---
title: "Dao Supplement — £197K/yr Amazon UK Niche (2026) - Flapen"
canonical_url: "https://flapen.com/research/uk/health-personal-care/dao-supplement"
last_updated: "2026-07-31T09:45:13.852Z"
locale: en
meta:
  description: "Niche score 53/100 · £197K/yr market · 79K searches/yr. Brand-locked demand (top 5 brands take 96% of clicks) keeps it on the watch list. Data updated Jul 2026."
  "og:description": "Niche score 53/100 · £197K/yr market · 79K searches/yr. Brand-locked demand (top 5 brands take 96% of clicks) keeps it on the watch list. Data updated Jul 2026."
  "og:title": "Dao Supplement — £197K/yr Amazon UK Niche (2026) - Flapen"
---

# **dao supplement**

**Worth a look**

Shows low returns (0.1%), but brand-locked demand (top 5 brands take 96% of clicks) keeps it on the watch list.

Market size 39Growth 24Conversion 86Competition 22Returns 99Price range 95Avg price 95Brand share 10Review moat 74Quality gap 76

**Returns**

**Incredible****0.1%**

return rate — above 5% kills the launch gate

**Avg price**

**Incredible****£25.78**

avg listing price — sweet spot $15–$100

**Price range**

**Incredible****£15.78–£52.02**

cheapest to priciest tracked listing — scored on the share inside $15–$100

**Conversion**

**Great****9.7%**

search→purchase rate — share of searches ending in a sale

**Quality gap**

**Great****4.3★**

avg incumbent rating — lower means beatable quality

**Review moat**

**Good****557.4**

avg incumbent reviews — the moat a new listing must climb

**Market size**

**Okay****£197K**

£197K/yr · 79K searches

**Growth**

**Bad****-2.7%**

90-day search growth — must beat 0% to launch

**Competition**

**Bad****74%**

top-5 click share — a locked-up shelf

**Brand share**

**Bad****96%**

top-5 brand share — brand-locked demand

According to Flapen's Amazon United Kingdom niche tracking, dao supplement is a £197K/yr Amazon United Kingdom market (79K searches/yr). The top 5 brands hold 96% of demand. Verdict: Worth a look — 53/100.

Data updated Jul 25, 2026 · scored weekly · [~~How we score niches ~~](https://flapen.com/research/methodology)

## **dao supplement market data**

<dl>

<dt>**Units sold / yr**</dt><dd>**5K–6K**</dd><dd>avg 250–500/product</dd>

<dt>**Revenue / yr**</dt><dd>**£129K–£155K**</dd><dd>units × avg price</dd>

<dt>**Conversion rate**</dt><dd>**9.7%**</dd>

<dt>**Avg BSR**</dt><dd>**#94**</dd>

<dt>**Page quality**</dt><dd>**0%**</dd>

<dt>**Prime**</dt><dd>**90%**</dd>

<dt>**Sponsored**</dt><dd>**100%**</dd>

<dt>**Out of stock**</dt><dd>**8.2%**</dd>

<dt>**Avg brand age**</dt><dd>**66 months**</dd>

<dt>**Avg seller age**</dt><dd>**162 days**</dd>

</dl>

## **Competition & brand share**

The top 5 products capture 74% of clicks — a locked-up shelf that new listings rarely crack.

**Brands**

**6 **▲rising

**Sellers**

**10**

**Top-5 brand share**

**96%**

Top 20: 100%

**Top-5 click share**

**74%**

Top 20: 100%

**Open market**

**0%**

- NATURDAO37% - DR Healthcare35% - milDAO14% - designs for health5% - Aruanmogu5% - INTOLERAN4%

## **Demand & seasonality**

Weekly Amazon search volume, last 101 weeks — -2.7% search growth over the last 90 days.

2K1KSpike '25 seasonDecMarJunAugNovMarMay

No pronounced peak months · busiest ÷ quietest = 1.4×

[**Open Trend **](https://flapen.com/research/uk/health-personal-care/dao-supplement/trend)

## **Top dao supplement search terms**

- **dao enzyme supplement**31K/yr-4.7%7.2% conv. - **dao**15K/yr+4.1%7.4% conv. - **dao enzyme**9K/yr-6.9%6.0% conv. - **dao supplements histamine**4K/yr+47.7%3.8% conv. - **diamine oxidase**6K/yr-10.7%3.3% conv. - **dao supplement**7K/yr-21.5%5.6% conv. - **dao supplements**5K/yr-12.4%3.7% conv. - **daosin**2K/yr-3.4%3.4% conv. [**All search terms **](https://flapen.com/research/uk/health-personal-care/dao-supplement/search-terms)

## **Top dao supplement products on Amazon**

Each bubble is one product — market share against review moat; bubble size tracks estimated sales, color grades how beatable the incumbent looks.

0%10%£20K20%£39K30%£59K40%£79K1101001K10K Reviews — right = deep review moatMarket share (90d) ≈ est. sales

Beatable (≤4.3★) Contested Strong incumbent (>4.7★)

All 10 tracked products in this niche — three views at once, no toggling.

### **Top sellers**

by 90-day click share

[1![DR Healthcare - DAOfood - DAO Enzyme - Supports the Balance of Dietary Histamine and DAO - Dispenser with 60 Gastro-Resistant DAO Mini-Tablets](https://m.media-amazon.com/images/I/41RAtB4VXeL.jpg)**DR Healthcare - DAOfood - DAO Enzyme - Supports the Balance of Dietary Histamine and DAO - Dispenser with 60 Gastro-Resistant DAO Mini-Tablets**DR Healthcare**£23.34**4.2★954 rev](https://www.amazon.co.uk/dp/B0773V74MV) [2![NATURDAO Plus DAO Enzyme 3 000 000 HDU per Day - Perfect Dosage with 1 000 000 HDU per Tablet (3 Tablets/Day) + 8 Co-Factors & Adjuvants Quercetin Catalase Vitamins Copper & Zinc](https://m.media-amazon.com/images/I/51tcZBVeSiL.jpg)**NATURDAO Plus DAO Enzyme 3 000 000 HDU per Day - Perfect Dosage with 1 000 000 HDU per Tablet (3 Tablets/Day) + 8 Co-Factors & Adjuvants Quercetin Catalase Vitamins Copper & Zinc**NATURDAO**£26.50**4.3★620 rev](https://www.amazon.co.uk/dp/B0CBQ7L6RP) [3![DR Healthcare - DAOfood Plus - DAO Enzyme - Quercetin and Vitamin C - Contributes to the Balance of Dietary Histamine - 60 Capsules with Gastro-Resistant DAO Mini-Tablets](https://m.media-amazon.com/images/I/41v32Tc2VqL.jpg)**DR Healthcare - DAOfood Plus - DAO Enzyme - Quercetin and Vitamin C - Contributes to the Balance of Dietary Histamine - 60 Capsules with Gastro-Resistant DAO Mini-Tablets**DR Healthcare**£24.98**4.2★1,641 rev](https://www.amazon.co.uk/dp/B07T811PFT) [4![NATURDAO DAO Enzyme 3 000 000 HDU per Day - Perfect Dosage with 1 000 000 HDU per Tablet (1 to 3 Tablets/Day) - 100% DAO Vegan - 60 Tablets](https://m.media-amazon.com/images/I/51FC542N7ML.jpg)**NATURDAO DAO Enzyme 3 000 000 HDU per Day - Perfect Dosage with 1 000 000 HDU per Tablet (1 to 3 Tablets/Day) - 100% DAO Vegan - 60 Tablets**NATURDAO**£26.52**4.1★1,877 rev](https://www.amazon.co.uk/dp/B07TV7JS32) [5![milDAO 30 Vegan Tablets | DAO Enzyme Supplement for Histamine Intolerance | Pure & High-Standard Halal-Certified | 1 000 000 HDU per Tablet | with Catalase | Foil Pouch for Maximum Stability](https://m.media-amazon.com/images/I/41-t5AaP6XL.jpg)**milDAO 30 Vegan Tablets | DAO Enzyme Supplement for Histamine Intolerance | Pure & High-Standard Halal-Certified | 1 000 000 HDU per Tablet | with Catalase | Foil Pouch for Maximum Stability**milDAO**£15.78**4.2★141 rev](https://www.amazon.co.uk/dp/B0F5WZMRL7)

**~~View all top sellers →~~**

### **Newest**

by launch date

[![NaturDAO MAX DAO Enzyme Supplement 120 Tablets Adjustable Dosage Extended Release Histamine Blocker](https://m.media-amazon.com/images/I/519uoQ7PuSL.jpg)**NaturDAO MAX DAO Enzyme Supplement 120 Tablets Adjustable Dosage Extended Release Histamine Blocker**NATURDAO**£19.21**22 rev2mo ago](https://www.amazon.co.uk/dp/B0GXWNNHQJ) [![Intoleran DAO Plus Digestive Enzymes - 50 Capsules | Supplement for Histamine Intolerance & DAO Deficiency | Healthy Histamine Levels | 30 000 HDU Diamine Oxidase (DAO) Enzyme | Vitamin C & Quercetin](https://m.media-amazon.com/images/I/31WmqFEseUL.jpg)**Intoleran DAO Plus Digestive Enzymes - 50 Capsules | Supplement for Histamine Intolerance & DAO Deficiency | Healthy Histamine Levels | 30 000 HDU Diamine Oxidase (DAO) Enzyme | Vitamin C & Quercetin**INTOLERAN**£24.29**3 rev4mo ago](https://www.amazon.co.uk/dp/B0FR4WW1HC) [![DAO Supplements Histamine Blocker DAO Enzyme (Diamine Oxidase) & Vitamin C for Gut Health & Food Support 60 Servings](https://m.media-amazon.com/images/I/51gfl5rkS9L.jpg)**DAO Supplements Histamine Blocker DAO Enzyme (Diamine Oxidase) & Vitamin C for Gut Health & Food Support 60 Servings**Aruanmogu**£22.46**18 rev8mo ago](https://www.amazon.co.uk/dp/B0G2CJ7SBS) [![Designs for Health HistaGest-DAO 60 Tablets](https://m.media-amazon.com/images/I/31p5bh5NyNL.jpg)**Designs for Health HistaGest-DAO 60 Tablets**designs for health**£52.02**157 rev1y ago](https://www.amazon.co.uk/dp/B0BSWCCPF5) [![milDAO 30 Vegan Tablets | DAO Enzyme Supplement for Histamine Intolerance | Pure & High-Standard Halal-Certified | 1 000 000 HDU per Tablet | with Catalase | Foil Pouch for Maximum Stability](https://m.media-amazon.com/images/I/41-t5AaP6XL.jpg)**milDAO 30 Vegan Tablets | DAO Enzyme Supplement for Histamine Intolerance | Pure & High-Standard Halal-Certified | 1 000 000 HDU per Tablet | with Catalase | Foil Pouch for Maximum Stability**milDAO**£15.78**141 rev1y ago](https://www.amazon.co.uk/dp/B0F5WZMRL7)

**~~View all new products →~~**

### **Trending**

90-day click momentum

[![NaturDAO MAX DAO Enzyme Supplement 120 Tablets Adjustable Dosage Extended Release Histamine Blocker](https://m.media-amazon.com/images/I/519uoQ7PuSL.jpg)**NaturDAO MAX DAO Enzyme Supplement 120 Tablets Adjustable Dosage Extended Release Histamine Blocker**NATURDAO**£19.21**4.4★**▲ 266%**](https://www.amazon.co.uk/dp/B0GXWNNHQJ) [![milDAO 60 Vegan Tablets | DAO Enzyme Supplement for Histamine Intolerance | Pure & High-Standard Halal-Certified | 1 000 000 HDU per Tablet | with Catalase | Foil Pouch for Maximum Stability](https://m.media-amazon.com/images/I/41ANwsyrruL.jpg)**milDAO 60 Vegan Tablets | DAO Enzyme Supplement for Histamine Intolerance | Pure & High-Standard Halal-Certified | 1 000 000 HDU per Tablet | with Catalase | Foil Pouch for Maximum Stability**milDAO**£22.68**4.2★**▲ 73%**](https://www.amazon.co.uk/dp/B0DPX1TGF7) [![Intoleran DAO Plus Digestive Enzymes - 50 Capsules | Supplement for Histamine Intolerance & DAO Deficiency | Healthy Histamine Levels | 30 000 HDU Diamine Oxidase (DAO) Enzyme | Vitamin C & Quercetin](https://m.media-amazon.com/images/I/31WmqFEseUL.jpg)**Intoleran DAO Plus Digestive Enzymes - 50 Capsules | Supplement for Histamine Intolerance & DAO Deficiency | Healthy Histamine Levels | 30 000 HDU Diamine Oxidase (DAO) Enzyme | Vitamin C & Quercetin**INTOLERAN**£24.29**5.0★**▲ 46%**](https://www.amazon.co.uk/dp/B0FR4WW1HC) [![Designs for Health HistaGest-DAO 60 Tablets](https://m.media-amazon.com/images/I/31p5bh5NyNL.jpg)**Designs for Health HistaGest-DAO 60 Tablets**designs for health**£52.02**4.6★**▲ 27%**](https://www.amazon.co.uk/dp/B0BSWCCPF5) [![milDAO 30 Vegan Tablets | DAO Enzyme Supplement for Histamine Intolerance | Pure & High-Standard Halal-Certified | 1 000 000 HDU per Tablet | with Catalase | Foil Pouch for Maximum Stability](https://m.media-amazon.com/images/I/41-t5AaP6XL.jpg)**milDAO 30 Vegan Tablets | DAO Enzyme Supplement for Histamine Intolerance | Pure & High-Standard Halal-Certified | 1 000 000 HDU per Tablet | with Catalase | Foil Pouch for Maximum Stability**milDAO**£15.78**4.2★**▲ 17%**](https://www.amazon.co.uk/dp/B0F5WZMRL7)

**~~View all trending →~~**

## **What buyers say about dao supplement**

What buyers praise and complain about, mined from review topics.

### **What buyers love **

**Quality-Overall**13%

*“Amazing quality”*

**Regulates Digestion**10%

*“reduces bloating alot for main meals”*

**Value For Money**9%

*“It's very affordable”*

**Side Effects**6%

*“no side effects”*

**Allergies**6%

*“This product along with a low histamine diet would seem to have had a positive impact on my allergy”*

**Efficiency**5%

*“It works”*

**Vegan/Organic**5%

*“Vegan, gluten free and high strength”*

**Fever Relief**4%

*“Superb for histamine reactions”*

**Advertised Vs Actual Product**4%

*“do the job”*

**Dosage**4%

*“so I think this is a good introductory dose”*

### **What buyers complain about **

**Functionality-Overall**19%

*“Not doing the job”*

**Value For Money**13%

*“expensive”*

**Regulates Digestion**7%

*“Digestive enzymes”*

**Magnesium**7%

*“It contains maltodextrin”*

**Dosage**6%

*“Inaccurate Dosing”*

**Allergies**5%

*“So if you think this is for you because you have allergies”*

**Heart Health**3%

*“high heart rate”*

**Durability**3%

*“The dury is still out”*

**Ingredients-Overall**2%

*“The capsules are not huge, and as they also contain vitamin C and rice flour, it's obvious that the amount of Dehydrated Pea Sprout Powder in one capsule is negligible”*

**Vitamin**2%

*“I ordered this supplement knowing what I was getting but on further reflection I think it's not the best option or the best buy if you suffer from histamine intolerance which is a very specific issue and not one that relates to allergies”*

### **Top return reasons **

**Functionality-Overall**29%

**Joint Pain**14%

**Dosage**14%

**Fever Relief**12%

**Acid Regulator/Stomach Ache Relief**12%

**Pain Relief-Overall**7%

**Immunity Booster**7%

**Side Effects**5%

## **Common questions**

<dl>

<dt>**Is dao supplement profitable to sell on Amazon United Kingdom?**</dt><dd>The niche generates £197K/yr across 10 tracked products. 0 of 3 products launched in the last 360 days are still selling. 90-day search growth is -2.7%. Flapen's verdict: Worth a look (53/100).</dd>

<dt>**How competitive is the dao supplement niche?**</dt><dd>6 brands and 10 sellers compete. The top 5 products take 74% of clicks and top 5 brands hold 96% of demand.</dd>

<dt>**What do buyers complain about in dao supplement?**</dt><dd>Top complaints mined from reviews: Functionality-Overall, Value For Money, Regulates Digestion. The return rate is 0.1%.</dd>

<dt>**When does demand for dao supplement peak?**</dt><dd>Demand is steady year-round — the busiest month runs 1.4× the quietest.</dd>

<dt>**What does it cost to enter the dao supplement niche?**</dt><dd>Listings span £15.78–£52.02; the average listing price is £25.78 (sweet spot $15–$100). The average incumbent carries 557 reviews — the moat a new listing must climb.</dd>

</dl>

## **Related niches in Health & Personal Care**

- 69 [**cooling towel**](https://flapen.com/research/uk/health-personal-care/cooling-towel)£1.1M/yr>1,000%**Launch it**- 70 [**collagen**](https://flapen.com/research/uk/health-personal-care/collagen)£6.6M/yr-20.1%**Worth a look**- 70 [**dry skin remover feet**](https://flapen.com/research/uk/health-personal-care/dry-skin-remover-feet)£236K/yr+78.2%**Worth a look**- 70 [**stryde knee strap**](https://flapen.com/research/uk/health-personal-care/stryde-knee-strap)£112K/yr>1,000%**Worth a look**- 70 [**libre 2 sensor covers**](https://flapen.com/research/uk/health-personal-care/libre-2-sensor-covers)£240K/yr+67.1%**Worth a look**- 70 [**water retention tablets**](https://flapen.com/research/uk/health-personal-care/water-retention-tablets)£470K/yr+47.2%**Worth a look**[**All Health & Personal Care niches **](https://flapen.com/research/uk/health-personal-care)