/yr+27.4%4.7% conv. [**All search terms **](https://flapen.com/research/us/health-household/acetaminophen-500mg/search-terms)

## **Top acetaminophen 500mg products on Amazon**

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

0%5%$13K10%$26K15%$39K20%$52K1001K10K100K Reviews — right = deep review moatMarket share (90d) ≈ est. sales

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 16 tracked products in this niche — three views at once, no toggling.

### **Top sellers**

by 90-day click share

[1![Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever/Fever Reducer 500 Count](https://m.media-amazon.com/images/I/41E9F7nBirL.jpg)**Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever/Fever Reducer 500 Count**Amazon Basic Care**$8.50**4.8★90,285 rev](https://www.amazon.com/dp/B074F2TF79) [2![Belmora Paracetamol Acetaminophen 325mg 20 Softgels for Pain Relief Liquid Filled Capsules for Rapid Release Fever Reducer for Adults Extra Strength](https://m.media-amazon.com/images/I/41vUVanC+UL.jpg)**Belmora Paracetamol Acetaminophen 325mg 20 Softgels for Pain Relief Liquid Filled Capsules for Rapid Release Fever Reducer for Adults Extra Strength**Belmora paracetamol**$8.16**4.6★788 rev](https://www.amazon.com/dp/B0C6B7D1F2) [3![Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg 200 Count](https://m.media-amazon.com/images/I/41pFWlHrCGL.jpg)**Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg 200 Count**Amazon Basic Care**$5.33**4.8★90,285 rev](https://www.amazon.com/dp/B074F2H9VT) [4![Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever and Fever Reducer for Headache Backache Arthritis Pain Menstrual Cramps 1000 Count (Packaging may vary)](https://m.media-amazon.com/images/I/41aWe6DCfPL.jpg)**Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever and Fever Reducer for Headache Backache Arthritis Pain Menstrual Cramps 1000 Count (Packaging may vary)**Amazon Basic Care**$14.29**4.8★90,285 rev](https://www.amazon.com/dp/B083WC1R4Y) [5![Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever/Fever Reducer 100 Count](https://m.media-amazon.com/images/I/413HC6tF6nL.jpg)**Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever/Fever Reducer 100 Count**Amazon Basic Care**$3.26**4.8★90,285 rev](https://www.amazon.com/dp/B096Y26LYD)

**~~View all top sellers →~~**

### **Newest**

by launch date

[![GoodMeds Compare to Extra Strength Tylenol | Acetaminophen 500mg Extra Strength Pain Reliever & Fever Reducer | Headache Muscle Aches Back Pain Cold & Flu Relief 500 Count](https://m.media-amazon.com/images/I/41sWH-WMLcL.jpg)**GoodMeds Compare to Extra Strength Tylenol | Acetaminophen 500mg Extra Strength Pain Reliever & Fever Reducer | Headache Muscle Aches Back Pain Cold & Flu Relief 500 Count**GoodMeds**$9.81**403 rev8mo ago](https://www.amazon.com/dp/B0FZNCQYMH) [![Extra Strength Acetaminophen 500mg Gelcaps - 225 Count (Pack of 1)](https://m.media-amazon.com/images/I/41nz8xBKu3L.jpg)**Extra Strength Acetaminophen 500mg Gelcaps - 225 Count (Pack of 1)**Generic**$23.14**162 rev1y ago](https://www.amazon.com/dp/B0F91N65K3) [![Acetaminophen 500mg Extra Strength Rapid Release 400 Gelcaps](https://m.media-amazon.com/images/I/51w6SFptpVL.jpg)**Acetaminophen 500mg Extra Strength Rapid Release 400 Gelcaps**Generic**$30.70**129 rev1y ago](https://www.amazon.com/dp/B0F6YSGTLL) [![Belmora Paracetamol Acetaminophen 325mg 20 Softgels for Pain Relief Liquid Filled Capsules for Rapid Release Fever Reducer for Adults Extra Strength](https://m.media-amazon.com/images/I/41vUVanC+UL.jpg)**Belmora Paracetamol Acetaminophen 325mg 20 Softgels for Pain Relief Liquid Filled Capsules for Rapid Release Fever Reducer for Adults Extra Strength**Belmora paracetamol**$8.16**788 rev3y ago](https://www.amazon.com/dp/B0C6B7D1F2) [![Amazon Basic Care Extra Strength Acetaminophen Caplets 500 mg Pain Reliever and Fever Reducer Gentle on Stomach For Arthritis Pain Backache Pain and More 50 Packets of 2 Capsules Each 100 Count](https://m.media-amazon.com/images/I/41fW0WFSB2L.jpg)**Amazon Basic Care Extra Strength Acetaminophen Caplets 500 mg Pain Reliever and Fever Reducer Gentle on Stomach For Arthritis Pain Backache Pain and More 50 Packets of 2 Capsules Each 100 Count**Amazon Basic Care**$8.08**2,310 rev4y ago](https://www.amazon.com/dp/B087D3SML2)

**~~View all new products →~~**

### **Trending**

90-day click momentum

[![GoodMeds Compare to Extra Strength Tylenol | Acetaminophen 500mg Extra Strength Pain Reliever & Fever Reducer | Headache Muscle Aches Back Pain Cold & Flu Relief 500 Count](https://m.media-amazon.com/images/I/41sWH-WMLcL.jpg)**GoodMeds Compare to Extra Strength Tylenol | Acetaminophen 500mg Extra Strength Pain Reliever & Fever Reducer | Headache Muscle Aches Back Pain Cold & Flu Relief 500 Count**GoodMeds**$9.81**4.7★**▲ 232%**](https://www.amazon.com/dp/B0FZNCQYMH) [![Acetaminophen 500mg Extra Strength Rapid Release 400 Gelcaps](https://m.media-amazon.com/images/I/51w6SFptpVL.jpg)**Acetaminophen 500mg Extra Strength Rapid Release 400 Gelcaps**Generic**$30.70**4.8★**▲ 112%**](https://www.amazon.com/dp/B0F6YSGTLL) [![Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever and Fever Reducer for Headache Backache Arthritis Pain Menstrual Cramps 1000 Count (Packaging may vary)](https://m.media-amazon.com/images/I/41aWe6DCfPL.jpg)**Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever and Fever Reducer for Headache Backache Arthritis Pain Menstrual Cramps 1000 Count (Packaging may vary)**Amazon Basic Care**$14.29**4.8★**▲ 107%**](https://www.amazon.com/dp/B083WC1R4Y) [![Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg 200 Count](https://m.media-amazon.com/images/I/41pFWlHrCGL.jpg)**Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg 200 Count**Amazon Basic Care**$5.33**4.8★**▲ 90%**](https://www.amazon.com/dp/B074F2H9VT) [![Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever/Fever Reducer 100 Count](https://m.media-amazon.com/images/I/413HC6tF6nL.jpg)**Amazon Basic Care Extra Strength Pain Relief Acetaminophen Caplets 500 mg Pain Reliever/Fever Reducer 100 Count**Amazon Basic Care**$3.26**4.8★**▲ 58%**](https://www.amazon.com/dp/B096Y26LYD)

**~~View all trending →~~**

## **What buyers say about acetaminophen 500mg**

What buyers praise and complain about, mined from review topics.

### **What buyers love **

**Value For Money**39%

*“they are affordable”*

**Quality-Overall**13%

*“Definitely reliable and affordable—highly recommended”*

**Advertised Vs Actual Product**9%

*“AS ADVERTISED”*

**Efficiency**9%

*“Works Well”*

**Dosage**4%

*“effective as the higher dose pills”*

**Ease Of Use**3%

*“Easy open”*

**Ease Of Chewing/Swallowing**3%

*“Easily swallowed”*

**Ingredients-Overall**2%

*“Great acetaminophen product for great price”*

**Joint Pain**2%

*“My On Going Joint Pain 😩 Works Well For Me”*

**Size-Overall**2%

*“Great size”*

### **What buyers complain about **

**Functionality-Overall**8%

*“the effectiveness just isnt there”*

**Ease Of Chewing/Swallowing**7%

*“Dissolves before swallowing”*

**Size-Overall**7%

*“The bottle is wildly large”*

**Dosage**6%

*“The dosage is not on the bottle”*

**Pain Relief-Overall**6%

*“Doesnt help with pain at all”*

**Value For Money**5%

*“cheaper”*

**Taste-Overall**5%

*“leave a bitter taste”*

**Ease Of Use**4%

*“Cannot use”*

**Quality-Overall**3%

*“No quality control”*

**Strength**2%

*“Not strong at all”*

## **Common questions**

<dl>

<dt>**Is acetaminophen 500mg profitable to sell on Amazon United States?**</dt><dd>The niche generates $260K/yr across 16 tracked products. 1 of 1 products launched in the last 360 days are still selling. 90-day search growth is -8.0%. Flapen's verdict: Skip it (43/100).</dd>

<dt>**How competitive is the acetaminophen 500mg niche?**</dt><dd>8 brands and 75 sellers compete. The top 5 products take 71% of clicks and top 5 brands hold 93% of demand.</dd>

<dt>**What do buyers complain about in acetaminophen 500mg?**</dt><dd>Top complaints mined from reviews: Functionality-Overall, Ease Of Chewing/Swallowing, Size-Overall. The return rate is 0.0%.</dd>

<dt>**When does demand for acetaminophen 500mg peak?**</dt><dd>Demand peaks in Sep–Oct; the busiest month runs 2.6× the quietest.</dd>

<dt>**What does it cost to enter the acetaminophen 500mg niche?**</dt><dd>Listings span $3.26–$30.70; the average listing price is $12.65 (sweet spot $15–$100). The average incumbent carries 35,444 reviews — the moat a new listing must climb.</dd>

</dl>

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